IgE Levels and Allergic Skin Reactions in Cancer and Non-cancer Patients

1971 ◽  
Vol 41 (1) ◽  
pp. 141-143 ◽  
Author(s):  
R. Augustin ◽  
K.D. Chandradasa
Keyword(s):  
Cancer Patients ◽  
Skin Reactions ◽  
Allergic Skin

scholarly journals Management of Acute Radiodermatitis in Non-Melanoma Skin Cancer Patients Using Electrospun Nanofibrous Patches Loaded with Pinus halepensis Bark Extract

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2596
Author(s):  
Aikaterini Kyritsi ◽  
Stefanos Kikionis ◽  
Anna Tagka ◽  
Nikolaos Koliarakis ◽  
Antonia Evangelatou ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Skin Cancer ◽  
Cancer Patients ◽  
Pinus Halepensis ◽  
Radiation Therapy Oncology Group ◽  
Bark Extract ◽  
Skin Reactions ◽  
Non Melanoma Skin Cancer ◽  
Patient Reported ◽  
Melanoma Skin

Acute radiodermatitis is the most common side effect in non-melanoma skin cancer patients undergoing radiotherapy. Nonetheless, despite the ongoing progress of clinical trials, no effective regimen has been found yet. In this study, a non-woven patch, comprised of electrospun polymeric micro/nanofibers loaded with an aqueous extract of Pinus halepensis bark (PHBE), was fabricated and clinically tested for its efficacy to prevent radiodermatitis. The bioactivity of the PHBE patch was evaluated in comparison with a medical cream indicated for acute radiodermatitis. Twelve volunteer patients were selected and randomly assigned to two groups, applying either the PHBE patch or the reference cream daily. Evaluation of radiation-induced skin reactions was performed during the radiotherapy period and 1 month afterwards according to the Radiation Therapy Oncology Group (RTOG) grading scale, photo-documentation, patient-reported outcomes (Visual Analog Scale, questionnaire), biophysical measurements (hydration, transepidermal water loss, erythema, melanin), and image analysis. In contrast with the reference product, the PHBE patch showed significant anti-inflammatory activity and restored most skin parameters to normal levels 1 month after completion of radiation therapy. No adverse event was reported, indicating that the application of the PHBE patch can be considered as a safe medical device for prophylactic radiodermatitis treatment.

Haplotype-Based Analysis of Genes Associated With Risk of Adverse Skin Reactions After Radiotherapy in Breast Cancer Patients

2007 ◽  
Vol 69 (3) ◽  
pp. 685-693 ◽  
Author(s):  
Tomo Suga ◽  
Atsuko Ishikawa ◽  
Masakazu Kohda ◽  
Yoshimi Otsuka ◽  
Shigeru Yamada ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Skin Reactions

scholarly journals Allergic Skin Reactions to Anticonvulsant Medications in Patients Receiving Cranial Radiation Therapy

Epilepsia ◽  
1999 ◽  
Vol 40 (3) ◽  
pp. 341-344 ◽  
Author(s):  
Harvey J. Mamon ◽  
Patrick Y. Wen ◽  
Anne C. Burns ◽  
Jay S. Loeffler
Keyword(s):  
Radiation Therapy ◽  
Skin Reactions ◽  
Cranial Radiation ◽  
Allergic Skin

Skin dose assessment with treatment planning system (TPS) and skin reaction evaluation of early breast cancer patients treated via an intraoperative radiation therapy (IORT) device

2018 ◽  
Vol 17 (4) ◽  
pp. 417-421
Author(s):  
Omid Baziar ◽  
Hamid Gholamhosseinian ◽  
Mohammad Naser Forghani
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Planning System ◽  
Treatment Planning System ◽  
Intraoperative Radiation Therapy ◽  
Skin Dose ◽  
Breast Cancer Patients ◽  
Skin Reactions ◽  
Intraoperative Radiation ◽  
Skin Doses

AbstractPurposeTo assess skin dose and incidence of skin reactions in early breast cancer patients treated via Intrabeam™ intraoperative radiation therapy (IORT) device.Materials and methodsIn total, 250 breast cancer patients treated with a single fraction of 20 Gy using 50 kV photon were recruited. The applicator to skin distance (ASD) was measured before the initiation of the radiation and the skin dose in each patient was accordingly calculated based on the treatment planning system (TPS).ResultsThe average skin doses calculated were equal to 7·91, 5·83, 3·96 and 2·14 Gy for 6–10, 10–15, 15–20 and 20–30 mm ASD values, respectively. It is noticeable that the skin doses could be lower than the TPS measurements up to 45%, mostly due to lack of backscatter radiation in breast tissue compared with the full scatter condition in the Zeiss water phantom. Finally, only three patients showed low-grade skin reactions 1 week after IORT. A review of the related literature also revealed the incidence of lower skin complications among patients treated via Intrabeam™ compared with MammoSite™ machine.ConclusionsThe Intrabeam™ TPS did not seem to be very reliable for accurate skin dosimetry. However, breast cancer treatment using Intrabeam™ could result in fewer incidences of skin reactions than MammoSite™ machine.

scholarly journals An evaluation of the skincare management of patients receiving radiotherapy for breast cancer

2019 ◽  
Vol 19 (4) ◽  
pp. 365-369 ◽  
Author(s):  
Leona McAlinden ◽  
Andrea Mullan ◽  
Paul Shepherd
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Best Practice ◽  
Management Strategies ◽  
Breast Cancer Patients ◽  
Skin Reactions ◽  
Prophylactic Measures ◽  
Radiation Induced ◽  
Guidance Needs ◽  
The Uk

AbstractAim:Breast cancer patients experience skin reactions during radiotherapy. Radiation-induced skin reactions can result in treatment delivery being interrupted. The aim of this paper is to evaluate the skincare management of patients receiving radiotherapy for breast cancer in order to inform best practice.Method:A literature search was undertaken using USearch and HONNI in support of the first-hand evidence gained from the supervised on-treatment review of patients receiving radiotherapy for breast cancer.Results:There is evidence to suggest that the skincare advice given to patients varies widely between departments in the UK with many not following nationally recommended guidelines. Studies demonstrate that there are ways to reduce skin reactions and that there are a range of effective management strategies being adopted. Prophylactic skincare has been explored to improve the resilience of the skin prior to commencing radiotherapy.Findings:Further investigation is required in order to clearly establish the optimum national skincare management for breast cancer patients. More studies are required to test the effectiveness and viability of prophylactic measures. Skincare guidance needs to be robustly developed and effectively promoted by therapeutic radiographers for radiotherapy patients to benefit from reduced, radiation-induced, skin reactions.

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