Mast Cell Numbers and Passive Cutaneous Anaphylaxis in Irradiated Mice

1977 ◽  
Vol 54 (4) ◽  
pp. 378-381 ◽  
Author(s):  
Brian G. Carter
Keyword(s):  
Mast Cell ◽  
Passive Cutaneous Anaphylaxis ◽  
Cell Numbers

Multinucleate cell angiohistiocytoma: a fibrohistiocytic proliferation with increased mast cell numbers and vascular hyperplasia

2002 ◽  
Vol 29 (4) ◽  
pp. 232-237 ◽  
Author(s):  
◽  
María-Teresa Fernández-Figueras ◽  
Isabel Bielsa ◽  
Betlem Lloveras ◽  
Keyword(s):  
Mast Cell ◽  
Multinucleate Cell ◽  
Cell Numbers

Increased Mast Cell Numbers in the Sclerotic Skin of Porphyria cutanea tarda

Dermatology ◽  
1989 ◽  
Vol 178 (2) ◽  
pp. 75-78 ◽  
Author(s):  
Wakio Torinuki ◽  
Kazuhiro Kudoh ◽  
Hachiro Tagami
Keyword(s):  
Mast Cell ◽  
Porphyria Cutanea Tarda ◽  
Cell Numbers

Testicular serotonin is related to mast cells but not to Leydig cells in the rat

1995 ◽  
Vol 146 (1) ◽  
pp. 15-21 ◽  
Author(s):  
R Aguilar ◽  
F Antón ◽  
C Bellido ◽  
E Aguilar ◽  
F Gaytan
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Leydig Cell ◽  
Leydig Cells ◽  
Interstitial Fluid ◽  
Ventral Prostate ◽  
Adult Rats ◽  
Cell Numbers ◽  
Oestradiol Benzoate ◽  
Testicular Capsule

Abstract Testicular serotonin (5HT) concentrations were determined by HPLC in the testes of rats treated neonatally with oestradiol benzoate (EB) and in adult rats treated with the Leydig cell cytotoxic ethylene dimethane sulphonate (EDS). 5HT concentrations were related to mast cell numbers. EB-treated rats showed an accumulation of mast cells in the testes at 35 and 70 days of age and increased 5HT concentrations in both the interstitial fluid and the testicular capsule, whereas no increases in 5HT concentrations or in the number of mast cells were found for the ventral prostate of these animals. On the contrary, 5HT concentrations were not related to the number of Leydig cells. In EB-treated rats, in which Leydig cells were nearly absent at 35 days of age, 5HT concentrations were significantly increased. Furthermore, EDS-treated rats did not show significant changes in 5HT concentrations, in spite of the elimination of Leydig cells. These data suggest that mast cells are a major source of serotonin in the rat testis. Journal of Endocrinology (1995) 146, 15–21

Rapid increase in mast cell numbers in canine central and peripheral airways

1988 ◽  
Vol 65 (1) ◽  
pp. 445-451 ◽  
Author(s):  
C. R. Turner ◽  
J. Kolbe ◽  
E. W. Spannhake
Keyword(s):  
Mast Cell ◽  
Airway Epithelium ◽  
Time Course ◽  
Isotonic Saline ◽  
Cell Movement ◽  
Cell Number ◽  
Small Airways ◽  
Cell Numbers ◽  
Peripheral Airways ◽  
Cell Counts

In preliminary studies of antigen-induced airway inflammation, we noted an apparent increase in peribronchiolar mast cell number. Experiments were thus undertaken to investigate the nature of this migration of mast cells into the central and peripheral airway epithelium and to determine its time course. The tracheae and small airways of 10 anesthetized mongrel dogs were exposed via a bronchoscope to Ascaris suum antigen (Ag), fMet-Leu-Phe (fMLP), ovalbumin (OVA), and isotonic saline (SAL). In the central airways, all stimuli provoked a significant increase (P less than 0.05) in mast cell numbers at the base of the airway epithelium within 3 h. In the peripheral airways, only Ag aerosol stimulated a significant mast cell increase compared with unexposed tissue. In a second series of experiments, the trachea of seven dogs were exposed to 0.026, 0.26, and 2.6 micrograms of Ag. The tissue was collected at 1, 3, 6, and 10 h after exposure. In these experiments, there was a significant mast cell increase seen within 1 h but it was not dose dependent. By 6-10 h after exposure, mast cell counts were not significantly different from the unexposed condition, which is consistent with the idea that some of the cells either degranulated or migrated into the airway lumen. We conclude that mast cell migration is an acute response that can be demonstrated within 1 h of stimulation with Ag. The observation that nonimmunological stimuli may, in some cases, also stimulate mast cell movement affords the possibility that this process represents a generalized response to airway irritation.

Mast cell numbers in the esophagus are increased in association with specialized intestinal metaplasia

1995 ◽  
Vol 108 (4) ◽  
pp. A159 ◽  
Author(s):  
F. Marinelli ◽  
R. Odze ◽  
G.T. Furuta ◽  
S. Spechler ◽  
B.K. Wershil
Keyword(s):  
Mast Cell ◽  
Intestinal Metaplasia ◽  
Cell Numbers ◽  
Specialized Intestinal Metaplasia

Mast cell numbers in incisional wounds in rat skin as a function of distance, time and treatment

1983 ◽  
Vol 108 (2) ◽  
pp. 179-187 ◽  
Author(s):  
M.A. PERSINGER ◽  
PATRICIA LEPAGE ◽  
J.-P. SIMARD ◽  
G.H. PARKER
Keyword(s):  
Mast Cell ◽  
Rat Skin ◽  
Cell Numbers

Seasonal allergic conjunctivitis is accompanied by increased mast cell numbers in the absence of leucocyte infiltration

1997 ◽  
Vol 27 (9) ◽  
pp. 1060-1066 ◽  
Author(s):  
D. F. ANDERSON ◽  
J. D. A. MACLEOD ◽  
S. M. BADDELEY ◽  
A. S. BACON ◽  
J. I. McGILL ◽  
...  
Keyword(s):  
Mast Cell ◽  
Allergic Conjunctivitis ◽  
Cell Numbers ◽  
Seasonal Allergic Conjunctivitis ◽  
Leucocyte Infiltration

5-hydroxytryptamine content of mast cells, mast cell numbers and body growth

1978 ◽  
Vol 112 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Lennart Enerbäck ◽  
Lennart Mellblom
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Body Growth ◽  
Cell Numbers

scholarly journals The Equine Endometrial Mast Cell during the Puerperal Period: Evaluation of Mast Cell Numbers and Types in Comparison to Other Inflammatory Changes

1997 ◽  
Vol 34 (1) ◽  
pp. 23-30 ◽  
Author(s):  
M. M. Welle ◽  
L. Audigé ◽  
J.-P. Belz
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Immunohistochemical Staining ◽  
Staining Technique ◽  
Cell Types ◽  
Postnatal Period ◽  
Double Labeling ◽  
Tissue Samples ◽  
Cell Numbers ◽  
Significant Difference

Endometrial biopsies of 44 broodmares were histologically examined on days 3, 6, and 9 postpartum. The mares were subdivided into three groups according to the course of the puerperal period. In 29 mares, parturition and expulsion of the placenta was normal, six mares showed dystocia, and in nine mares, the placenta was retained for >2 hours. Tissue samples were evaluated histologically, and the average numbers of granulocytes, lymphocytes, macrophages, siderophages, and mast cells was determined. Protease content of mast cells was examined with a double-enzyme immunohistochemical staining technique, using a histochemical reaction for chloroacetate esterase and fast blue to detect chymase activity and an immunohistochemical staining method with a polyclonal antibody and fast red for the detection of tryptase. Analyzing the cell numbers using the statistical software Statistica, a marked inflammatory reaction was observed in the endometrium postpartum. Although the number of granulocytes decreased during the first 9 days postpartum, the number of lymphocytes, macrophages, and siderophages increased. No significant difference in the number of any of these cell types could be demonstrated in the three different courses of the puerperal period, although the numbers of these cells seemed to be lower in mares with dystocia. In contrast with other cells, no change in the number of endometrial mast cells was observed during the puerperal period, but a significantly lower number were found in the endometrium of mares with retained placenta. The enzyme immunohistochemical double-labeling technique could demonstrate only tryptase-positive mast cells; no chymase activity was detectable in any endometrial mast cells. The number of mast cells detected with the metachromatic staining technique was significantly higher than that detected with double labeling. These results support the hypothesis that a sufficient number of mast cells may be necessary for a normal postnatal period and suggest a mast cell subtype in the equine endometrium that is tryptase and chymase negative.

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