Detection of Shedding of Human Blood Monocyte Fc Receptor during in vitro Culture

1981 ◽  
Vol 66 (2) ◽  
pp. 131-135 ◽  
Author(s):  
Neil E. Kay ◽  
Steven D. Douglas
2001 ◽  
Vol 13 (12) ◽  
pp. 1571-1581 ◽  
Author(s):  
Carmen Sánchez-Torres ◽  
Gina S. García-Romo ◽  
Miguel A. Cornejo-Cortés ◽  
Amaranta Rivas-Carvalho ◽  
Guzmán Sánchez-Schmitz

2001 ◽  
Vol 76 (1-2) ◽  
pp. 59-71 ◽  
Author(s):  
Lars Thiele ◽  
Barbara Rothen-Rutishauser ◽  
Samantha Jilek ◽  
Heidi Wunderli-Allenspach ◽  
Hans P. Merkle ◽  
...  

1998 ◽  
Vol 5 ◽  
pp. 72
Author(s):  
J.R. Powell ◽  
M.E.J. Barratt ◽  
A. Hillebrand ◽  
T.L. Hurst ◽  
G.Nebe von Caron

Blood ◽  
1985 ◽  
Vol 66 (2) ◽  
pp. 298-301
Author(s):  
JA Elias ◽  
P Chien ◽  
KM Gustilo ◽  
AD Schreiber

Interleukin-1 (IL-1) is an important immunoregulatory peptide produced by monocytes and macrophages. Because mononuclear phagocytes are morphologically and functionally heterogeneous, we examined whether they differ in their ability to elaborate IL-1. We used discontinuous Percoll gradients to obtain five density-defined human blood monocyte subpopulations. Unfractionated monocytes and their subsets were compared for their ability to stimulate thymocyte proliferation. Supernatants obtained from the denser monocytes consistently contained more IL-1 activity than did supernatants from the less dense cells. This difference in IL-1 activity was the result of differences in IL-1 elaboration, not the selective production of an inhibitor of IL-1- induced thymocyte proliferation. These data demonstrate that density- defined human monocyte subpopulations differ in their capacity to elaborate IL-1.


Blood ◽  
1985 ◽  
Vol 66 (2) ◽  
pp. 298-301 ◽  
Author(s):  
JA Elias ◽  
P Chien ◽  
KM Gustilo ◽  
AD Schreiber

Abstract Interleukin-1 (IL-1) is an important immunoregulatory peptide produced by monocytes and macrophages. Because mononuclear phagocytes are morphologically and functionally heterogeneous, we examined whether they differ in their ability to elaborate IL-1. We used discontinuous Percoll gradients to obtain five density-defined human blood monocyte subpopulations. Unfractionated monocytes and their subsets were compared for their ability to stimulate thymocyte proliferation. Supernatants obtained from the denser monocytes consistently contained more IL-1 activity than did supernatants from the less dense cells. This difference in IL-1 activity was the result of differences in IL-1 elaboration, not the selective production of an inhibitor of IL-1- induced thymocyte proliferation. These data demonstrate that density- defined human monocyte subpopulations differ in their capacity to elaborate IL-1.


2017 ◽  
Vol 37 (8) ◽  
pp. 1548-1558 ◽  
Author(s):  
Graham D. Thomas ◽  
Anouk A.J. Hamers ◽  
Catherine Nakao ◽  
Paola Marcovecchio ◽  
Angela M. Taylor ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document