A Further Example of Thalassemia-Hemoglobin E Disease in Turkey

1965 ◽  
Vol 34 (6) ◽  
pp. 354-360 ◽  
Author(s):  
A. Okçuoğlu ◽  
Virginia Minnich ◽  
A. Arcasoy
Keyword(s):  
Hemoglobin E ◽  
Hemoglobin E Disease

scholarly journals Hemoglobin E disease and glycosylated hemoglobin

2015 ◽  
Vol 19 (5) ◽  
pp. 683 ◽  
Author(s):  
MohammadShafi Kuchay ◽  
Ambrish Mithal ◽  
Niharika Yedla
Keyword(s):  
Glycosylated Hemoglobin ◽  
Hemoglobin E ◽  
Hemoglobin E Disease

scholarly journals Acute Effects of Blood Transfusion on Insulin Sensitivity and Pancreatic β-Cell Function in Children with β-Thalassemia/Hemoglobin E Disease

2018 ◽  
Vol 10 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Somboon Wankanit ◽  
Ampaiwan Chuansumrit ◽  
Preamrudee Poomthavorn ◽  
Patcharin Khlairit ◽  
Sarunyu Pongratanakul ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Blood Transfusion ◽  
Cell Function ◽  
Pancreatic Β Cell ◽  
Acute Effects ◽  
Β Cell ◽  
Hemoglobin E ◽  
Β Cell Function ◽  
Hemoglobin E Disease

scholarly journals The Hemoglobin E Syndromes. II. Sickle-Cell—Hemoglobin E Disease

Blood ◽  
1960 ◽  
Vol 15 (5) ◽  
pp. 610-613 ◽  
Author(s):  
MUZAFFER AKSOY
Keyword(s):  
Sickle Cell ◽  
Genetic Data ◽  
Genetic Studies ◽  
Hemoglobin E ◽  
New Family ◽  
Clinical Changes ◽  
Hemoglobin E Disease

Abstract 1. A clinical and hematologic description is presented of a patient with sickle-cell-hemoglobin E disease in a new family. In contrast to the mild hematologic and clinical changes observed in the patients described by the author previously, the clinical and hematologic manifestations in the new patient were moderate in degree. The anemia was normocytic in type. Variation in the clinical and hematologic picture of sickle cell-hemoglobin E disease has been noted. 2. Genetic studies of two families with sickle-cell-hemoglobin E disease have been presented. According to the genetic data obtained by evaluation of the genealogies of these two families, it is strongly suggested that the genes responsible for hemoglobins S, E and A are allelomorphs or linked.

Pregnancy Outcomes Among Women with Homozygous Hemoglobin E Disease: A Retrospective Cohort Study

2016 ◽  
Vol 20 (11) ◽  
pp. 2367-2371
Author(s):  
Supatra Sirichotiyakul ◽  
Phudit Jatavan ◽  
Kuntharee Traisrisilp ◽  
Theera Tongsong
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Pregnancy Outcomes ◽  
Retrospective Cohort ◽  
Hemoglobin E ◽  
Hemoglobin E Disease ◽  
Homozygous Hemoglobin E

scholarly journals DISCREPANCY BETWEEN HAEMOGLOBIN, RDW, AND MEAN CORPUSCULAR VALUES IN PATIENTS WITH BETA THALASSEMIA / HEMOGLOBIN E DISEASE AND BETA THALASSEMIA TRAIT

2019 ◽  
Vol 25 (3) ◽  
pp. 343
Author(s):  
Vinisia Setiadji ◽  
Bidasari Lubis ◽  
Adi Koesoema Aman ◽  
Herman Hariman
Keyword(s):  
Beta Thalassemia ◽  
Hemoglobin E ◽  
Thalassemia Trait ◽  
Hemoglobin E Disease

Thalassemia beta / hemoglobin E adalah suatu kondisi dengan heterozigot ganda gen pembawa thalassemia beta dan hemoglobin E. Hal ini menyebabkan kondisi dengan gambaran fenotip yang berat dibandingkan trait thalassemia beta dan trait hemoglobin E. Secara logika, nilai mean corpuscular dari thalassemia beta / hemoglobin E seharusnya memburuk. Pada penelitian ini, kami meneliti sebelas kasus dari dua keluarga dengan anggota menderita thalassemia beta / hemoglobin E.Pada keluarga-1 dua anggota dengan trait thalassemia beta memiliki nilai MCV 68 fL dan 65 fL, dan nilai MCH 21 pg dan 20 pg. Pada keluarga-2 anggota dengan trait thalassemia beta memiliki nilai MCV 60,2 fL dan MCH 18,8 pg. Anak perempuan dari kedua keluarga dengan thalassemia beta / hemoglobin E memiliki nilai mean ± SD MCV 70,8 ± 4,9 fL dan MCH 22.8 ± 2.3 pg, nilai ini signifikan lebih tinggi daripada trait thalassemia beta (p<0.05). Terdapat perbedaan yang signifikan antara nilai hemoglobin dan RDW antara thalassemia beta / hemoglobin E (p=0.001).Kami juga menemukan bahwa nilai MC dari keadaan post-transfusi signifikan lebih tinggi daripada pre-transfusi (p<0.001)Kami menyimpulkan bahwa nilai MC dari thalassemia beta / hemoglobin E secara persisten lebih tinggi daripada trait thalassemia beta. Peran transfusi darah pada pasien dengan thalassemia beta / hemoglobin E tampak memainkan peran dalam diskrepansi pada kasus ini.

scholarly journals The Hemoglobin E Syndromes. I. Hemoglobin E in Eti-Turks

Blood ◽  
1960 ◽  
Vol 15 (5) ◽  
pp. 606-609 ◽  
Author(s):  
MUZAFFER AKSOY ◽  
Kamil Tanrikulu
Keyword(s):  
Sickle Cell ◽  
Electrophoretic Study ◽  
Hemoglobin E ◽  
Hemoglobin E Disease

Abstract During an electrophoretic study of the hemoglobin from 150 persons belonging to the Eti-Turk community, two individuals with hemoglobin E trait and one case of sickle-cell-hemoglobin E disease were discovered. The results of this investigation combined with those of other electrophoretic studies performed previously in this community indicate that the incidence of hemoglobin E among Eti-Turks is 1.37 per cent. The importance of the occurrence of hemoglobin E in this community has been discussed, and a possible relationship between Eti-Turks and some people of India has been postulated.

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