Treatment of Darier’s Disease, Lamellar Ichthyosis, Pityriasis Rubra Pilaris, Cystic Acne, and Basal Cell Carcinoma with Oral 13-cis-Retinoic Acid

Dermatology ◽  
1978 ◽  
Vol 157 (1) ◽  
pp. 11-12 ◽  
Author(s):  
G.L. Peck ◽  
F.W. Yoder ◽  
T.G. Olsen ◽  
M.D. Pandya ◽  
D. Butkus
Keyword(s):  
Retinoic Acid ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Lamellar Ichthyosis ◽  
Darier’S Disease ◽  
Pityriasis Rubra Pilaris ◽  
Darier's Disease

scholarly journals Basal Cell Carcinoma in Type 2 Segmental Darier's Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Lynne Robertson ◽  
Maxwell B. Sauder
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Rare Presentation ◽  
Keratosis Follicularis ◽  
Darier’S Disease ◽  
Darier's Disease ◽  
Hands And Feet ◽  
Dominant Condition

Background. Darier's disease (DD), also known as Keratosis Follicularis or Darier-White disease, is a rare disorder of keratinization. DD can present as a generalized autosomal dominant condition as well as a localized or segmental postzygotic condition (Vázquez et al., 2002). Clinical features of DD include greasy, warty papules and plaques on seborrheic areas, dystrophic nails, palmo-plantar pits, and papules on the dorsum of the hands and feet.Objective. We report a case of basal cell carcinoma developing in a patient with type 2 segmental DD.Conclusion. According to the current literature, Type 2 segmental disease is a rare presentation of Darier's disease with only 8 previous cases reported to date. In addition, nonmelanoma skin cancer (NMSC) arising from DD is rarely reported; however, there may be an association between DD and risk of carcinogenesis.

scholarly journals The Effect of 13-cis Retinoic Acid on Epidermal Lysosomal Hydrolase Activity in Darier's Disease and Pityriasis Rubra Pilaris

1980 ◽  
Vol 75 (2) ◽  
pp. 133-135 ◽  
Author(s):  
Roderick M. Farb ◽  
Gerald S. Lazarus ◽  
Alexander Chiaramonti ◽  
Lowell A. Goldsmith ◽  
Robert S. Gilgor ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Hydrolase Activity ◽  
Lysosomal Hydrolase ◽  
Darier’S Disease ◽  
Pityriasis Rubra Pilaris ◽  
Darier's Disease

Basal Cell Carcinoma Masquerading as the Chronic Ectropion of Lamellar Ichthyosis

2008 ◽  
Vol 34 (7) ◽  
pp. 963-967 ◽  
Author(s):  
JEREMY T. KAMPP ◽  
DAVID J. KOUBA ◽  
EDGAR F. FINCHER ◽  
RONALD L. MOY
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Lamellar Ichthyosis

scholarly journals Acitretin systemic and retinoic acid 0.1% cream supression of basal cell carcinoma

2010 ◽  
Vol 2 (1) ◽  
pp. 4 ◽  
Author(s):  
Xi-Bao Zhang ◽  
San-Quan Zhang ◽  
Chang-Xing Li ◽  
Zhen-Ming Huang ◽  
Yu-Wu Luo
Keyword(s):  
Retinoic Acid ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell

Basal Cell Carcinoma Masquerading as the Chronic Ectropion of Lamellar Ichthyosis

2008 ◽  
Vol 34 (7) ◽  
pp. 963-967
Author(s):  
JEREMY T. KAMPP ◽  
DAVID J. KOUBA ◽  
EDGAR F. FINCHER ◽  
RONALD L. MOY
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Lamellar Ichthyosis

scholarly journals Arsenic Trioxide, Itraconazole, All-Trans Retinoic Acid and Nicotinamide: A Proof of Concept for Combined Treatments with Hedgehog Inhibitors in Advanced Basal Cell Carcinoma

Biomedicines ◽  
2020 ◽  
Vol 8 (6) ◽  
pp. 156
Author(s):  
Terenzio Cosio ◽  
Monia Di Prete ◽  
Elena Campione
Keyword(s):  
Retinoic Acid ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Arsenic Trioxide ◽  
Basal Cell ◽  
Hedgehog Pathway ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Advanced Basal Cell Carcinoma

The treatment of advanced basal cell carcinoma has seen a progressive evolution in recent years following the introduction of Hedgehog pathway inhibitors. However, given the burden of mutations in the tumor microenvironment and lack of knowledge for the follow-up of advanced basal cell carcinoma, we are proposing a possible synergistic therapeutic application. Our aim is to underline the use of arsenic trioxide, itraconazole, all-trans-retinoic acid and nicotinamide as possible adjuvant therapies either in advanced not responding basal cell carcinoma or during follow-up based on Hedgehog pathway. We have analyzed the rational use of these drugs as a pivotal point to block neoplasm progression, modulate epigenetic modification and prevent recurrences.

Ultrastructure of Mouse Basal Cell Carcinoma Exhibiting Sebaceous Differentiation

1980 ◽  
Vol 38 ◽  
pp. 738-739
Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Topical Application ◽  
Basal Cell ◽  
Sebaceous Gland ◽  
Rats And Mice ◽  
Mixed Tumors

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.

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