Pancreatic Glucagon Does not Alter Mucosal Growth and Maturation of Sucrase and Thymidine Kinase Activity in Rat Small Intestine

Neonatology ◽  
1983 ◽  
Vol 43 (5-6) ◽  
pp. 253-262 ◽  
Author(s):  
Jean-Paul Buts ◽  
Roger de Meyer ◽  
Marie-Paule van Craynest ◽  
Paul Maldague
Keyword(s):  
Small Intestine ◽  
Thymidine Kinase ◽  
Kinase Activity ◽  
Rat Small Intestine ◽  
Thymidine Kinase Activity ◽  
Pancreatic Glucagon ◽  
Mucosal Growth

A growth-stimulating activity derived from the proximal small intestine is associated with an adaptive response

1990 ◽  
Vol 68 (5) ◽  
pp. 646-649 ◽  
Author(s):  
V. L. Grey ◽  
C. L. Morin
Keyword(s):  
Cell Proliferation ◽  
Small Intestine ◽  
Thymidine Kinase ◽  
Kinase Activity ◽  
Crypt Cell ◽  
General Mechanism ◽  
Cell Renewal ◽  
Thymidine Kinase Activity ◽  
Crypt Cell Proliferation ◽  
Proximal Intestine

Luminal nutrition is important for the maintenance of small intestinal structure and function. The equilibrium between crypt cell production and villous cell loss in the mucosal epithelium of the small intestine is altered under certain conditions such as after a small bowel resection. Immediately after resection, there is a marked increase in crypt cell proliferation giving rise to an adaptive hyperplasia in the remnant intestine and for this response luminal nutrition is a critical factor. We have previously demonstrated the presence of a growth-stimulating (GS) activity in a heat-stable acidic extract of the rat proximal intestine 24, 48, and 96 h after resection, which is coincidental with an increase in crypt cell proliferation as measured by thymidine kinase activity. Eight days after resection when the GS activity is no longer detectable, the thymidine kinase activity returns to control values. The molecular weights of the peptides associated with this GS activity are 4500 and 1500, as determined by Sephadex gel filtration. Of note is that the oral intake of food is necessary for the appearance of the GS activity postoperatively. The presence of the GS activity has also been demonstrated upon refeeding after a fast, as well as at weaning in the rat, two physiological situations known to be associated with increased proliferation in the small intestine. This GS activity in the proximal intestine first detected in the resection model may represent a general mechanism by which food controls the cell renewal pattern of the small intestine.Key words: stimulating activity, proximal intestine, adaptation.

Thymidine Kinase Activity Is Reduced in the Developing Staggerer Cerebellum

1981 ◽  
Vol 37 (6) ◽  
pp. 1610-1612 ◽  
Author(s):  
Anne Messer ◽  
Michael Savage ◽  
Thomas P. Carter
Keyword(s):  
Thymidine Kinase ◽  
Kinase Activity ◽  
Thymidine Kinase Activity

scholarly journals Increased Serum Thymidine Kinase Activity in Acute Sarcoidosis.

2002 ◽  
Vol 41 (2) ◽  
pp. 129-132 ◽  
Author(s):  
Syunji TAJIMA ◽  
Yoshichika SANDO ◽  
Toshitaka MAENO ◽  
Naoki SAGAWA ◽  
Mami NARA ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Kinase Activity ◽  
Thymidine Kinase Activity

Elevated serum thymidine kinase activity in canine splenic hemangiosarcoma*

2011 ◽  
Vol 10 (4) ◽  
pp. 292-302 ◽  
Author(s):  
D. H. Thamm ◽  
D. A. Kamstock ◽  
C. R. Sharp ◽  
S. I. Johnson ◽  
E. Mazzaferro ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Kinase Activity ◽  
Elevated Serum ◽  
Thymidine Kinase Activity

Effects of estrogen and progesterone on thymidine kinase activity in the immature rat uterus

1983 ◽  
Vol 145 (6) ◽  
pp. 711-715 ◽  
Author(s):  
Shinobu Sakamoto ◽  
Akio Abe ◽  
Hideki Kudo ◽  
Noriko Yamada ◽  
Keiko Seki ◽  
...  
Keyword(s):  
Thymidine Kinase ◽  
Kinase Activity ◽  
Thymidine Kinase Activity ◽  
Rat Uterus ◽  
Immature Rat

Effects of carcinogenesis on colonic thymidine kinase activity in familial adenomatous polyposis

1992 ◽  
Vol 13 (5) ◽  
pp. 873-876 ◽  
Author(s):  
Shinobu Sakamoto ◽  
Noriyuki Kasahara ◽  
Hideki Kudo ◽  
Takeo Iwama
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Thymidine Kinase ◽  
Kinase Activity ◽  
Adenomatous Polyposis ◽  
Thymidine Kinase Activity
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