Effect of Balanced Amino Acid Solution on Protein Metabolism after Surgery

1990 ◽  
Vol 17 (2) ◽  
pp. 100-103
Author(s):  
J. Figueras ◽  
E. Ramos ◽  
J.M. Llop ◽  
N. San-Juan ◽  
J. Marti
Keyword(s):  
Amino Acid ◽  
Acid Solution ◽  
Protein Metabolism ◽  
Amino Acid Solution

Intravenous Alimentation and Insensible Water Loss in Low-Birth- Weight Infants

PEDIATRICS ◽  
1979 ◽  
Vol 63 (4) ◽  
pp. 543-546
Author(s):  
Keith H. Marks ◽  
Timothy P. Farrell ◽  
Zvi Friedman ◽  
M. Jeffrey Maisels
Keyword(s):  
Amino Acid ◽  
Acid Solution ◽  
Water Loss ◽  
Caloric Intake ◽  
Constant Infusion ◽  
Fat Emulsion ◽  
Low Birth Weight Infants ◽  
Amino Acid Solution ◽  
Intravenous Fat Emulsion ◽  
Multiple Measurements

Insensible water loss (IWL) was measured in six premature infants, betWeen 4 and 21 days of age, by continuous weight monitoring on an electronic balance inside an incubator. Multiple measurements of IWL were made during the sequential infusion of 10% dextrose in 0.225% NaCl, 10% dextrose-amino acid solution, or 10% dextrose-amino acid and a commercial intravenous fat emulsion. Each solution was administered for three hours by constant infusion through a scalp vein needle. The order of the infusion was random and a 30-to 60-minute infusion with 5% dextrose water was given between each solution. During the infusion of 10% dextrose in 0.225% NaCl and 10% dextrose + amino acid solution, IWL was 1.0 ± 0.8 gm/kg/ hr and 1.1 ± 0.8 gm/kg/hr, respectively. In contrast, IWL increased significantly to 1.6 ± 0.7 gni/kg/hr when additional calories were given using the 10% dextrose-amino acid with the intravenous fat emulsion (P < .005). There was a positive correlation between caloric intake and IWL. These data suggest that parenteral nutrition solutions with intravenous fat emulsion are rapidly metabolized and the increase in IWL is probably secondary to an increase in thermogenesis.

Effects of plasma amino acid and hormone levels on renal hemodynamics in humans

1988 ◽  
Vol 255 (3) ◽  
pp. F444-F449 ◽  
Author(s):  
P. Castellino ◽  
C. Giordano ◽  
A. Perna ◽  
R. A. DeFronzo
Keyword(s):  
Growth Hormone ◽  
Amino Acid ◽  
Acid Solution ◽  
Growth Hormone Secretion ◽  
Renal Hemodynamics ◽  
Time Sequence ◽  
Plasma Amino Acid ◽  
Base Line ◽  
Amino Acid Solution ◽  
Hormone Levels

The effect of plasma amino acid and hormone (insulin, glucagon, and growth hormone) levels on renal hemodynamics was studied in 18 healthy subjects. The following four protocols were employed: study 1, a balanced amino acid solution was infused for 3 h to increase plasma amino acid concentrations two to three times base line; study 2, the same amino acid solution was infused with somatostatin (SRIF) and infusions of insulin, glucagon, and growth hormone were concomitantly administered to replace the time sequence of increase in peripheral concentrations of these hormones as observed during study 1; study 3, the same amino acid infusion was administered with SRIF plus infusions of insulin, glucagon, and growth hormone to maintain plasma hormone concentrations constant at the basal level; study 4, SRIF was infused with insulin, glucagon, and growth hormone to reproduce the time sequence of increase of these hormones as observed in study 1; amino acids were not infused in this study. During study 1, glomerular filtration rate (GFR) and renal plasma flow (RPF) rose by 19 and 21%, respectively. During study 2 both the time sequence of and magnitude of rise in GFR and in RPF were similar to the changes observed during study 1. In studies 3 and 4 neither RPF nor GFR changed significantly from base line. These results indicate that 1) hyperaminoacidemia stimulates insulin/glucagon/growth hormone secretion and causes a modest rise in GFR and RPF; and 2) if hyperaminoacidemia is created while maintaining basal hormone levels constant or if plasma insulin/glucagon/growth hormone levels are increased while maintaining the plasma amino acid concentration at basal levels, neither RPF nor GFR rise.(ABSTRACT TRUNCATED AT 250 WORDS)

Therapy of myocardial infarction with metabolic agents

1986 ◽  
Vol 67 (5) ◽  
pp. 325-328
Author(s):  
A. E. Vtorov ◽  
L. A. Leshchinsky ◽  
L. T. Pimenov
Keyword(s):  
Myocardial Infarction ◽  
Amino Acid ◽  
Connective Tissue ◽  
Acid Solution ◽  
Anabolic Steroid ◽  
Amino Acid Solution ◽  
Complex Therapy ◽  
Hospital Rehabilitation ◽  
Tissue Metabolites

The aim of the present work was to study in dynamics the concentration of connective tissue metabolites (free and peptide-bound oxyproline) in patients with myocardial infarction at different stages of in-hospital rehabilitation when using metabolic agents as part of complex therapy: free crystalline amino acid solution - alvesin-nova (GDR) in combination with the anabolic steroid retabolol.

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