Effect of Seasonal Ragweed Exposure on Immunoglobulin E Antiragweed Antibodies in Cultures of Peripheral Mononuclear Cells, Plasma and Nasal Secretions

1985 ◽  
Vol 78 (3) ◽  
pp. 225-232 ◽  
Author(s):  
R.M. Naclerio ◽  
M. Plaut ◽  
N.F. Adkinson ◽  
P.S. Norman, Jr.
Keyword(s):  
Mononuclear Cells ◽  
Immunoglobulin E ◽  
Nasal Secretions ◽  
Peripheral Mononuclear Cells

The stress response in human peripheral mononuclear cells is related to aerobic fitness and Body Mass Index

2019 ◽  
Vol 178 (6) ◽  
Author(s):  
Kelsey C. Bourbeau ◽  
Mattina M. Rosinski ◽  
Taylor M. Szczygiel ◽  
Ryan Pettit-Mee ◽  
Jenna E. Sessions ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Stress Response ◽  
Body Mass ◽  
Aerobic Fitness ◽  
Mononuclear Cells ◽  
Peripheral Mononuclear Cells

scholarly journals Working memory deficits in schizophrenia are associated with the rs34884856 variant and expression levels of the NR4A2 gene in a sample Mexican population: a case control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Elizabeth Ruiz-Sánchez ◽  
Janet Jiménez-Genchi ◽  
Yessica M. Alcántara-Flores ◽  
Carlos J. Castañeda-González ◽  
Carlos L. Aviña-Cervantes ◽  
...  
Keyword(s):  
Working Memory ◽  
Genetic Variants ◽  
Mononuclear Cells ◽  
Memory Performance ◽  
Mexican Population ◽  
High Resolution Melt ◽  
Expression Levels ◽  
Neuropsychiatric Diseases ◽  
Significant Difference ◽  
Peripheral Mononuclear Cells

Abstract Background Cognitive functions represent useful endophenotypes to identify the association between genetic variants and schizophrenia. In this sense, the NR4A2 gene has been implicated in schizophrenia and cognition in different animal models and clinical trials. We hypothesized that the NR4A2 gene is associated with working memory performance in schizophrenia. This study aimed to analyze two variants and the expression levels of the NR4A2 gene with susceptibility to schizophrenia, as well as to evaluate whether possession of NR4A2 variants influence the possible correlation between gene expression and working memory performance in schizophrenia. Methods The current study included 187 schizophrenia patients and 227 controls genotyped for two of the most studied NR4A2 genetic variants in neurological and neuropsychiatric diseases. Genotyping was performed using High Resolution Melt and sequencing techniques. In addition, mRNA expression of NR4A2 was performed in peripheral mononuclear cells of 112 patients and 118 controls. A group of these participants, 54 patients and 87 controls, performed the working memory index of the WAIS III test. Results Both genotypic frequencies of the two variants and expression levels of the NR4A2 gene showed no significant difference when in patients versus controls. However, patients homozygous for the rs34884856 promoter variant showed a positive correlation between expression levels and auditory working memory. Conclusions Our finding suggested that changes in expression levels of the NR4A2 gene could be associated with working memory in schizophrenia depending on patients’ genotype in a sample from a Mexican population.

scholarly journals Transcriptional Expression Profile of Toll Like Receptor 1 - 10 mRNA in Bovine Peripheral Mononuclear Cells in Response to Foot and Mouth Disease Antigens

2012 ◽  
Vol 02 (04) ◽  
pp. 417-425 ◽  
Author(s):  
Sathish Gaikwad ◽  
Sowmya Kumar ◽  
Thimmareddy Prashanth ◽  
Golla Rama Reddy ◽  
Veluvarthy Sanyasi Suryanarayana ◽  
...  
Keyword(s):  
Expression Profile ◽  
Mononuclear Cells ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Toll Like Receptor ◽  
Transcriptional Expression ◽  
Foot And Mouth ◽  
Peripheral Mononuclear Cells
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