Red Blood Cell Membrane and Serum Sialic Acid in Relation to Erythrocyte Sedimentation Rate

1980 ◽  
Vol 64 (5) ◽  
pp. 276-280 ◽  
Author(s):  
H. Levinsky ◽  
G. Rothman ◽  
M. Lapidot ◽  
D. Allalouf
Keyword(s):  
Sialic Acid ◽  
Cell Membrane ◽  
Blood Cell ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Red Blood Cell ◽  
Red Blood Cell Membrane ◽  
Erythrocyte Sedimentation ◽  
Serum Sialic Acid

The red blood cell count and the erythrocyte sedimentation rate in the diagnosis of polycythaemia vera

2019 ◽  
Vol 104 (1) ◽  
pp. 46-54
Author(s):  
Vardan Nersesjan ◽  
Kristoffer A. Zervides ◽  
Anders L. Sørensen ◽  
Lasse Kjær ◽  
Vibe Skov ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Red Blood Cell ◽  
Polycythaemia Vera ◽  
Blood Cell Count ◽  
Erythrocyte Sedimentation ◽  
Red Blood Cell Count

Microfluidic-based measurement of RBC aggregation and the ESR using a driving syringe system

2018 ◽  
Vol 10 (16) ◽  
pp. 1805-1816 ◽  
Author(s):  
Yang Jun Kang
Keyword(s):  
Blood Cell ◽  
Erythrocyte Sedimentation Rate ◽  
Microfluidic Device ◽  
Sedimentation Rate ◽  
Red Blood Cell ◽  
Aggregation Index ◽  
Erythrocyte Sedimentation ◽  
System P ◽  
Rbc Aggregation

The erythrocyte sedimentation rate (ESR) and red blood cell (RBC) aggregation in a driving syringe are simultaneously measured by quantifying blood press index (Ipress) and RBC aggregation index (IRA) in a microfluidic device.

scholarly journals Red Blood Cell Membrane-Camouflaged Tedizolid Phosphate-Loaded PLGA Nanoparticles for Bacterial-Infection Therapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 99
Author(s):  
Xinyi Wu ◽  
Yichen Li ◽  
Faisal Raza ◽  
Xuerui Wang ◽  
Shulei Zhang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Cell Membrane ◽  
Blood Cell ◽  
Sustained Release ◽  
Delivery System ◽  
Red Blood Cell ◽  
Multiple Drug Resistance ◽  
Plga Nanoparticles ◽  
Multiple Drug ◽  
Red Blood Cell Membrane

Multiple drug resistance (MDR) in bacterial infections is developed with the abuse of antibiotics, posing a severe threat to global health. Tedizolid phosphate (TR-701) is an efficient prodrug of tedizolid (TR-700) against gram-positive bacteria, including methicillin-sensitive staphylococcus aureus (MSSA) and methicillin-resistant staphylococcus aureus (MRSA). Herein, a novel drug delivery system: Red blood cell membrane (RBCM) coated TR-701-loaded polylactic acid-glycolic acid copolymer (PLGA) nanoparticles (RBCM-PLGA-TR-701NPs, RPTR-701Ns) was proposed. The RPTR-701Ns possessed a double-layer core-shell structure with 192.50 ± 5.85 nm in size, an average encapsulation efficiency of 36.63% and a 48 h-sustained release in vitro. Superior bio-compatibility was confirmed with red blood cells (RBCs) and HEK 293 cells. Due to the RBCM coating, RPTR-701Ns on one hand significantly reduced phagocytosis by RAW 264.7 cells as compared to PTR-701Ns, showing an immune escape effect. On the other hand, RPTR-701Ns had an advanced exotoxins neutralization ability, which helped reduce the damage of MRSA exotoxins to RBCs by 17.13%. Furthermore, excellent in vivo bacteria elimination and promoted wound healing were observed of RPTR-701Ns with a MRSA-infected mice model without causing toxicity. In summary, the novel delivery system provides a synergistic antibacterial treatment of both sustained release and bacterial toxins absorption, facilitating the incorporation of TR-701 into modern nanotechnology.

Sign in / Sign up

Export Citation Format

Share Document