Effect of Cyclic Nucleotides on Weight of Gastrocnemius and Creatine Kinase Activity after Denervation of Muscle in Young Rats

Neonatology ◽  
1979 ◽  
Vol 36 (3-4) ◽  
pp. 160-167 ◽  
Author(s):  
H.J. Kloosterboer ◽  
H. van Faassen ◽  
S.A. Stoker-de Vries ◽  
F.A. Hommes
Keyword(s):  
Creatine Kinase ◽  
Cyclic Nucleotides ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Young Rats

Single dose and repeated administrations of liraglutide alter energy metabolism in the brains of young and adult rats

2016 ◽  
Vol 94 (5) ◽  
pp. 451-458 ◽  
Author(s):  
Morgana Prá ◽  
Gabriela Kozuchovski Ferreira ◽  
Aline Haas de Mello ◽  
Rosiane de Bona Schraiber ◽  
Larissa Colonetti Cardoso ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Single Dose ◽  
Energy Metabolism ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Daily Injection ◽  
Adult Rats ◽  
Posterior Cortex ◽  
Young Rats ◽  
Repeated Administrations

Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue that was recently approved to treat obesity in some countries. Considering that liraglutide effects on brain energy metabolism are little known, we evaluated the effects of liraglutide on the energy metabolism. Animals received a single or daily injection of saline or liraglutide during 7 days (25, 50, 100, or 300 μg/kg i.p.). Twenty-four hours after the single or last injection, the rats were euthanized and the hypothalamus, prefrontal cortex, cerebellum, hippocampus, striatum, and posterior cortex were isolated. Our results demonstrated that a single dose of liraglutide in young rats increased the activity of complexes and inhibited creatine kinase activity. Repeated administrations of liraglutide in young rats reduced the activity of complexes and activated creatine kinase activity. In adult rats, a single dose of liraglutide reduced the activity of complex I and creatine kinase and increased the activity of complexes II and IV. Repeated administrations of liraglutide in adult rats increased the activity of complexes I and IV and reduced the activity of complex II and creatine kinase. We concluded that liraglutide may interfere in energy metabolism, because analysis of different times of administrations, concentrations, and level of brain development leads to divergent results.

D-2-Hydroxyglutaric acid inhibits creatine kinase activity from cardiac and skeletal muscle of young rats

2003 ◽  
Vol 33 (10) ◽  
pp. 840-847 ◽  
Author(s):  
C. G. Da Silva ◽  
A. R. F. Bueno ◽  
P. F. Schuck ◽  
G. Leipnitz ◽  
C. A. J. Ribeiro ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Creatine Kinase ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Young Rats ◽  
Hydroxyglutaric Acid

scholarly journals Inhibition of Creatine Kinase Activity by Cystine in the Kidney of Young Rats

2006 ◽  
Vol 60 (2) ◽  
pp. 190-195 ◽  
Author(s):  
Virginia Cielo Rech ◽  
Genaro Azambuja Athaydes ◽  
Luciane Rosa Feksa ◽  
Paula Karine Barcelos Dornelles ◽  
Valnes Rodrigues-Junior ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Young Rats

Tyrosine inhibits creatine kinase activity in cerebral cortex of young rats

2011 ◽  
Vol 26 (3) ◽  
pp. 221-227 ◽  
Author(s):  
Rodrigo Binkowski de Andrade ◽  
Tanise Gemelli ◽  
Denise Bertin Rojas ◽  
Cláudia Funchal ◽  
Carlos Severo Dutra-Filho ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Cerebral Cortex ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Young Rats

Inhibition of creatine kinase activity by 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one in the cerebral cortex and cerebellum of young rats

2010 ◽  
Vol 30 (6) ◽  
pp. 611-616 ◽  
Author(s):  
Rodrigo Binkowski de Andrade ◽  
Tanise Gemelli ◽  
Robson Brum Guerra ◽  
Cláudia Funchal ◽  
Clovis Milton Duval Wannmacher
Keyword(s):  
Creatine Kinase ◽  
Cerebral Cortex ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Young Rats

Distribution of serum creatine kinase activity in young healthy persons

1999 ◽  
Vol 279 (1-2) ◽  
pp. 107-115 ◽  
Author(s):  
Eli I. Lev ◽  
Ilan Tur-Kaspa ◽  
Isaac Ashkenazy ◽  
Anat Reiner ◽  
David Faraggi ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Healthy Persons
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