Short-Term Low Calorie Diet Intervention Reduces Serum Advanced Glycation End Products in Healthy Overweight or Obese Adults

2009 ◽  
Vol 54 (3) ◽  
pp. 197-201 ◽  
Author(s):  
Alejandro Gugliucci ◽  
Kazuhiko Kotani ◽  
Jennifer Taing ◽  
Yukiyo Matsuoka ◽  
Yoshiko Sano ◽  
...  
Keyword(s):  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Short Term ◽  
Obese Adults ◽  
Low Calorie ◽  
Diet Intervention ◽  
Low Calorie Diet ◽  
Glycation End Products ◽  
End Products ◽  
Calorie Diet

scholarly journals Adding Short-Term Interval Exercise to a Low-Calorie Diet Favorably Influences Appetite in Obese Adults

2018 ◽  
Vol 50 (5S) ◽  
pp. 225
Author(s):  
Emily M. Heiston ◽  
Nicole M. Gilbertson ◽  
Natalie Z.M. Eichner ◽  
Julian M. Gaitan ◽  
Monique E. Francois ◽  
...  
Keyword(s):  
Short Term ◽  
Obese Adults ◽  
Low Calorie ◽  
Interval Exercise ◽  
Low Calorie Diet ◽  
Calorie Diet

Decreased Formation of Advanced Glycation End-Products in Peritoneal Fluid by Carnosine and Related Peptides

2007 ◽  
Vol 27 (1) ◽  
pp. 86-89 ◽  
Author(s):  
Mohamed-Saiel Saeed Alhamdani ◽  
Hasan Fayadh Al-Azzawie ◽  
Fawzi K.H. Abbas
Keyword(s):  
Advanced Glycation End Products ◽  
Collagen Type Iv ◽  
Advanced Glycation ◽  
Short Term ◽  
Fluorescence Spectrophotometry ◽  
Age Related ◽  
Short Term Exposure ◽  
Glycation End Products ◽  
End Products ◽  
Related Compounds

Background Formation of advanced glycation end-products (AGEs) is a major problem in uremic patients treated with peritoneal dialysis (PD). Application of additives with known anti-glycosylation properties to PD fluid may be beneficial in minimizing the formation of AGEs. This study aimed to evaluate the effect of carnosine and its related peptides homocarnosine and anserine against the formation of AGEs in PD fluid. Methods PD solutions (1.5% dextrose) were incubated with human serum albumin (HSA) or collagen (type IV) with or without 10 mmol/L of each of carnosine, anserine, homo-carnosine, histidine, and aminoguanidine. The formation of AGEs was followed by fluorescence spectrophotometry at weekly intervals for 7 weeks. For the determination of the acute effect of carnosine and related compounds, HSA and collagen were incubated with 4.25% dextrose PD solutions for 24 hours, followed by incubation with 20 mmol/L of carnosine and related compounds for another 24 hours. The rate of AGE formation was monitored by fluorescence spectrophotometry. Results Carnosine and related compounds showed effective regression in AGE formation in both types of proteins in both long- and short-term exposure to PD fluids at a rate of effectiveness of the order of carnosine > homocarnosine > anserine, aminoguanidine > histidine in long-term exposure, and homocarnosine > carnosine > aminoguanidine > anserine > histidine in short-term exposure. Conclusion Carnosine and related peptides could suppress the formation of AGEs initiated by PD fluid. This observation may provide a new therapeutic approach for the prevention and treatment of the AGE-related complications in PD patients.

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