Is Obesity Associated with a Survival Advantage in Patients Starting Peritoneal Dialysis?

2009 ◽  
pp. 124-131 ◽  
Author(s):  
Renée de Mutsert ◽  
Diana C. Grootendorst ◽  
Elisabeth W. Boeschoten ◽  
Friedo W. Dekker ◽  
Raymond T. Krediet
Keyword(s):  
Peritoneal Dialysis ◽  
Survival Advantage

scholarly journals Survival advantage of hemodialysis relative to peritoneal dialysis in patients with end-stage renal disease and congestive heart failure

2011 ◽  
Vol 80 (9) ◽  
pp. 970-977 ◽  
Author(s):  
Florence Sens ◽  
Anne-Marie Schott-Pethelaz ◽  
Michel Labeeuw ◽  
Cyrille Colin ◽  
Emmanuel Villar
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Peritoneal Dialysis ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Survival Advantage ◽  
Stage Renal Disease ◽  
End Stage

Is There a Survival Advantage in Asian Peritoneal Dialysis Patients?

2003 ◽  
Vol 26 (5) ◽  
pp. 363-372 ◽  
Author(s):  
Philip K.-T. Li ◽  
K.M. Chow ◽  
C.C. Szeto
Keyword(s):  
Peritoneal Dialysis ◽  
Survival Data ◽  
Dialysis Patient ◽  
Patient Survival ◽  
Disease Patient ◽  
Peritoneal Dialysis Patient ◽  
Research Literature ◽  
Survival Advantage ◽  
Dialysis Adequacy ◽  
Epidemiological Surveys

Over the last decade, epidemiological surveys and qualitative research literature have demonstrated and validated a better survival in the Asian peritoneal dialysis population. This review summarizes the current understanding of Asian peritoneal dialysis patient survival and attempts to scrutinize the supposed survival advantage of this population group. We outlined the published peritoneal dialysis survival data from a literature search, with reference to dialysis patient cohorts from 1983 through 2002 for prevalent cases and 1980 through 2002 for incident patients. Two-year and 5-year patient survival rates in excess of 80% and 60% respectively were demonstrated in Asian countries, which compared favorably with the CANUSA, ADEMEX and most Caucasian series. Better end-stage renal disease patient survival is apparent despite a dialysis adequacy disadvantage, for reasons yet to be identified. As is the case of other racial disparities in medical care, such a difference is a product of more than biological differences and include budgetary barrier, health care system and geographic variation, physician bias and statistical pitfalls. Particular efforts should therefore be made to explore the underlying reason(s) for the Asian peritoneal dialysis patient survival advantage. Alternative approach and guidelines to peritoneal dialysis delivery in Asia might be warranted.

Survival Advantage of Normal Weight in Peritoneal Dialysis Patients

Renal Failure ◽  
2011 ◽  
Vol 33 (10) ◽  
pp. 964-968 ◽  
Author(s):  
Hua Zhou ◽  
Li Cui ◽  
GeYa Zhu ◽  
YaPing Jiang ◽  
XiaoXia Gao ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Normal Weight ◽  
Survival Advantage ◽  
Dialysis Patients

scholarly journals 2005 Guidelines on targets for solute and fluid removal in adults being treated with chronic peritoneal dialysis: 2019 Update of the literature and revision of recommendations

2020 ◽  
Vol 40 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Neil Boudville ◽  
Thyago Proença de Moraes
Keyword(s):  
Peritoneal Dialysis ◽  
Residual Renal Function ◽  
Survival Advantage ◽  
Fluid Removal ◽  
Hand Search ◽  
Significant Survival ◽  
Intervention Trials ◽  
Randomised Controlled ◽  
Small Solute ◽  
Solute Clearance

Background: The International Society for Peritoneal Dialysis guidelines for small solute clearance and fluid removal in peritoneal dialysis (PD) were published in 2005. The aim of this article is to update those guidelines by reviewing the literature that supported those guidelines and examining publications since then. Methods: An extensive search of publications was performed through electronic databases and a hand search through reference lists from the existing guideline and selected articles. Results: There have been no prospective intervention trials to inform the area of small solute clearance in PD since the publication of the original guideline in 2005. The trials to date are largely limited to a few prospective cohort studies and retrospective studies. These have, however, consistently demonstrated that residual renal function (RRF) is more often associated with patient outcome than peritoneal clearance. One of the few randomised controlled trials performed in this area does suggest that a weekly Kt/ V of 2.27 ± 0.02 provides no statistically significant survival advantage over a weekly Kt/ V of 1.80 ± 0.02. The lower limit of Kt/ V is unknown but there is weak evidence to suggest that anuric people doing PD should have a weekly Kt/ V of at least 1.7. Conclusions: There continues to be very poor evidence in the area of small solute clearance and fluid removal in PD. The evidence that exists suggests that RRF is more important than peritoneal clearance and that there appears to be no survival advantage in aiming for a weekly Kt/ V >1.70.

scholarly journals Initial survival advantage of peritoneal dialysis relative to haemodialysis

2002 ◽  
Vol 17 (1) ◽  
pp. 112-117 ◽  
Author(s):  
James G. Heaf ◽  
Hans Løkkegaard ◽  
Melvin Madsen
Keyword(s):  
Peritoneal Dialysis ◽  
Survival Advantage

scholarly journals Survival advantage of planned haemodialysis over peritoneal dialysis: a cohort study

2018 ◽  
Vol 33 (8) ◽  
pp. 1411-1419 ◽  
Author(s):  
Alicia Thiery ◽  
François Séverac ◽  
Thierry Hannedouche ◽  
Cecile Couchoud ◽  
Van Huyen Do ◽  
...  
Keyword(s):  
Cohort Study ◽  
Peritoneal Dialysis ◽  
Survival Advantage

scholarly journals Superior Patient Survival for Continuous Ambulatory Peritoneal Dialysis Patients Treated with a Peritoneal Dialysis Fluid with Neutral pH and Low Glucose Degradation Product Concentration (Balance)

2005 ◽  
Vol 25 (3) ◽  
pp. 248-255 ◽  
Author(s):  
Ho Yung Lee ◽  
Hyeong Cheon Park ◽  
Bo Jeung Seo ◽  
Jun Young Do ◽  
Sung Ro Yun ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Medical Care ◽  
Cox Regression ◽  
Age Distribution ◽  
Survival Advantage ◽  
Free Survival ◽  
Technique Survival ◽  
Risk Of Death ◽  
Neutral Ph ◽  
Peritoneal Dialysis Fluid

Background In recent years, laboratory and clinical research has suggested the need for peritoneal dialysis fluids (PDFs) that are more biocompatible than the conventional PDFs commonly used today. Bioincompatibility of PDF has been attributed to low pH, lactate, glucose, glucose degradation products (GDPs), and osmolality. PDFs with neutral pH and low GDPs are now available commercially. In vitro and early clinical studies suggest that these solutions are indeed more biocompatible but, as of now, there is no evidence that their use improves patient outcome. Methods Using a dedicated database of over 2000 patients treated with PD in Korea, we were able to conduct a retrospective observational study comparing outcomes for incident continuous ambulatory PD patients treated with a standard, conventional, heat-sterilized PDF to the outcomes for patients treated with a novel, low GDP, neutral-pH PDF prepared in a dual-compartment, double-bag PD system (Balance; Fresenius Medical Care, St. Wendel, Germany). In an intention-to-treat analysis, patient and technique survival, peritonitis-free survival, and peritonitis rates were compared in 611 patients treated with Balance for up to 30 months and 551 patients with a standard PDF (stay·safe; Fresenius Medical Care) treated in the same era and with equivalent follow-up. Results The patients were well matched for most relevant characteristics except older age distribution for the patients treated with the standard PDF. Patients treated with Balance had significantly superior survival compared to those treated with the standard PDF (74% vs 62% at 28 months, p = 0.0032). In a multivariate Cox regression model including age, diabetes, and gender, the survival advantage persisted (relative risk of death for Balance 0.75, 95% confidence interval 0.56 – 0.99, p = 0.0465). Modality technique survival was similar in Kaplan–Meier analysis for both PDFs. No differences were detected in peritonitis-free survival or in peritonitis rates between the two solutions. Conclusion This study, for the first time, suggests that treatment with a novel biocompatible PDF with low GDP concentration and neutral pH confers a significant survival advantage. The exact mechanisms for such a survival advantage cannot be determined from this study. The usual criticisms of observational studies apply and the results reported here strongly warrant the undertaking of appropriately designed, randomized, controlled clinical trials.

Scanning Electron Microscopy of Staphylococcus Epidermidis Adherence to Continuous Ambulatory Peritoneal Dialysis Catheters

1985 ◽  
Vol 43 ◽  
pp. 520-521
Author(s):  
William J. Lamoreaux ◽  
David L. Smalley ◽  
Larry M. Baddour ◽  
Alfred P. Kraus
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Peritoneal Dialysis ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Staphylococcus Epidermidis ◽  
Sterile Saline ◽  
Intravascular Devices ◽  
Capd Patient ◽  
Scanning Electron

Infections associated with the use of intravascular devices have been documented and have been reported to be related to duration of catheter usage. Recently, Eaton et al. reported that Staphylococcus epidermidis may attach to silastic catheters used in continuous ambulatory peritoneal dialysis (CAPD) treatment. The following study presents findings using scanning electron microscopy (SEM) of S. epidermidis adherence to silastic catheters in an in vitro model. In addition, sections of polyvinyl chloride (PVC) dialysis bags were also evaluated by SEM.The S. epidermidis strain RP62A which had been obtained in a previous outbreak of coagulase-negative staphylococcal sepsis at local hospitals was used in these experiments. The strain produced surface slime on exposure to glucose, whereas a nonadherent variant RP62A-NA, which was also used in these studies, failed to produce slime. Strains were grown overnight on blood agar plates at 37°C, harvested from the surface and resuspended in sterile saline (0.85%), centrifuged (3,000 rpm for 10 minutes) and then washed twice in 0.1 M phosphate-buffered saline at pH 7.0. Organisms were resuspended at a concentration of ca. 106 CFU/ml in: a) sterile unused dianeal at 4.25% dextrose, b) sterile unused dianeal at 1.5% dextrose, c) sterile used dialysate previously containing 4.25% dextrose taken from a CAPD patient, and d) sterile used dialysate previously containing 1.5% dextrose taken from a CAPD patient.

Sign in / Sign up

Export Citation Format

Share Document