The Effect of Early Menarche on Later Body Composition and Fat Distribution in Female Adolescents: Role of Birth Weight

2009 ◽  
Vol 54 (4) ◽  
pp. 313-320 ◽  
Author(s):  
Idoia Labayen ◽  
Francisco B. Ortega ◽  
Luis A. Moreno ◽  
Carlos Redondo-Figuero ◽  
Gloria Bueno ◽  
...  
2003 ◽  
Vol 11 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Saskia J. te Velde ◽  
Jos W.R. Twisk ◽  
Willem van Mechelen ◽  
Han C.G. Kemper

Obesity ◽  
2008 ◽  
Vol 16 (7) ◽  
pp. 1680-1686 ◽  
Author(s):  
Idoia Labayen ◽  
Luis A. Moreno ◽  
Jonatan R. Ruiz ◽  
Marcela González-Gross ◽  
Julia Wärnberg ◽  
...  

2011 ◽  
pp. 253-261 ◽  
Author(s):  
M. DUŠKOVÁ ◽  
H. POSPÍŠILOVÁ

Dihydrotestosterone (DHT) originates via irreversible reduction of testosterone by catalytic activity of 5α-reductase enzyme and it is demonstratively the most effective androgen. Androgens influence adipose tissue in men either directly by stimulation of the androgen receptor or indirectly, after aromatization, by acting at the estrogen receptor. DHT as a non-aromatizable androgen could be responsible for a male type fat distribution. The theory of non-aromatizable androgens as a potential cause of a male type obesity development has been studied intensively. However, physiological levels of DHT inhibit growth of mature adipocytes. In animal models, substitution of DHT in males after gonadectomy has a positive effect on body composition as a testosterone therapy. Thus, DHT within physiological range positively influences body composition. However, there are pathological conditions with an abundance of DHT, e.g. androgenic alopecia and benign prostatic hyperplasia. These diseases are considered as risk factors for development of metabolic syndrome or atherosclerosis. In obese people, DHT metabolism in adipose tissue is altered. Local abundance of non-aromatizable androgen has a negative effect on adipose tissue and it could be involved in pathogenesis of metabolic and cardiovascular diseases. Increased DHT levels, compared to physiological levels, have negative effect on development of cardiovascular diseases. Difference between the effect of physiological and increased level brings about certain paradox.


2012 ◽  
Vol 97 (Suppl 2) ◽  
pp. A410-A410
Author(s):  
M. D. Beer ◽  
M. V. Eijsden ◽  
T. Vrijkotte ◽  
C. Fall ◽  
C. Osmond ◽  
...  

1997 ◽  
Vol 241 (3) ◽  
pp. 195-203 ◽  
Author(s):  
R. PASQUALI ◽  
F. CASIMIRRI ◽  
G. PASCAL ◽  
O. TORTELLI ◽  
A. M. MORSELLI LABATE ◽  
...  

2020 ◽  
Vol 16 (2) ◽  
pp. 142-154 ◽  
Author(s):  
Hadi Emamat ◽  
Zahra Yari ◽  
Hossein Farhadnejad ◽  
Parvin Mirmiran

Recent evidence has highlighted that fat accumulation, particularly abdominal fat distribution, is strongly associated with metabolic disturbance. It is also well-recognized that the metabolic responses to variations in macronutrients intake can affect body composition. Previous studies suggest that the quality of dietary fats can be considered as the main determinant of body-fat deposition, fat distribution, and body composition without altering the total body weight; however, the effects of dietary fats on body composition have controversial results. There is substantial evidence to suggest that saturated fatty acids are more obesogen than unsaturated fatty acids, and with the exception of some isomers like conjugate linoleic acid, most dietary trans fatty acids are adiposity enhancers, but there is no consensus on it yet. On the other hand, there is little evidence to indicate that higher intake of the n-3 and the n-6 polyunsaturated fatty acids can be beneficial in attenuating adiposity, and the effect of monounsaturated fatty acids on body composition is contradictory. Accordingly, the content of this review summarizes the current body of knowledge on the potential effects of the different types of dietary fatty acids on body composition and adiposity. It also refers to the putative mechanisms underlying this association and reflects on the controversy of this topic.


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