scholarly journals Allergen Avoidance Approaches in Food Allergy Management

Author(s):  
Sibylle Koletzko ◽  
Berthold Koletzko
Life ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1275
Author(s):  
Adli Ali ◽  
Nur Hana Hamzaid ◽  
Noor Akmal Shareela Ismail

Food allergy in children has been a common issue due to the challenges of prescribing personalized nutrition with a lack of nutriepigenomics data. This has indeed further influenced clinical practice for appropriate management. While allergen avoidance is still the main principle in food allergy management, we require more information to advance the science behind nutrition, genes, and the immune system. Many researchers have highlighted the importance of personalized nutrition but there is a lack of data on how the decision is made. Thus, this review highlights the relationship among these key players in identifying the solution to the clinical management of food allergy with current nutriepigenomics data. The discussion integrates various inputs, including clinical assessments, biomarkers, and epigenetic information pertaining to food allergy, to curate a holistic and personalized approach to food allergy management in particular.


2020 ◽  
Vol 90 (5) ◽  
pp. 395-406
Author(s):  
Roxanne Dupuis ◽  
Eliza Whiteman Kinsey ◽  
Jonathan M. Spergel ◽  
Terri Brown‐Whitehorn ◽  
Amy Graves ◽  
...  

2017 ◽  
Vol 15 (3) ◽  
pp. 20-24
Author(s):  
Tabatha R. Mauldin

2020 ◽  
Vol 8 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Aikaterini Anagnostou ◽  
Jonathan O’B. Hourihane ◽  
Matthew Greenhawt

2020 ◽  
Vol 8 (9) ◽  
pp. 2851-2857 ◽  
Author(s):  
Douglas P. Mack ◽  
Edmond S. Chan ◽  
Marcus Shaker ◽  
Elissa M. Abrams ◽  
Julie Wang ◽  
...  

2018 ◽  
Vol 72 (Suppl. 3) ◽  
pp. 33-45 ◽  
Author(s):  
Ralf G. Heine

In view of the dramatic rise in the prevalence of food allergy globally, effective prevention strategies have become a public health priority. Several models have emerged around the etiology of food allergy, including the hygiene hypothesis, dual allergen exposure hypothesis, and vitamin D hypothesis. These form the basis for current and potential prevention strategies. Breastfeeding remains a key pillar of primary allergy prevention. Other nutritional interventions, including the use of whey-based, partially hydrolyzed formula in non-breastfed infants, also play an important role. In recent years, there has been a shift away from prolonged food allergen avoidance to the proactive allergen introduction from 4 months of age. This approach is supported by 2 pivotal randomized clinical trials showing that the early introduction of peanut and other food allergens significantly reduces the risk of food allergy. However, the implementation of this strategy at the population level still raises significant logistic problems, including patient selection and development of suitable food formats for young infants. Other prevention strategies, including vitamin D supplementation, are currently under evaluation. Maternal elimination diets during pregnancy and lactation are not recommended for allergy prevention. The treatment of food allergies has also seen major transformations. While strict allergen avoidance is still the key treatment principle, there is a greater focus on desensitization and tolerance induction by oral and epicutaneous immunotherapy. In addition, specialized hypoallergenic infant formulas for the treatment of infants with cow’s milk allergy have undergone reformulation, including the addition of lactose and probiotics in order to modulate the gut microbiome and early immune responses. Further research is needed to inform the most effective food allergy prevention strategies at the population level. In addition, the wider application of food allergen immunotherapy may provide better health outcomes and improved quality of life for families affected by food allergies.


2020 ◽  
Vol 145 (2) ◽  
pp. AB86
Author(s):  
Alexandria Bozen ◽  
Justin Zaslavsky ◽  
Dara Cohn ◽  
Neha Agnihotri ◽  
Stephannie Davies ◽  
...  

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