Temporal Trends in Incidence and Severity of Acute Pancreatitis in Lüneburg County, Germany: A Population-Based Study

Pancreatology ◽  
2009 ◽  
Vol 9 (4) ◽  
pp. 420-426 ◽  
Author(s):  
Paul Georg Lankisch ◽  
Mirwais Karimi ◽  
Anja Bruns ◽  
Patrick Maisonneuve ◽  
Albert B. Lowenfels
Keyword(s):  
Acute Pancreatitis ◽  
Temporal Trends ◽  
Population Based ◽  
Population Based Study

scholarly journals Temporal trends in neonatal mortality and morbidity following spontaneous and clinician-initiated preterm birth in Washington State, USA: a population-based study

BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e023004 ◽  
Author(s):  
Lindsay L Richter ◽  
Joseph Ting ◽  
Giulia M Muraca ◽  
Anne Synnes ◽  
Kenneth I Lim ◽  
...  
Keyword(s):  
Neonatal Mortality ◽  
Preterm Infants ◽  
Temporal Trends ◽  
Population Based ◽  
Washington State ◽  
Late Preterm ◽  
Population Based Study ◽  
Mortality And Morbidity ◽  
Late Preterm Infants ◽  
Spontaneous Labour

ObjectiveAfter a decade of increase, the preterm birth (PTB) rate has declined in the USA since 2006, with the largest decline at late preterm (34–36 weeks). We described concomitant changes in gestational age-specific rates of neonatal mortality and morbidity following spontaneous and clinician-initiated PTB among singleton infants.Design, setting and participantsThis retrospective population-based study included 754 763 singleton births in Washington State, USA, 2004–2013, using data from birth certificates and hospitalisation records. PTB subtypes included preterm premature rupture of membranes (PPROM), spontaneous onset of labour and clinician-initiated delivery.Outcome measuresThe primary outcomes were neonatal mortality and a composite outcome including death or severe neonatal morbidity. Temporal trends in the outcomes and individual morbidities were assessed by PTB subtype. Logistic regression yielded adjusted odds ratios (AOR) per 1 year change in outcome and 95% CI.ResultsThe rate of PTB following PPROM and spontaneous labour declined, while clinician-initiated PTB increased (all p<0.01). Overall neonatal mortality remained unchanged (1.3%; AOR 0.99, CI 0.95 to 1.02), though gestational age-specific mortality following clinician-initiated PTB declined at 32–33 weeks (AOR 0.85, CI 0.74 to 0.97) and increased at 34–36 weeks (AOR 1.10, CI 1.01 to 1.20). The overall rate of the composite outcome increased (from 7.9% to 11.9%; AOR 1.06, CI 1.05 to 1.08). Among late preterm infants, combined mortality or severe morbidity increased following PPROM (AOR 1.13, CI 1.08 to 1.18), spontaneous labour (AOR 1.09, CI 1.06 to 1.13) and clinician-initiated delivery (AOR 1.10, CI 1.07 to 1.13). Neonatal sepsis rates increased among all preterm infants (AOR 1.09, CI 1.08 to 1.11).ConclusionsTiming of obstetric interventions is associated with infant health outcomes at preterm. The temporal decline in late PTB among singleton infants was associated with increased mortality among late preterm infants born following clinician-initiated delivery and increased combined mortality or severe morbidity among all late preterm infants, mainly due to increased rate of sepsis.

scholarly journals Temporal Trends of Hypovitaminosis D: A Population-Based Study of Cases Under 19 Years of Age

2020 ◽  
Vol 145 (2) ◽  
pp. AB63
Author(s):  
Alyssa Kerber ◽  
Anna Kellund ◽  
Amy Weaver ◽  
Rachel Carlson ◽  
Seema Kumar ◽  
...  
Keyword(s):  
Temporal Trends ◽  
Hypovitaminosis D ◽  
Population Based ◽  
Population Based Study

Temporal trends of pancreatic ductal adenocarcinoma in young adults in the United States: A Population-Based Study

2020 ◽  
Vol 44 (2) ◽  
pp. 204-210
Author(s):  
Mohamed M. Gad ◽  
Anas M. Saad ◽  
Muneer J. Al-Husseini ◽  
Youssef M. Abdel-Gawad ◽  
Obai M. Alsalhani ◽  
...  
Keyword(s):  
United States ◽  
Young Adults ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Temporal Trends ◽  
The United States ◽  
Population Based ◽  
Ductal Adenocarcinoma ◽  
Population Based Study

scholarly journals A Drug-Induced Acute Pancreatitis Retrospective Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Ann-Lorie Gagnon ◽  
Alexandre Lavoie ◽  
Marie-Pier Frigon ◽  
Alban Michaud-Herbst ◽  
Karine Tremblay
Keyword(s):  
Acute Pancreatitis ◽  
Chart Review ◽  
Population Based ◽  
Drug Induced ◽  
Population Based Study ◽  
Medical Chart Review ◽  
Drug Classes ◽  
Causative Drug ◽  
Conclusive Data ◽  
Positive Rechallenge

Background and Aims. Drugs are considered a relatively rare and understudied cause of acute pancreatitis (AP). The lack of convincing and conclusive data on drug-induced AP (DIAP) complicates the diagnosis as well as the identification of the causative drug. The aim of this study is to document causes of DIAP cases that occurred in the Saguenay-Lac-Saint-Jean (SLSJ) population. Methods. We have conducted a retrospective and descriptive population-based study of DIAP cases that occurred between 2006 and 2014 in the six hospitals serving the entire SLSJ population. Cases were selected from the Quebec Ministry of Health hospitalizations registry (MED-ECHO) administrative public database. A medical chart review was performed in an attempt to characterize DIAP hospitalizations and to identify the imputable drugs. Results. During the studied period, 75 cases (30.7% male, 69.3% female) were included totaling 90 hospitalizations for DIAP. Among them, 50 causative drugs were identified and were distributed in 17 different drug classes. Recurrent DIAPs were documented in 13 cases, and among them, 6 cases have experimented a positive rechallenge. Six drugs (5-fluorouracil, atorvastatin, bortezomib, nilotinib, rosuvastatin, and triamcinolone) were associated with the highest degree of evidence. The most common causative drugs of DIAP hospitalization were azathioprine (n = 7), followed by atorvastatin (n = 6), hydrochlorothiazide (n = 5), rosuvastatin (n = 4), and codeine (n = 4). Conclusions. This study has added new evidences about potentially pancreatitis-associated drugs in literature. This is the first study to report definite 5-fluorouracil- and triamcinolone-induced AP. An updated version of the evidence-based literature review is needed to support the clinicians in the identification of the causative drugs.

Trends in vertebral augmentation for spinal fractures in myeloma patients: a 2002–2012 population-based study using a large national cancer registry

2017 ◽  
Vol 10 (2) ◽  
pp. 183-190 ◽  
Author(s):  
Falgun H Chokshi ◽  
David H Howard ◽  
Jeffrey G Jarvik ◽  
Richard Duszak
Keyword(s):  
Temporal Trends ◽  
Spinal Fractures ◽  
Sociodemographic Factors ◽  
Spinal Fracture ◽  
Population Based ◽  
Vertebral Augmentation ◽  
Population Based Study ◽  
Black Patients ◽  
The Impact ◽  
Osteoporotic Spinal Fractures

PurposeTo evaluate temporal trends and factors associated with vertebral augmentation use in myeloma patients with spinal fractures from 2002 to 2012.MethodsThis retrospective cohort study used the Surveillance, Epidemiology and End Results (SEER)-Medicare claims database for 2002 through 2012. We included patients age ≥66 years with myeloma and spinal fractures. First, we evaluated receipt of vertebral augmentation. Second, multivariate logistic regression was used to assess the impact of sociodemographic factors, treatment facility type, and underlying comorbidities on the odds of undergoing vertebral augmentation.ResultsOf 4725 myeloma patients with spinal fractures, 653 underwent vertebral augmentation. Procedures increased initially from <1.7% in 2002 to 21.0% (109/520) in 2007, 18.6% (81/435) in 2008, 21.4% (109/509) in 2009, and 17.5% (76/435) in 2011. Patients with a spinal fracture before myeloma diagnosis were twice as likely to undergo vertebral augmentation as patients with fracture after myeloma diagnosis (OR 2.06, 95% CI 1.55 to 2.75). Black patients were half as likely to undergo vertebral augmentation as white patients (OR 0.48, 95% CI 0.34 to 0.68). Patients with 3–5 comorbidities (OR 0.78, 95% CI 0.64 to 0.96) and ≥6 comorbidities (OR 0.69, 95% CI 0.54 to 0.87) were less likely than patients with 0–2 comorbidities to undergo vertebral augmentation.ConclusionsVertebral augmentation for myeloma patients with spinal fractures peaked between 2007 and 2009 and then declined. Providers may have adopted vertebral augmentation in myeloma patients since its introduction, and potentially modified practice patterns following the publication of trials of vertebral augmentation in patients with osteoporotic spinal fractures.

scholarly journals Temporal trends in the birth rates and perinatal mortality of twins: A population-based study in China

PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0209962 ◽  
Author(s):  
Changfei Deng ◽  
Li Dai ◽  
Ling Yi ◽  
Xiaohong Li ◽  
Kui Deng ◽  
...  
Keyword(s):  
Perinatal Mortality ◽  
Temporal Trends ◽  
Population Based ◽  
Birth Rates ◽  
Population Based Study
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