scholarly journals CYP3A4 and CYP3A5 Polymorphisms and Blood Pressure Response to Amlodipine among African-American Men and Women with Early Hypertensive Renal Disease

2010 ◽  
Vol 31 (2) ◽  
pp. 95-103 ◽  
Author(s):  
Vibha Bhatnagar ◽  
Erin P. Garcia ◽  
Daniel T. O’Connor ◽  
Victoria H. Brophy ◽  
John Alcaraz ◽  
...  
2002 ◽  
Vol 11 (4) ◽  
pp. 229-234 ◽  
Author(s):  
Vernon Bond ◽  
Quiona Stephens ◽  
Richard G. Adams ◽  
Paul Vaccaro ◽  
Ronald Demeersman ◽  
...  

2020 ◽  
Vol 30 (2) ◽  
pp. 349-356
Author(s):  
L. Jerome Brandon ◽  
Larry D. Proctor

Objectives: The purpose of this study was to determine if central anthropometric vari­ables that best estimate blood pressure risks in European Americans also best estimate blood pressure risks in African Americans.Design: The participants were 357 nor­motensive African and European American volunteers with a mean age of 32.6 ± 12.4 years. Participants were evaluated for central adiposity with dual energy X-ray ab­sorptiometry, abdomen and thigh skinfolds, waist and hip circumferences, waist/hip ratio, waist/height ratio, body mass index, and systolic and diastolic blood pressures. Descriptive statistics, partial correlations, ANOVA and stepwise regressions were used to analyze the data.Results: Central adiposity anthropometric indices made different contributions to blood pressure in African and European American men and women. When weight was held constant, waist circumference shared stronger partial relationships with blood pressure in African Americans (r = .30 to .47) than in European Americans (r = .11 to .32). Waist circumference in com­bination with other indices was a predictor of systolic and diastolic blood pressures in European American men (P<.05) but only a predictor for diastolic blood pressure in African American men and women (P<.01). Hip circumference was the only predic­tor for systolic blood pressure (P<.01) in African American men and women.Conclusions: Further research on the rela­tive contributions of central anthropometric indices to blood pressure in African and European Americans is warranted. A better understanding of this relationship may help reduce hypertensive morbidity and mortali­ty disparities between African and European Americans. Ethn Dis. 2020;30(2):349-356; doi:10.18865/ed.30.2.349


1988 ◽  
Vol 61 (15) ◽  
pp. 1288-1291 ◽  
Author(s):  
Jacques W.M. Lenders ◽  
Theo De Boo ◽  
Wim A.J. Lemmens ◽  
Joeke Reuenga ◽  
Jacques J. Willemsen ◽  
...  

2000 ◽  
Vol 38 (6) ◽  
pp. 519-526 ◽  
Author(s):  
Domenic A. Sica ◽  
Charles E. Halstenson ◽  
Todd W.B. Gehr ◽  
William F. Keane

2007 ◽  
Vol 100 (12) ◽  
pp. 1795-1801 ◽  
Author(s):  
Sebastian T. Palmeri ◽  
John B. Kostis ◽  
Laurie Casazza ◽  
Lynn A. Sleeper ◽  
Minmin Lu ◽  
...  

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