Long-Term Efficacy and Side Effects of Tap Water Iontophoresis of Palmoplantar Hyperhidrosis – the Usefulness of Home Therapy

Dermatology ◽  
1987 ◽  
Vol 175 (3) ◽  
pp. 126-135 ◽  
Author(s):  
E. Hölzle ◽  
N. Alberti
Keyword(s):  
Side Effects ◽  
Tap Water ◽  
Home Therapy ◽  
Term Efficacy

Safety and Long-Term Efficacy of Transition from Sildenafil to Tadalafil due to Side Effects in Patients with Pulmonary Arterial Hypertension

Lung ◽  
2014 ◽  
Vol 193 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Mona Lichtblau ◽  
Dominik Harzheim ◽  
Nicola Ehlken ◽  
Alberto Marra ◽  
Fabiola Pena Pinado ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Side Effects ◽  
Arterial Hypertension ◽  
Term Efficacy ◽  
Pulmonary Arterial

Thirteen-year, long-term efficacy of interferon 2? and interleukin 2-based home therapy in patients with advanced renal cell carcinoma

Cancer ◽  
2002 ◽  
Vol 95 (5) ◽  
pp. 1045-1050 ◽  
Author(s):  
Jens Atzpodien ◽  
Reinhard Hoffmann ◽  
Marcus Franzke ◽  
Christian Stief ◽  
Thomas Wandert ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Interleukin 2 ◽  
Advanced Renal Cell Carcinoma ◽  
Home Therapy ◽  
Term Efficacy

Ruby laser hair removal: Evaluation of long-term efficacy and side effects

2000 ◽  
Vol 26 (2) ◽  
pp. 177-185 ◽  
Author(s):  
Valeria B. Campos ◽  
Christine C. Dierickx ◽  
William A. Farinelli ◽  
Tai-Yuan D. Lin ◽  
Woraphong Manuskiatti ◽  
...  
Keyword(s):  
Side Effects ◽  
Ruby Laser ◽  
Hair Removal ◽  
Laser Hair Removal ◽  
Term Efficacy

Compliance with Tap Water Iontophoresis in Patients with Palmoplantar Hyperhidrosis

2014 ◽  
Vol 18 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Deren Özcan ◽  
A. Tülin Güleç
Keyword(s):  
Side Effects ◽  
Effective Treatment ◽  
Treatment Period ◽  
Initial Treatment ◽  
Maintenance Treatment ◽  
Tap Water ◽  
Medical Data ◽  
Home Therapy ◽  
Effective Treatment Option ◽  
Initial Treatment Period

Background: Patients tend to be noncompliant with tap water iontophoresis (TWI), which is an effective treatment option for palmoplantar hyperhidrosis. Objective: To investigate compliance with TWI in patients with palmoplantar hyperhidrosis and identify the factors limiting its utility. Methods: The medical data of 22 patients treated with TWI for palmoplantar hyperhidrosis were collected. A telephone inquiry questioning overall satisfaction with the treatment and the reasons for discontinuation was conducted. Results: Sixteen patients completed the initial treatment period, and all responded well to the therapy. Eight patients started on the maintenance treatment, five of whom gave up before completing five sessions. The reasons for discontinuation were a lack of time in 12 patients, switching to home therapy in 3 patients, and side effects in 1 patient. Conclusion: Patients with palmoplantar hyperhidrosis are noncompliant with TWI, mainly due to a lack of time. They should be well informed before therapy and be encouraged to have a home device for maintenance.

scholarly journals A retrospective study on long-term efficacy of intranasal lysine-aspirin in controlling NSAID-exacerbated respiratory disease

2021 ◽  
Author(s):  
Alfonso Luca Pendolino ◽  
Glenis K. Scadding ◽  
Bruno Scarpa ◽  
Peter J. Andrews
Keyword(s):  
Side Effects ◽  
Respiratory Disease ◽  
Sinus Surgery ◽  
Lower Airway ◽  
Nasal Airflow ◽  
Term Efficacy ◽  
Clinical Biomarkers ◽  
Revision Sinus Surgery

Abstract Purpose Aspirin treatment after desensitization (ATAD) represents an effective therapeutic option suitable for NSAID-exacerbated respiratory disease (N-ERD) patients with recalcitrant disease. Intranasal administration of lysine-aspirin (LAS) has been suggested as a safer and faster route than oral ATAD but evidence for its use is less strong. We investigated nasal LAS therapy long-term efficacy based on objective outcomes, smell function, polyp recurrence and need for surgery or rescue therapy. Clinical biomarkers predicting response to intranasal LAS, long-term side effects and consequences of discontinuing treatment have been evaluated. Methods A retrospective analysis of a database of 60 N-ERD patients seen between 2012 and 2020 was performed in March 2021. They were followed up at 3-months, 1-, 2- and 3-years with upper and lower airway functions assessed at each follow-up. Results Higher nasal airflow and smell scores were found at each follow-up in patients taking LAS (p < 0.001 and p = 0.048 respectively). No influence of LAS on pulmonary function measurements was observed. Patient on intranasal LAS showed a lower rate of revision sinus surgery when compared to those who discontinued the treatment (p < 0.001). None of the variables studied was found to influence LAS treatment response. Conclusion Our study demonstrates the clinical effectiveness of long-term intranasal LAS in the management of N-ERD in terms of improved nasal airflow and olfaction and a reduced need for revision sinus surgery. Intranasal LAS is safe, being associated with a lower rate of side effects when compared to oral ATAD. However, discontinuation of the treatment at any stage is associated with a loss of clinical benefit.

PO-1485 Radiotherapy for Ledderhose disease: long-term efficacy, side effects and patient-rated outcome

2021 ◽  
Vol 161 ◽  
pp. S1216
Author(s):  
A. de Haan ◽  
J. van Nes ◽  
P. Werker ◽  
J. Langendijk ◽  
R. Steenbakkers
Keyword(s):  
Side Effects ◽  
Term Efficacy ◽  
Ledderhose Disease

Long-term efficacy and side effects of low-dose tacrolimus for the treatment of Myasthenia Gravis

2016 ◽  
Vol 38 (2) ◽  
pp. 325-330 ◽  
Author(s):  
Xiaoyong Tao ◽  
Wei Wang ◽  
Feng Jing ◽  
Zhongkui Wang ◽  
Yuping Chen ◽  
...  
Keyword(s):  
Side Effects ◽  
Myasthenia Gravis ◽  
Low Dose ◽  
Term Efficacy

scholarly journals Bilateral adrenalectomy in the 21st century: when to use it for hypercortisolism?

2016 ◽  
Vol 23 (2) ◽  
pp. R131-R142 ◽  
Author(s):  
Carole Guerin ◽  
David Taieb ◽  
Giorgio Treglia ◽  
Thierry Brue ◽  
André Lacroix ◽  
...  
Keyword(s):  
Side Effects ◽  
21St Century ◽  
Bilateral Adrenalectomy ◽  
Therapeutic Options ◽  
Adrenal Hyperplasia ◽  
Term Efficacy ◽  
Efficient Management ◽  
Low Toxicity ◽  
Fast Acting

Therapeutic options available for the treatment of Cushing's syndrome (CS) have expanded over the last 5 years. For instance, the efficient management of severe hypercortisolism using a combination of fast-acting steroidogenesis inhibitors has been reported. Recent publications on the long-term efficacy of drugs or radiation techniques have also demonstrated low toxicity. These data should encourage endocrinologists to reconsider the place of bilateral adrenalectomy in patients with ACTH-dependent aetiologies of CS; similarly, the indication of bilateral adrenalectomy is reassessed in primary bilateral macronodular adrenal hyperplasia. The objective of this review is to compare the efficacy and side effects of the various therapeutic options of hypercortisolism with those of bilateral adrenalectomy, in order to better define its indications in the 21st century.

scholarly journals Long-Term Efficacy and Safety of Intravenous Injection of Clonal Mesenchymal Stem Cells Derived From Bone Marrow in Five Adults With Moderate to Severe Atopic Dermatitis

2020 ◽  
Author(s):  
Hyun-Tae Shin ◽  
Si Hyub Lee ◽  
Hee Seong Yoon ◽  
Ji Hye Heo ◽  
Seon Bok Lee ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Side Effects ◽  
Clinical Response ◽  
Response Assessment ◽  
Severity Index ◽  
Severe Atopic Dermatitis ◽  
Efficacy And Safety ◽  
Mesenchymal Stem Cell Therapy ◽  
Term Efficacy

Abstract Atopic dermatitis is a chronic and relapsing inflammatory skin disease that is treated with immunosuppressants. However, long-term use of immunosuppressants may cause toxicity and severe side effects. To confirm the long-term efficacy and safety of clonal mesenchymal stem cell therapy, we performed investigator-initiated clinical trials and long-term observation in five adult patients with moderate to severe atopic dermatitis that was refractory to conventional treatments. The clinical response assessment values such as eczema area and severity index (EASI) improved significantly at 16 weeks, and 80% (4/5) of the patients achieved EASI-50 after one or two treatment cycles. Patients were observed for long-term efficacy and safety for an average of 38 weeks (range: 16–86 weeks) and showed no serious side effects. Among the cytokines tested, CCL-17, IL-13 and IL-22 significantly decreased at the endpoint of the five participants, two patients who maintained good clinical response over 84 weeks showed increased IL-17 cytokine levels in the blood.

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