Clinical Evaluation of 5-(3,3-Dimethyl-1-Triazeno) Imidazole-4-Carboxamide in Malignant Melanoma and Other Neoplasms: Comparison of Twice-weekly and Daily Administration Schedules

Oncology ◽  
1971 ◽  
Vol 25 (3) ◽  
pp. 225-233 ◽  
Author(s):  
J.A. Gottlieb ◽  
A.A. Serpick
Keyword(s):  
Malignant Melanoma ◽  
Clinical Evaluation ◽  
Daily Administration ◽  
Other Neoplasms ◽  
Administration Schedules

A Clinical Evaluation of a Delayed Release Preparation of Metformin

1973 ◽  
Vol 1 (6) ◽  
pp. 551-556 ◽  
Author(s):  
I W Campbell ◽  
B F Clarke ◽  
L J P Duncan
Keyword(s):  
Side Effects ◽  
Clinical Evaluation ◽  
Therapeutic Response ◽  
Daily Administration ◽  
Diabetic Patients ◽  
Delayed Release ◽  
Release Preparation ◽  
Sulphonylurea Treatment

The efficacy of a delayed release preparation of metformin (‘Obin’)† has been evaluated in 60 diabetic patients either obese and uncontrolled by diet alone or true primary or secondary failures to sulphonylurea treatment. The results show no difference in the therapeutic response between single and twice daily administration of ‘Obin’; likewise there was no difference in frequency of side-effects.

Clinical Evaluation of Cutaneous Malignant Melanoma with Histologically Involved Lymph Node Metastases

1991 ◽  
Vol 18 (10) ◽  
pp. 592-597 ◽  
Author(s):  
Tsuneki Sugihara ◽  
Tetsunori Yoshida ◽  
Takehiko Ohura ◽  
Akira Ohkawara ◽  
Masanobu Kumakiri
Keyword(s):  
Lymph Node ◽  
Malignant Melanoma ◽  
Clinical Evaluation ◽  
Lymph Node Metastases ◽  
Cutaneous Malignant Melanoma ◽  
Node Metastases

scholarly journals Clinical Evaluation of Interferons in Malignant Melanoma

1990 ◽  
Vol 95 (6) ◽  
pp. S185-S187 ◽  
Author(s):  
G.R. McLeod ◽  
D.B. Thomson ◽  
P. Hersey
Keyword(s):  
Malignant Melanoma ◽  
Clinical Evaluation

scholarly journals Screening of malignant melanoma (MM) by miRNA: preliminary data on incidence after initial clinical evaluation

2016 ◽  
Vol 27 ◽  
pp. iv90
Author(s):  
M. Occelli ◽  
C. Cauhi ◽  
G. Sciancalepore ◽  
C. Lo Nigro ◽  
M. Rovera ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Clinical Evaluation ◽  
Preliminary Data ◽  
Initial Clinical Evaluation

Clinical evaluation of 5-S-cysteinyldopa testing using a new and optimized detection system as a tumour marker for malignant melanoma

2002 ◽  
Vol 12 (5) ◽  
pp. 471-477 ◽  
Author(s):  
T. Meyer ◽  
A. Hauschild ◽  
A. Kromminga ◽  
J. Hartleb ◽  
R. Arndt ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Clinical Evaluation ◽  
Detection System ◽  
Tumour Marker

Clinical evaluation of metastases of malignant melanoma imaging with 99Tcm-glutathione and 99Tcm-anti-melanoma antibody

1995 ◽  
Vol 16 (11) ◽  
pp. 927-935 ◽  
Author(s):  
Y. DUMAN ◽  
Z. BURAK ◽  
M. T. ERCAN ◽  
A. DIRLIK ◽  
B. Ç. BILKAY ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Clinical Evaluation

Human Neurofibromas in Co-Culture with Mouse Neurons

1982 ◽  
Vol 40 ◽  
pp. 194-195
Author(s):  
R.L. Martuza ◽  
T. Liszczak ◽  
A. Okun ◽  
T-Y Wang
Keyword(s):  
Schwann Cell ◽  
Schwann Cells ◽  
Genetic Disorder ◽  
Cranial Nerves ◽  
Sympathetic Nerves ◽  
Acoustic Neuromas ◽  
Spinal Roots ◽  
Neural Crest Origin ◽  
Multiple Abnormalities ◽  
Other Neoplasms

Neurofibromatosis (NF) is an autosomal dominant genetic disorder with a prevalence of 1/3,000 births. The NF mutation causes multiple abnormalities of various cells of neural crest origin. Schwann cell tumors (neurofibromas, acoustic neuromas) are the most common feature of neurofibromatosis although meningiomas, gliomas, and other neoplasms may be seen. The schwann cell tumors commonly develop from the schwann cells associated with sensory or sympathetic nerves or their ganglia. Schwann cell tumors on ventral spinal roots or motor cranial nerves are much less common. Since the sensory neuron membrane is known to contain a mitogenic factor for schwann cells, we have postulated that neurofibromatosis may be due to an abnormal interaction between the nerve and the schwann cell and that this interaction may be hormonally modulated. To test this possibility a system has been developed in which an enriched schwannoma cell culture can be obtained and co-cultured with pure neurons.

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