Skin Care in the NICU Patient: Effects of Wipes versus Cloth and Water on Stratum Corneum Integrity

Neonatology ◽  
2009 ◽  
Vol 96 (4) ◽  
pp. 226-234 ◽  
Author(s):  
Marty Visscher ◽  
Mauricio Odio ◽  
Teresa Taylor ◽  
Tamina White ◽  
Shelly Sargent ◽  
...  
Keyword(s):  
Cosmetics ◽  
2018 ◽  
Vol 5 (4) ◽  
pp. 64
Author(s):  
Pavel Mokrejš ◽  
Jana Pavlačková ◽  
Dagmar Janáčová ◽  
Matouš Huťťa

Although keratin hydrolysates (KH) are added to skin care agents, detailed studies on the moisturising effects of KH are lacking. The aim of this study is to test whether adding KH into an ointment base (OB) heighten hydration of the skin and diminish transepidermal loss of water (TEWL). Formulations containing 2%, 4%, and 6% of KH (based on OB weight) were prepared. Hydration, TEWL and skin pH were measured; intervals of measurements were as follows: 1, 2, 3, 4, 24 and 48 h. Testing was carried out on 10 men. In terms of hydration, supplementing the OB with 2% KH is optimal, as an 11–19% increase occurs in hydration of stratum corneum (SC). All the formulations with added KH as tested caused TEWL to decline after application. Keratin hydrolysate makes for an excellent occlusive; adding it to OB results in a 30–50% reduction in TEWL after application. KH functions as a humectant as well, as it helps to bind water from the lower layers of the epidermis to the SC. Formulations with additions of 2–6% of KH were stable in structure and did not cause phase separation even after 6 months storage.


1999 ◽  
Vol 33 (1) ◽  
pp. 16-26 ◽  
Author(s):  
Junichi Koyama ◽  
Jotaro Nakanishi ◽  
Junko Sato ◽  
Junko Nomura ◽  
Yumiko Suzuki ◽  
...  
Keyword(s):  

1993 ◽  
Vol 27 (3) ◽  
pp. 193-205 ◽  
Author(s):  
Toshiyuki Suzuki ◽  
Jun-ichi Fukasawa ◽  
Hidetaka Iwai ◽  
Ichiro Sugai ◽  
Osamu Yamashita ◽  
...  

2013 ◽  
Vol 32 (2S) ◽  
pp. S30-S32 ◽  
Author(s):  
Paul Horowitz ◽  
Renee McLeod ◽  
Lawrence Eichenfield ◽  
Joseph Fowler ◽  
Peter Elias

2017 ◽  
Vol 57 (1) ◽  
pp. 35
Author(s):  
Tsutomu Fujimura ◽  
Kyoko Shima ◽  
Yuki Miyauchi ◽  
Mitsuyuki Hotta ◽  
Hiroshi Hashimoto ◽  
...  

Background Although understanding the stratum corneum (SC) of infant skin is important to avoid skin diseases such as atopic dermatitis, there has been no such investigation in Indonesian infants to date.Objective  To obtain a basic knowledge of SC characteristics in Indonesian infants in order to develop methods for infant-specific skin care and to prevent dermatitis and infection.Methods Seventy-two healthy, full term infants aged 1 to 24 months who were native Indonesians residing in Jakarta were enrolled in this study. Some of the mothers were also enrolled in the study as adults (n=30). Transepidermal water loss (TEWL) and hydration of the SC (capacitance) on the thigh, buttock, and upper arm were measured after sufficient acclimation in an air-conditioned room, in both infants and mothers. Results The SC hydration was significantly higher in infants than adults at all sites measured, including the buttocks, which is a diaper area. Infant TEWL values were also significantly higher than in adults at all sites. Hydration of the SC and TEWL values showed no significant correlation with age of infant for any site. The SC hydration and TEWL values of Indonesian infants did not decrease to adult values within 24 months, which indicates that the SC characteristics in infants continue to develop after 24 months of age.Conclusion  Indonesian infants aged 0-24 months have significantly higher SC hydration and TEWL values than Indonesian mothers. However, infant age has no correlation to SC hydration or to TEWL values.


2020 ◽  
pp. 138-144
Author(s):  
O. V. Svetlova ◽  
I. V. Gurieva ◽  
A. V. Voronin ◽  
L. S. Savchenko

The feet have an increased load, they are often injured, especially with diabetes. Because of the violation of innervation, patients do not notice minor injuries: abrasions, bruises, cracks, cuts. Because of the circulatory disorders associated with diabetes, the protective function of tissues decreases, and the smallest injury can lead to the formation of a long-term wound that does not heal, which turns into an ulcer when infected. Despite advances in the study of the pathogenesis of diabetes and its complications, diabetic foot ulcers are difficult to treat, can recur, and lead to amputations of the lower limbs. The main reason for pathological dryness of the foot skin in diabetes is dysfunction of the sweat glands of the skin of feet due to diabetic neuropathy. Regular skin care with specially selected products can help restore and improve the barrier function of the skin, as well as increase the moisture level of the stratum corneum. Adequate skin hydration reduces itching and the risk of infection if the skin is damaged. In most patients with diabetes, conventional cosmetics slowly eliminate dry skin of the feet. In addition, traditional remedies contain a large amount of oils and can cause unpleasant sensations, which often causes rejection of their use. In patients with DM, it is desirable to use drugs that quickly and effectively eliminate dryness and cracks. Treatment of dry skin is indicated as a prevention of diabetic foot syndrome. Taking into account the fact that the skin of patients with diabetes mellitus has a low level of humidity, we recommend daily care using moisturizing or nourishing creams or lotions. Some studies have confirmed that the use of external dry skin care products containing dexpanthenol improves the protective function of the skin, increasing the hydration of the stratum corneum.


Biomedicines ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1868
Author(s):  
Michal Szczepanczyk ◽  
Tautgirdas Ruzgas ◽  
Fredrika Gullfot ◽  
Anna Gustafsson ◽  
Sebastian Björklund

The generation of reactive oxygen species presents a destructive challenge for the skin organ and there is a clear need to advance skin care formulations aiming at alleviating oxidative stress. The aim of this work was to characterize the activity of the antioxidative enzyme catalase in keratinocytes and in the skin barrier (i.e., the stratum corneum). Further, the goal was to compare the activity levels with the corresponding catalase activity found in defatted algae biomass, which may serve as a source of antioxidative enzymes, as well as other beneficial algae-derived molecules, to be employed in skin care products. For this, an oxygen electrode-based method was employed to determine the catalase activity and the apparent kinetic parameters for purified catalase, as well as catalase naturally present in HaCaT keratinocytes, excised stratum corneum samples collected from pig ears with various amounts of melanin, and defatted algae biomass from the diatom Phaeodactylum tricornutum. Taken together, this work illustrates the versatility of the oxygen electrode-based method for characterizing catalase function in samples with a high degree of complexity and enables the assessment of sample treatment protocols and comparisons between different biological systems related to the skin organ or algae-derived materials as a potential source of skin care ingredients for combating oxidative stress.


2020 ◽  
Vol 26 (4) ◽  
pp. 455-464
Author(s):  
Koji Mizukoshi ◽  
Takahiro Arakawa ◽  
Kohji Mitsubayashi

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