Mitogen-Reactive Lymphocytes in the Embryonic Chicken Thymus in Organ Culture

1974 ◽  
Vol 47 (3) ◽  
pp. 388-399 ◽  
Author(s):  
Jan F. Sällström ◽  
Gunnar V. Alm
1979 ◽  
Vol 21 (3) ◽  
pp. 189-194 ◽  
Author(s):  
MASANOBU SUGIMOTO ◽  
TOMOYOSHI YASUDA ◽  
YASUYUKI EGASHIRA

1977 ◽  
Vol 56 (2) ◽  
pp. 281-292 ◽  
Author(s):  
Masanobu Sugimoto ◽  
Tomoyoshi Yasuda ◽  
Yasuyuki Egashira

Development ◽  
1962 ◽  
Vol 10 (3) ◽  
pp. 389-409
Author(s):  
Honor B. Fell

In earlier work it was found that the addition of excess of vitamin A (10 i.u./ml.) to the culture medium produces drastic changes in embryonic limb-bones and skin in organ culture. The matrix of cartilage (mouse, chick) and bone (mouse) rapidly disappears (Fell & Mellanby, 1952; Fell, Mellanby, & Pelc, 1956) and in the epidermis of skin from 7 to 18-day chick embryos (Fell & Mellanby, 1953; Fell, 1957; Pelc & Fell, 1960) keratinization is immediately arrested and a remarkable mucous metaplasia appears. In a previous paper (Fell & Thomas, 1961) it was shown that when hydrocortisone (7·5 μg./ml.) is added together with vitamin A, resorption of intercellular material is greatly retarded in the explanted limb-bone rudiments. The present experiments were undertaken to see whether the hormone would also inhibit the metaplastic effect produced by vitamin A in the epidermis of embryonic chicken skin in vitro.


1977 ◽  
Vol 56 (2) ◽  
pp. 293-305 ◽  
Author(s):  
Masanobu Sugimoto ◽  
Tomoyoshi Yasuda ◽  
Yasuyuki Egashira

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