Effects of Birth Asphyxia on Urinary Organic Acid Excretion

Neonatology ◽  
1992 ◽  
Vol 61 (3) ◽  
pp. 162-172 ◽  
Author(s):  
V. Walker ◽  
G.A. Mills
Keyword(s):  
Organic Acid ◽  
Birth Asphyxia ◽  
Acid Excretion ◽  
Urinary Organic Acid

Carnitine Metabolism and Urinary Organic Acid Excretion in Reye's Syndrome and Salicylate Intoxication.

1990 ◽  
Vol 32 (4) ◽  
pp. 406-409 ◽  
Author(s):  
Masaki Takayanagi ◽  
Hiroaki Kakinuma ◽  
Shigenori Yamamoto ◽  
Hironori Nakajima
Keyword(s):  
Organic Acid ◽  
Acid Excretion ◽  
Urinary Organic Acid ◽  
Reye's Syndrome ◽  
Carnitine Metabolism ◽  
Salicylate Intoxication

Urinary organic acid excretion by babies born before 33 weeks of gestation.

1989 ◽  
Vol 35 (7) ◽  
pp. 1460-1466 ◽  
Author(s):  
V Walker ◽  
G A Mills
Keyword(s):  
Organic Acid ◽  
Clinical Care ◽  
Fused Silica ◽  
Gas Liquid Chromatography ◽  
Acid Excretion ◽  
Urinary Organic Acid ◽  
Fused Silica Capillary ◽  
First Time ◽  
Silica Capillary Column ◽  
Normal Neonates

Abstract Using analytical procedures that are widely used by laboratories investigating metabolic disorders, we investigated urinary organic acid excretion by premature neonates who were receiving the usual clinical care. Our purpose was to provide a basis for the diagnosis of inherited organic acid defects. We analyzed 127 random (untimed) urine samples collected weekly from 22 infants of 25-32 weeks of gestation (median, 28 weeks). A wide variety of organic acids was excreted. After oximation, they were extracted with ethyl acetate and diethyl ether, derivatized to trimethylsilyl forms, and analyzed by gas-liquid chromatography on a nonpolar fused silica capillary column, with mass spectrometry for identification. Profiles for individual babies varied markedly on different occasions, reflecting their metabolic status and bacterial activity in the gut. There was no significant ketonuria. Three metabolites identified for the first time in urine from normal neonates were 2,3-butanediol, 3-hydroxy-2-butanone (acetoin), and 4-hydroxy-3-methoxyphenyllactic acid. Significantly increased excretion of 4-hydroxyphenyllactic acid and other phenolic acids occurred during parenteral feeding.

A rare progressive neurometabolic disease (L-2-hydroxyglutaric aciduria) diagnosed by urinary organic acid analysis

2006 ◽  
Vol 37 (03) ◽  
Author(s):  
S Vlaho ◽  
S Posselt ◽  
V Boda ◽  
M Baz Bartels ◽  
S Parbel ◽  
...  
Keyword(s):  
Organic Acid ◽  
Urinary Organic Acid ◽  
Organic Acid Analysis ◽  
Urinary Organic Acid Analysis

scholarly journals Organic Acid Excretion in Penicillium ochrochloron Increases with Ambient pH

2012 ◽  
Vol 3 ◽  
Author(s):  
Pamela Vrabl ◽  
Viktoria Fuchs ◽  
Barbara Pichler ◽  
Christoph W. Schinagl ◽  
Wolfgang Burgstaller
Keyword(s):  
Organic Acid ◽  
Acid Excretion

Organic acid excretion in a patient with 3-hydroxy-3-methylglutaryl-Coa lyase deficiency: Facts and artefacts

1978 ◽  
Vol 90 (2) ◽  
pp. 187-193 ◽  
Author(s):  
M. Duran ◽  
D. Retting ◽  
S.K. Wadman ◽  
C. Jakobs ◽  
R.B.H. Schutgens ◽  
...  
Keyword(s):  
Organic Acid ◽  
Acid Excretion ◽  
Lyase Deficiency
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