Distinction of the Human Basophil Promoting Activity from Human Interleukin-3

1985 ◽  
Vol 77 (1-2) ◽  
pp. 151-154 ◽  
Author(s):  
Beda M. Stadler ◽  
Koichi Hirai ◽  
Kenji Tadokoro ◽  
Alain L. de Weck
Keyword(s):  
Human Basophil ◽  
Interleukin 3

Calreticulin is an interleukin-3-sensitive calcium-binding protein in human basophil leukocytes

Allergy ◽  
2001 ◽  
Vol 56 (1) ◽  
pp. 21-28 ◽  
Author(s):  
M. J. Lyngholm ◽  
H. V. Nielsen ◽  
M. Holm ◽  
P. O. Schiotz ◽  
A. H. Johnsen
Keyword(s):  
Calcium Binding ◽  
Binding Protein ◽  
Calcium Binding Protein ◽  
Human Basophil ◽  
Interleukin 3

The effect of endothelin-1 on human basophil function in vitro

Pneumologie ◽  
2011 ◽  
Vol 65 (S 01) ◽  
Author(s):  
K Cima ◽  
S Blunder ◽  
S Desole ◽  
J Günther ◽  
C Kähler
Keyword(s):  
Human Basophil ◽  
Endothelin 1

Interleukin-3

1995 ◽  
Vol &NA; (541) ◽  
pp. 8
Author(s):  
&NA;
Keyword(s):  
Interleukin 3

scholarly journals Interleukin-3 is significantly more effective than other colony- stimulating factors in long-term maintenance of human bone marrow- derived colony-forming cells in vitro

Blood ◽  
1989 ◽  
Vol 73 (7) ◽  
pp. 1836-1841 ◽  
Author(s):  
M Kobayashi ◽  
BH Van Leeuwen ◽  
S Elsbury ◽  
ME Martinson ◽  
IG Young ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cultured Cells ◽  
Bone Marrow Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Interleukin 3 ◽  
Gm Csf ◽  
Factor G ◽  
Marrow Cells

Abstract Human bone marrow cells cultured for 21 days in the presence of recombinant human interleukin-3 (IL-3) produced up to 28 times more colony-forming cells (CFC) than could be obtained from cultures stimulated with granulocyte colony stimulating factor (G-CSF) or granulocyte-macrophage CSF (GM-CSF). IL-3-cultured cells retained a multipotent response to IL-3 in colony assays but were restricted to formation of granulocyte colonies in G-CSF and granulocyte or macrophage colonies in GM-CSF. Culture of bone marrow cells in IL-3 also led to accumulation of large numbers of eosinophils and basophils. These data contrast with the effects of G-CSF, GM-CSF, and IL-3 in seven-day cultures. Here both GM-CSF and IL-3 amplified total CFC that had similar multipotential colony-forming capability in either factor. G-CSF, on the other hand, depleted IL-3-responsive colony-forming cells dramatically, apparently by causing these cells to mature into granulocytes. The data suggest that a large proportion of IL-3- responsive cells in human bone marrow express receptors for G-CSF and can respond to this factor, the majority becoming neutrophils. Furthermore, the CFC maintained for 21 days in IL-3 may be a functionally distinct population from that produced after seven days culture of bone marrow cells in either IL-3 or GM-CSF.

scholarly journals Characterization of three related murine interleukin-3 surface receptor proteins

1991 ◽  
Vol 266 (7) ◽  
pp. 4151-4158
Author(s):  
D A Stevens ◽  
J Schreurs ◽  
J N Ihle ◽  
W S May
Keyword(s):  
Receptor Proteins ◽  
Interleukin 3 ◽  
Surface Receptor
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