Age-Related Elevation of Lipid Peroxidation Products: Diminution of Superoxide Dismutase Activity in the Central Nervous System of Rats

Gerontology ◽  
1991 ◽  
Vol 37 (6) ◽  
pp. 305-309 ◽  
Author(s):  
Achla Gupta ◽  
Mahdi Hasan ◽  
Ramesh Chander ◽  
Narinder K. Kapoor
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Superoxide Dismutase ◽  
Nervous System ◽  
Superoxide Dismutase Activity ◽  
Lipid Peroxidation Products ◽  
Age Related ◽  
The Central Nervous System

Age-related changes in lipid peroxidation in various structures of the central nervous system

2005 ◽  
Vol 31 (2) ◽  
pp. 214-220
Author(s):  
I. A. Volchegorskii ◽  
S. E. Shemyakov ◽  
I. B. Telesheva ◽  
N. V. Malinovskaya ◽  
V. V. Turygin
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Age Related ◽  
The Central Nervous System ◽  
Age Related Changes

Superoxide dismutase in the central nervous system of Torpedo marmorata

1983 ◽  
Vol 2 (4) ◽  
pp. 343-347 ◽  
Author(s):  
F.A. Pisanti ◽  
S. Frascatore ◽  
E. Aloj Totaro ◽  
E. Vuttariello
Keyword(s):  
Central Nervous System ◽  
Superoxide Dismutase ◽  
Nervous System ◽  
Torpedo Marmorata ◽  
The Central Nervous System

scholarly journals Clinical and biochemical predictors of neurological disorders

2020 ◽  
Vol 4 (35) ◽  
pp. 34-39
Author(s):  
I. Yu. Serikova ◽  
G. I. Shumacher ◽  
E. N. Vorobyova ◽  
I. A. Batanina ◽  
R. I. Vorobyov
Keyword(s):  
Lipid Peroxidation ◽  
Central Nervous System ◽  
Nervous System ◽  
Neurological Disorders ◽  
Protein S ◽  
Nerve Tissue ◽  
S 100 ◽  
The Central Nervous System ◽  
Peroxidation Processes ◽  
The City

The aim of this study is to identify clinical and biochemical predictors of neurological disorders in adolescents who have suffered mild perinatal damage of the central nervous system. We examined 120 adolescents (62 girls and 58 boys) aged 13–16 years, who were hospitalized in the city Children’s Neurological Department. It was found that adolescents with perinatal lesions of the central nervous system, activated lipid peroxidation processes and revealed an increase in the concentration of protein S 100, which in the future could lead to the development of neurodegeneration processes. In addition, a positive correlation between the lipid peroxidation processes nd the concentration of the nerve tissue damage marker was revealed. The results indicate that the level of neurospecific protein — protein S 100, parameters of the oxidant‑antioxidant system, perinatal factors can be used as predictors of chronic nervous tissue processes.

scholarly journals Antioxidant Defense Mechanisms in Erythrocytes and in the Central Nervous System

Antioxidants ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 46 ◽  
Author(s):  
Rafael Franco ◽  
Gemma Navarro ◽  
Eva Martínez-Pinilla
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Defense Mechanisms ◽  
Antioxidant Defense ◽  
Circulatory System ◽  
Reducing Power ◽  
Antioxidant Defense System ◽  
Age Related ◽  
The Central Nervous System ◽  
High Level

Differential antioxidant action is found upon comparison of organ/tissue systems in the human body. In erythrocytes (red blood cells), which transport oxygen and carbon dioxide through the circulatory system, the most important issue is to keep hemoglobin in a functional state that requires maintaining the haem group in ferrous (Fe2+) state. Conversion of oxidized Fe3+ back into Fe2+ in hemoglobin needs a special mechanism involving a tripeptide glutathione, glucose-6-phosphate dehydrogenase, and glucose and NADPH as suppliers of reducing power. Fava beans are probably a good resource to make the detox innate system more robust as the pro-oxidant molecules in this food likely induce the upregulation of members of such mechanisms. The central nervous system consumes more oxygen than the majority of human tissues, i.e., 20% of the body’s total oxygen consumption and, therefore, it is exposed to a high level of oxidative stress. This fact, together with the progressive age-related decline in the efficiency of the antioxidant defense system, leads to neuronal death and disease. The innate mechanism operating in the central nervous system is not well known and seems different to that of the erythrocytes. The strategies of antioxidant intervention in brain will be reviewed here.

Age-related Degradation in the Central Nervous System: Assessment with Diffusion-Tensor Imaging and Quantitative Fiber Tracking

Radiology ◽  
2008 ◽  
Vol 247 (1) ◽  
pp. 179-188 ◽  
Author(s):  
Andreas Stadlbauer ◽  
Erich Salomonowitz ◽  
Guido Strunk ◽  
Thilo Hammen ◽  
Oliver Ganslandt
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Fiber Tracking ◽  
Age Related ◽  
The Central Nervous System ◽  
System Assessment
Sign in / Sign up

Export Citation Format

Share Document