Age-Related Changes in the Kinetics of Iron Absorption across the Guinea Pig Proximal Intestine in vivo

Neonatology ◽  
1988 ◽  
Vol 53 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Surjit K.S. Srai ◽  
Edward S. Debnam ◽  
Margot Boss ◽  
Owen Epstein
Keyword(s):  
Guinea Pig ◽  
Iron Absorption ◽  
Age Related ◽  
Proximal Intestine ◽  
Kinetics Of ◽  
Age Related Changes

Age-related changes in the levels and kinetics of pulmonary cytokine and chemokine responses to Streptococcuspneumoniae in mouse pneumonia models

Cytokine ◽  
2018 ◽  
Vol 111 ◽  
pp. 389-397 ◽  
Author(s):  
Philipp Janesch ◽  
Lukas Stulik ◽  
Harald Rouha ◽  
Cecilia Varga ◽  
Jacqueline Steinhäuser ◽  
...  
Keyword(s):  
Age Related ◽  
Kinetics Of ◽  
Age Related Changes

Age-related changes in motility and in nitregic myenteric neurons in guinea pig distal colon

2003 ◽  
Vol 124 (4) ◽  
pp. A545 ◽  
Author(s):  
Paul R. Wade ◽  
Brian Gulbransen ◽  
Jacob Lieb
Keyword(s):  
Guinea Pig ◽  
Distal Colon ◽  
Myenteric Neurons ◽  
Age Related ◽  
Age Related Changes

scholarly journals Age-related changes in collagen synthesis and degradation in rat tissues. Importance of degradation of newly synthesized collagen in regulating collagen production

1991 ◽  
Vol 276 (2) ◽  
pp. 307-313 ◽  
Author(s):  
P K Mays ◽  
R J McAnulty ◽  
J S Campa ◽  
G J Laurent
Keyword(s):  
Skeletal Muscle ◽  
Collagen Synthesis ◽  
Rat Tissues ◽  
Age Related ◽  
Developmental Growth ◽  
Cross Links ◽  
Fractional Synthesis ◽  
Synthesis And Degradation ◽  
Age Related Changes

During developmental growth, collagens are believed to be continuously deposited into an extracellular matrix which is increasingly stabilized by the formation of covalent cross-links throughout life. However, the age-related changes in rates of synthetic and degradative processes are less well understood. In the present study we measured rates of collagen synthesis in vivo using a flooding dose of unlabelled proline given with [14C]proline and determining production of hydroxy[14C]proline. Degradation of newly synthesized collagen was estimated from the amount of free hydroxy [14C]proline in tissues 30 min after injection. Collagen fractional synthesis rates ranged from about 5%/day in skeletal muscle to 20%/day in hearts of rats aged 1 month. At 15 months of age, collagen fractional synthesis rates had decreased markedly in lung and skin, but in skeletal muscle and heart, rates were unchanged. At 24 months of age, synthesis rates had decreased by at least 10-fold in all tissues, compared with rates at 1 month. The proportion of newly synthesized collagen degraded ranged from 6.4 +/- 0.4% in skin to 61.6 +/- 5.0% in heart at 1 month of age. During aging the proportion degraded increased in all tissues to maximal values at 15 months, ranging from 56 +/- 7% in skin to 96 +/- 1% in heart. These data suggest that there are marked age-related changes in rates of collagen metabolism. They also indicate that synthesis is active even in old animals, where the bulk of collagens produced are destined to be degraded.

In vivo quantification of age-related changes in human cortical bone thickness and porosity by HR-pQCT

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S22
Author(s):  
K.K. Nishiyama ◽  
H.M. Macdonald ◽  
H.R. Buie ◽  
D.A. Hanley ◽  
S.K. Boyd
Keyword(s):  
Cortical Bone ◽  
Bone Thickness ◽  
Cortical Bone Thickness ◽  
Human Cortical Bone ◽  
Age Related ◽  
Age Related Changes

scholarly journals Age-related changes in the secretion of LH in vivo and in vitro in infantile and prepubertal Holstein bull calves

Reproduction ◽  
1994 ◽  
Vol 101 (2) ◽  
pp. 453-458 ◽  
Author(s):  
J. M. McAndrews ◽  
J. L. Peters ◽  
D. R. Deaver
Keyword(s):  
Holstein Bull ◽  
Age Related ◽  
Bull Calves ◽  
Age Related Changes
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