Age-Related Changes of the Pattern of Non-Histone Chromatin Proteins from Rat and Mouse Liver Chromatin

Gerontology ◽  
1979 ◽  
Vol 25 (4) ◽  
pp. 219-227 ◽  
Author(s):  
Zh.A. Medvedev ◽  
M.N. Medvedeva ◽  
L. Robson
Keyword(s):  
Mouse Liver ◽  
Age Related ◽  
Liver Chromatin ◽  
Chromatin Proteins ◽  
Age Related Changes

Age-Related Changes of Supranucleosomal Structures and DNA-Synthesizing Properties of Rat Liver Chromatin

Gerontology ◽  
1991 ◽  
Vol 37 (4) ◽  
pp. 181-186 ◽  
Author(s):  
T.G. Mozzhukhina ◽  
V.N. Chabanny ◽  
E.L. Levitsky ◽  
A.Ya. Litoshenko
Keyword(s):  
Rat Liver ◽  
Age Related ◽  
Liver Chromatin ◽  
Age Related Changes

Quantitative subproteomic analysis of age-related changes in mouse liver peroxisomes by iTRAQ LC–MS/MS

2011 ◽  
Vol 879 (30) ◽  
pp. 3393-3400 ◽  
Author(s):  
Hanna Amelina ◽  
Marcus O.D. Sjödin ◽  
Jonas Bergquist ◽  
Susana Cristobal
Keyword(s):  
Mouse Liver ◽  
Age Related ◽  
Liver Peroxisomes ◽  
Age Related Changes

scholarly journals Age-Related Changes of Claudin Expression in Mouse Liver, Kidney, and Pancreas

2009 ◽  
Vol 64A (11) ◽  
pp. 1146-1153 ◽  
Author(s):  
T. D'Souza ◽  
C. A. Sherman-Baust ◽  
S. Poosala ◽  
J. M. Mullin ◽  
P. J. Morin
Keyword(s):  
Mouse Liver ◽  
Age Related ◽  
Age Related Changes

scholarly journals Internal normalization of nascent RNA sequencing experiments to identify age-related changes of the mouse liver transcriptome

2017 ◽  
Vol 3 (2) ◽  
pp. 34
Author(s):  
Sara S Fonseca Costa ◽  
Jürgen A Ripperger
Keyword(s):  
Rna Sequencing ◽  
Mouse Liver ◽  
Model System ◽  
Parallel Sequencing ◽  
Age Related ◽  
Liver Transcriptome ◽  
Transcriptional Changes ◽  
Nascent Rna ◽  
Old Mice ◽  
Age Related Changes

We are interested to detect age-related transcriptional changes in the mouse liver as model system. However, such transcriptional changes are difficult to detect against the transcriptional noise increasing with age. Here, we investigated a relative strategy to improve the sensitivity of RNA-sequencing experiments. An equal amount of nuclei from rat and mouse liver was mixed, and subsequently nascent RNA (nasRNA) extracted. For normalization purposes, the rat sample was the same, while we used triplicate samples from 3- and 15-month-old mice. The reads obtained by Illumina massive-parallel sequencing were separated, and for each gene was calculated the ratio of mouse nasRNA to rat nasRNA. As such, we could identify age-related changes of the liver transcriptome that we were not able to detect previously.

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