Effect of Hypoxia on Monoamine Synthesis in Brains of Developing Rats

Neonatology ◽  
1977 ◽  
Vol 31 (1-2) ◽  
pp. 122-126 ◽  
Author(s):  
T. Hedner ◽  
P. Lundborg ◽  
J. Engel
Keyword(s):  
1993 ◽  
Vol 72 (6) ◽  
pp. 398-406 ◽  
Author(s):  
Sven Ahlenius ◽  
Viveka Hillegaart ◽  
Peter Salmi ◽  
Agneta Wijkström

2012 ◽  
Vol 6 (4) ◽  
pp. 272-277 ◽  
Author(s):  
V. B. Narkevich ◽  
I. P. Ovchinnikova ◽  
P. M. Klodt ◽  
V. S. Kudrin

Abstracts ◽  
1977 ◽  
pp. 546
Author(s):  
Wolfgang Kehr ◽  
Wolfgang Speckenbach ◽  
Renate Zimmermann
Keyword(s):  

1985 ◽  
Vol 44 (3) ◽  
pp. 852-855 ◽  
Author(s):  
Christopher J. Schmidt ◽  
Patricia K. Somalia ◽  
Glen R. Hanson ◽  
Michael A. Peat ◽  
James W. Gibb

Author(s):  
Phillip L. Pearl ◽  
William P. Welch

The pediatric neurotransmitter disorders represent an enlarging group of neurological syndromes characterized by inherited abnormalities of neurotransmitter synthesis, metabolism, and transport. Disorders involving monoamine synthesis include guanosine triphosphate cyclohydrolase deficiency (Segawa disease or classical Dopa-responsive dystonia as the heterozygous form), aromatic amino acid decarboxylase deficiency, tyrosine hydrolase deficiency, sepiapterin reductase deficiency, and disorders of tetrahydrobiopterin synthesis. These disorders can be classified according to whether they feature elevated serum levels of phenylalanine. Disorders of γ-amino butyric acid (GABA) metabolism include succinic semialdehyde dehydrogenase deficiency and GABA-transaminase deficiency. Glycine encephalopathy is typically manifested by refractory neonatal seizures due to a defect in the glycine degradative pathway. Pyridoxine-responsive seizures have now been associated with deficiency of α-aminoadipic semialdehyde dehydrogenase as well as a variants requiring therapy with pyridoxal-5-phosphate and folinic acid.


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