scholarly journals Species Differences in the Relative Densities of D1- and D2-Like Dopamine Receptor Subtypes in the Japanese Quail and Rats: An in vitro Quantitative Receptor Autoradiography Study

2009 ◽  
Vol 73 (2) ◽  
pp. 81-90 ◽  
Author(s):  
Hayley K. Kleitz ◽  
Charlotte A. Cornil ◽  
Jacques Balthazart ◽  
Gregory F. Ball
Keyword(s):  
Dopamine Receptor ◽  
Japanese Quail ◽  
Species Differences ◽  
Receptor Autoradiography ◽  
Receptor Subtypes ◽  
Quantitative Receptor Autoradiography ◽  
Dopamine Receptor Subtypes

scholarly journals Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting

FEBS Letters ◽  
2003 ◽  
Vol 556 (1-3) ◽  
pp. 276-280 ◽  
Author(s):  
Arne Heydorn ◽  
Birgitte P Søndergaard ◽  
Niels Hadrup ◽  
Birgitte Holst ◽  
Carol Renfrew Haft ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
Adaptor Proteins ◽  
Interaction Pattern ◽  
Receptor Subtypes ◽  
Receptor Targeting ◽  
Dopamine Receptor Subtypes ◽  
In Vitro Interaction

scholarly journals Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists

2021 ◽  
Author(s):  
Kirsten Tolentino ◽  
Viktoriya Mashinson ◽  
Anish Vadukoot ◽  
Corey Hopkins
Keyword(s):  
Parkinson’S Disease ◽  
Basal Ganglia ◽  
Dopamine Receptor ◽  
Receptor Subtypes ◽  
Receptor Antagonists ◽  
Dopamine Receptor Subtypes ◽  
The Brain

Abstract: The dopamine receptor 4 (D4R) is highly expressed in both motor, associative and limbic subdivisions of the coritico-basal ganglia network. Due to the distribution in the brain, there is mounting evidence pointing to a role for the D4R in the modulation of this network and its subsequent involvement in L-DOPA induced dyskinesias in Parkinson’s disease. As part of our continued effort in the discovery of novel D4R antagonists, we report the discovery and characterization of a new 3- or 4-benzyloxypiperidine scaffold as D4R antagonists. We report several D4R selective compounds (>30-fold vs. other dopamine receptor subtypes) with improved in vitro and in vivo stability over previously reported D4R antagonists.

Dopamine Receptor Subtypes and Orofacial Movement Topographies: Studies with Mutant Models

2010 ◽  
Vol 52 (4) ◽  
pp. 336-343
Author(s):  
Noriaki Koshikawa ◽  
Katsunori Tomiyama ◽  
John L. Waddington
Keyword(s):  
Dopamine Receptor ◽  
Receptor Subtypes ◽  
Dopamine Receptor Subtypes ◽  
Orofacial Movement

Effect of aging on striatal dopamine receptor subtypes in Wistar rats

1986 ◽  
Vol 7 (5) ◽  
pp. 357-361 ◽  
Author(s):  
Jacquelyn M. Henry ◽  
Charles R. Filburn ◽  
James A. Joseph ◽  
George S. Roth
Keyword(s):  
Dopamine Receptor ◽  
Wistar Rats ◽  
Striatal Dopamine ◽  
Receptor Subtypes ◽  
Dopamine Receptor Subtypes ◽  
Striatal Dopamine Receptor
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