scholarly journals Familial Creutzfeldt-Jakob Disease with a V180I Mutation: Comparative Analysis with Pathological Findings and Diffusion-Weighted Images

2009 ◽  
Vol 28 (6) ◽  
pp. 550-557 ◽  
Author(s):  
Kazuo Mutsukura ◽  
Katsuya Satoh ◽  
Susumu Shirabe ◽  
Itsuro Tomita ◽  
Takayasu Fukutome ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Pathological Findings ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
Jakob Disease ◽  
And Diffusion

scholarly journals Early Lesion of Creutzfeldt-Jakob Disease Detected by Standardizing Diffusion-Weighted Images

2009 ◽  
Vol 48 (18) ◽  
pp. 1717-1718 ◽  
Author(s):  
Masamitsu Yaguchi ◽  
Hisa Yaguchi ◽  
Tohru Kanaya
Keyword(s):  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
Jakob Disease ◽  
Early Lesion

Total Tau Protein in Cerebrospinal Fluid and Diffusion-Weighted MRI as an Early Diagnostic Marker for Creutzfeldt-Jakob Disease

2007 ◽  
Vol 24 (3) ◽  
pp. 207-212 ◽  
Author(s):  
Katsuya Satoh ◽  
Susumu Shirabe ◽  
Akira Tsujino ◽  
Hiroto Eguchi ◽  
Masakatsu Motomura ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Tau Protein ◽  
Diagnostic Marker ◽  
Diffusion Weighted Mri ◽  
Total Tau ◽  
Diffusion Weighted ◽  
Jakob Disease ◽  
And Diffusion ◽  
Early Diagnostic

scholarly journals Participant Factors That Contribute to Magnetic Resonance Imaging Motion Artifacts in Children With Mild Traumatic Brain Injury or Orthopedic Injury

2021 ◽  
Author(s):  
Ashley L. Ware ◽  
Ayushi Shukla ◽  
Sunny Guo ◽  
Adrian Onicas ◽  
Bryce L. Geeraert ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Motion Artifacts ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Diffusion Weighted Images ◽  
Orthopedic Injury ◽  
Diffusion Weighted ◽  
And Diffusion

Abstract Background: Motion can compromise image quality and confound results, especially in pediatric research. This study evaluated qualitative and quantitative approaches to motion artifacts detection and correction, and whether motion artifacts relate to injury history, age, or sex in children with mild traumatic brain injury or orthopedic injury relative to typically developing children. The concordance between qualitative and quantitative motion ratings was also examined.Method: Children aged 8-16 years with mild traumatic brain injury (n=141) or orthopedic injury (n=73) were recruited from the emergency department and completed an MRI scan roughly 2 weeks post-injury. Typically developing children (n=41) completed a single MRI scan. T1- and diffusion-weighted images were visually inspected and rated for motion artifacts by trained examiners. Quantitative estimates of motion artifacts were derived from FreeSurfer and FSL. Results: Age (younger > older) and sex (boys > girls) were significantly associated with motion artifacts on both T1- and diffusion-weighted images. Children with mild traumatic brain or orthopedic injury had significantly more motion-corrupted diffusion-weighted volumes than typically developing children, but mild traumatic brain injury and orthopedic injury groups did not differ from each other. The exclusion of motion-corrupted volumes did not significantly change diffusion tensor imaging metrics. Discussion: Results indicate that automated quantitative estimates of motion artifacts, which are less labour-intensive than manual methods, are appropriate. Results have implications for the reliability of structural magnetic resonance imaging research and highlight the importance of considering motion artifacts in studies of pediatric mild traumatic brain injury.

scholarly journals Discrepancy between perfusion- and diffusion-weighted images in ischemic stroke

Medicine ◽  
2018 ◽  
Vol 97 (52) ◽  
pp. e13894
Author(s):  
Wook Hur ◽  
Bum Joon Kim ◽  
Byoung-Soo Shin ◽  
Hyun Goo Kang
Keyword(s):  
Ischemic Stroke ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
And Diffusion

scholarly journals Cortical Hyperintensity on Diffusion-weighted Images as the Presymptomatic Marker of Sporadic Creutzfeldt-Jakob Disease

2019 ◽  
Vol 58 (5) ◽  
pp. 727-729 ◽  
Author(s):  
Kengo Maeda ◽  
Yoshiko Sugihara ◽  
Tomoyuki Shiraishi ◽  
Akinori Hirai ◽  
Katsuya Satoh
Keyword(s):  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
Jakob Disease

Correlation of Placental Magnetic Resonance Imaging With Histopathologic Diagnosis: Detection of Aberrations in Structure and Water Diffusivity

2019 ◽  
Vol 23 (4) ◽  
pp. 260-266
Author(s):  
Crystal Bockoven ◽  
Roland D Gastfield ◽  
Thomas Victor ◽  
Palamadai N Venkatasubramanian ◽  
Alice M Wyrwicz ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Relaxation Time ◽  
Magnetic Resonance ◽  
Unknown Etiology ◽  
Placental Pathology ◽  
Resonance Imaging ◽  
Fixed Tissue ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
And Diffusion

Objective Noninvasive methods to identify placental pathologic conditions are being sought in order to recognize these conditions at an earlier stage leading to improved clinical interventions and perinatal outcomes. The objective of this study was to examine fixed tissue slices of placenta by T2- and diffusion-weighted magnetic resonance imaging (MRI) and correlate the images with placental pathologic findings defined by routine gross and histologic examination. Methods Four formalin-fixed placentas with significant placental pathology (maternal vascular malperfusion, chronic villitis of unknown etiology, and massive perivillous fibrin deposition) and 2 histologically normal placentas were evaluated by high-resolution MRI. Representative placental slices were selected (2 cm long and 10 mm wide) and rehydrated. Imaging was performed on a Bruker Avance 14.1 T microimager. Diffusion-weighted images were acquired from 16 slices using slice thickness 0.5 mm and in-plane resolution approximately 100 µm × 100 µm. T2 maps were obtained from the same slices. T2 relaxation time and apparent diffusion coefficient (ADC) were acquired from representative regions of interest and compared between normal and diseased placentas. Results In T2- and diffusion-weighted images, the placental microstructure differed subjectively between diseased and normal placentas. Furthermore, diseased placentas showed statistically significantly longer mean T2 relaxation times and generally higher mean ADC. Conclusion Diffusion- and T2-weighted MRI can potentially be used to detect significant placental pathology by using T2 relaxation time and ADC as markers of altered placental microstructure.

scholarly journals Radiological evaluation of deep soft tissue fibromatosis, the characteristic MR criteria on conventional and corresponding diffusion-weighted images

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Rania Zeitoun ◽  
Sarah Maged Khafagy ◽  
Ikram Hamed Mahmoud ◽  
Nagui Mohamed Abd El-Wahab
Keyword(s):  
Mr Images ◽  
Post Contrast ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
Local Staging ◽  
Diffusion Pattern ◽  
Adc Values ◽  
Characteristic Features ◽  
And Diffusion ◽  
Deep Fibromatosis

Abstract Background To analyze the characteristic features of deep fibromatosis on conventional and diffusion-weighted MR images. Result The lesions were growing along the musculoaponeurotic fascia, mostly invaded the muscles, and showed ill-defined margins, low T2 signal bands and areas, and facial tail sign. Diffusion images showed mostly high or high mixed with low signal; only 2 lesions showed a persistent low signal. The average mean and minimum ADC values were 1.41 ± 0.26 × 10−3 mm2/s and 0.79 ± 0.43 × 10−3 mm2/s respectively. Post-contrast and DWI detected synchronous lesions and extensions missed on T1 and T2 images. Conclusion The most frequent MR features of deep fibromatosis are low T2 signal bands and areas, fascial tail sign, ill or partially defined margins, and predominant restricted diffusion pattern in addition to areas of “T2-blackout effect.” Post-contrast and DWI are more valuable in local staging of the tumor.

scholarly journals Correlation between periodic sharp wave complexes and diffusion-weighted magnetic resonance images in early stage of Creutzfeldt-Jakob disease: A report of two cases

Seizure ◽  
2008 ◽  
Vol 17 (8) ◽  
pp. 717-722 ◽  
Author(s):  
Masahiro Mizobuchi ◽  
Chiharu Tanaka ◽  
Kazuya Sako ◽  
Atsuko Nihira ◽  
Takenori Abe ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Early Stage ◽  
Magnetic Resonance Images ◽  
Sharp Wave ◽  
Diffusion Weighted ◽  
Jakob Disease ◽  
And Diffusion

scholarly journals A groupwise registration and tractography framework for cardiac myofiber architecture description by diffusion MRI: an application to the ventricular junctions

2021 ◽  
Author(s):  
Julie Magat ◽  
Maxime Yon ◽  
Yann Bihan-Poudec ◽  
Valéry Ozenne
Keyword(s):  
High Resolution ◽  
Diffusion Tensor ◽  
Heart Weight ◽  
Probabilistic Algorithms ◽  
Isotropic Resolution ◽  
Anatomical Dissection ◽  
Diffusion Weighted Images ◽  
Diffusion Weighted ◽  
The Individual ◽  
And Diffusion

AbstractBackgroundKnowledge of the normal myocardial–myocyte orientation could theoretically allow the definition of relevant quantitative biomarkers in clinical routine to diagnose heart pathologies. A whole heart diffusion tensor template representative of the global myofiber organization over species is therefore crucial for comparisons across populations. In this study, we developed a template-based and tractography framework to resolve the global myofiber arrangement of large mammalian hearts. To demonstrate the potential application of the proposed method, a novel description of sub-regions in the intraventricular septum is presented.MethodsThree explanted sheep (ovine) hearts (size ~12×8×6 cm3, heart weight ~ 150 g) were perfused with contrast agent and fixative and imaged in a 9.4T magnet. A group-wise registration of high-resolution anatomical and diffusion-weighted images were performed to generated anatomical and diffusion tensor templates. Diffusion tensor metrics (eigenvalues, eigenvectors, fractional anisotropy …) were computed to provide a quantitative and spatially-resolved analysis of cardiac microstructure. Then tractography was performed using deterministic and probabilistic algorithms and used for different purposes: i) Visualization of myofiber architecture, ii) Segmentation of sub-area depicting the same fiber organization, iii) Seeding and Tract Editing. Finally, dissection was performed to confirm the existence of macroscopic structures identified in the diffusion tensor template.ResultsThe template creation takes advantage of high-resolution anatomical and diffusion-weighted images obtained at an isotropic resolution of 150 μm and 600 μm respectively, covering ventricles and atria and providing information on the normal myocardial architecture. The diffusion metric distributions from the template were found close to the one of the individual samples validating the registration procedure. Small new sub-regions exhibiting spatially sharp variations in fiber orientation close to the junctions of the septum and ventricles were identified. Each substructure was defined and represented using streamlines. The existence of a bundle of fibers in the posterior junction was validated by anatomical dissection. A complex structural organization of the anterior junction in comparison to the posterior junction was evidenced by the high-resolution acquisition.ConclusionsA new framework combining cardiac template generation and tractography was applied on the whole sheep heart. The framework can be used for anatomical investigation, characterization of microstructure and visualization of myofiber orientation across samples. Finally, a novel description of the ventricular junction in large mammalian hearts was proposed.

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