Automated Cytochemistry in Non-Hodgkin’s Lymphoma: A New Method for Determination of Cells from Lymph Node Biopsy

1986 ◽  
Vol 75 (4) ◽  
pp. 199-202
Author(s):  
Ahnond Bunyaratvej ◽  
Pattraporn Boonkanta ◽  
Prawat Nítiyanant ◽  
Suntaree Apibal ◽  
Natth Bhamarapravati
Keyword(s):  
Lymph Node ◽  
Hodgkin’S Lymphoma ◽  
Lymph Node Biopsy ◽  
New Method ◽  
Hodgkin's Lymphoma ◽  
Node Biopsy ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma

scholarly journals Translocation (14;18)-positive cells are present in the circulation of the majority of patients with localized (stage I and II) follicular non- Hodgkin's lymphoma

Blood ◽  
1993 ◽  
Vol 82 (8) ◽  
pp. 2510-2516 ◽  
Author(s):  
AC Lambrechts ◽  
PE Hupkes ◽  
LC Dorssers ◽  
MB van't Veer
Keyword(s):  
Bone Marrow ◽  
Lymph Node ◽  
Peripheral Blood ◽  
Hodgkin’S Lymphoma ◽  
Lymph Node Biopsy ◽  
Stage I ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Sensitive Polymerase Chain Reaction

Abstract Stage I and II follicular non-Hodgkin's lymphoma (NHL) is clinically defined as a localized disease. To study the possibility that this disease is in fact disseminated, we used the sensitive polymerase chain reaction (PCR) method using translocation (14;18) as marker. Samples from 21 patients who were clinically diagnosed with stage I or II follicular NHL were analyzed for the presence of t(14;18)-positive cells using PCR. We analyzed (1) the diagnostic lymph node biopsy and (2) the peripheral blood or bone marrow samples from these patients. Translocation (14;18) cells were detected in the diagnostic lymph node biopsies of 12 patients. In 9 of these patients, t(14;18)-positive cells were detected in peripheral blood and/or bone marrow samples at diagnosis and/or after therapy. Thus, in 75% of the follicular NHL patients carrying the t(14;18) as a marker for lymphoma cells, t(14;18)- positive cells were detected in peripheral blood and bone marrow at diagnosis and after therapy. Our results show that t(14;18)-positive cells can be detected in the circulation of patients with stage I and II follicular NHL, indicating that, although diagnosed as localized, the disease is disseminated.

scholarly journals Translocation (14;18)-positive cells are present in the circulation of the majority of patients with localized (stage I and II) follicular non- Hodgkin's lymphoma

Blood ◽  
1993 ◽  
Vol 82 (8) ◽  
pp. 2510-2516
Author(s):  
AC Lambrechts ◽  
PE Hupkes ◽  
LC Dorssers ◽  
MB van't Veer
Keyword(s):  
Bone Marrow ◽  
Lymph Node ◽  
Peripheral Blood ◽  
Hodgkin’S Lymphoma ◽  
Lymph Node Biopsy ◽  
Stage I ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Sensitive Polymerase Chain Reaction

Stage I and II follicular non-Hodgkin's lymphoma (NHL) is clinically defined as a localized disease. To study the possibility that this disease is in fact disseminated, we used the sensitive polymerase chain reaction (PCR) method using translocation (14;18) as marker. Samples from 21 patients who were clinically diagnosed with stage I or II follicular NHL were analyzed for the presence of t(14;18)-positive cells using PCR. We analyzed (1) the diagnostic lymph node biopsy and (2) the peripheral blood or bone marrow samples from these patients. Translocation (14;18) cells were detected in the diagnostic lymph node biopsies of 12 patients. In 9 of these patients, t(14;18)-positive cells were detected in peripheral blood and/or bone marrow samples at diagnosis and/or after therapy. Thus, in 75% of the follicular NHL patients carrying the t(14;18) as a marker for lymphoma cells, t(14;18)- positive cells were detected in peripheral blood and bone marrow at diagnosis and after therapy. Our results show that t(14;18)-positive cells can be detected in the circulation of patients with stage I and II follicular NHL, indicating that, although diagnosed as localized, the disease is disseminated.

scholarly journals The Dangers of Immediately Performing a Sensitive and Specific Investigation versus the Dangers of Delaying It: A Cautionary Case of Hodgkin’s Lymphoma

2020 ◽  
Author(s):  
Takahiro Ito ◽  
Hiroshi Sawachika ◽  
Yukinori Harada ◽  
Taro Shimizu
Keyword(s):  
Lymph Node ◽  
Hodgkin’S Lymphoma ◽  
Gastrointestinal Endoscopy ◽  
Lymph Node Biopsy ◽  
Hodgkin's Lymphoma ◽  
Haemophagocytic Lymphohistiocytosis ◽  
Gastrointestinal Malignancies ◽  
Node Biopsy ◽  
History Of ◽  
Diagnostic Outcome

A 60-year-old man was admitted with a 1-month history of fever and weight loss. Multiple lymphadenopathies and haemophagocytic lymphohistiocytosis were noted from the beginning, suggesting lymphoma. However, lymph node biopsy was deferred because lymph node biopsy was regarded as being invasive and requires general anaesthesia, and because other possible differential diagnoses including gastrointestinal malignancies and TAFRO syndrome were being considered. Instead, investigations including gastrointestinal endoscopy and bone marrow biopsy were prioritized. The patient was eventually diagnosed with Hodgkin’s lymphoma based on lymph node biopsy but died during chemotherapy. Physicians should prioritize the tests that are most directly related to the diagnostic outcome, even if they are invasive.

Primary laryngeal lymphoma in China: a retrospective study of the last 25 years

2019 ◽  
Vol 133 (09) ◽  
pp. 792-795
Author(s):  
P Zhao ◽  
Y Zhou ◽  
J Li
Keyword(s):  
Lymph Node ◽  
T Cell ◽  
Hodgkin’S Lymphoma ◽  
Chinese Language ◽  
Lymph Node Involvement ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Node Involvement ◽  
Language Literature

AbstractObjectiveTo retrospectively study the primary laryngeal lymphoma cases in China reported in Chinese-language literature.MethodChinese-language literature was searched for papers on primary laryngeal lymphoma published in the last 25 years.ResultsThe selected papers comprised a total of 115 cases. The male-to-female ratio was 3.4:1. Non-Hodgkin's lymphoma was the exclusive pathological type. The estimated 3-year, 5-year and 10-year survival rates were 70.9 ± 6.4 per cent, 63.4 ± 7.6 per cent and 56.4 ± 9.5 per cent respectively, as determined by Kaplan–Meier analysis. B-cell non-Hodgkin's lymphoma patients had a better prognosis than T-cell non-Hodgkin's lymphoma patients (p = 0.032). Patients with lymph node involvement at diagnosis had a poorer prognosis (p < 0.01).ConclusionPrimary laryngeal lymphoma is a rare disease with no specific clinical features. More than one biopsy might be needed to obtain the correct diagnosis. Proper treatment could lead to promising outcomes. The T-cell subtype and lymph node involvement at diagnosis might indicate worse prognosis.

Primary non-Hodgkin's lymphoma arising in an intramammary lymph node

2005 ◽  
Vol 46 (3) ◽  
pp. 451-455 ◽  
Author(s):  
Ioannis Venizelos ◽  
Zoi Tatsiou ◽  
Sofia Vakalopoulou ◽  
Eudokia Mandala ◽  
Vasiliki Garipidou
Keyword(s):  
Lymph Node ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Intramammary Lymph Node

scholarly journals Primary, Bilateral and Diffuse Renal Non-Hodgkin’s Lymphoma in a Young Woman Suffering from Turner Syndrome

2021 ◽  
Vol 11 (7) ◽  
pp. 644
Author(s):  
Bernardo Rossini ◽  
Tetiana Skrypets ◽  
Carla Minoia ◽  
Angela Maria Quinto ◽  
Gian Maria Zaccaria ◽  
...  
Keyword(s):  
Lymph Node ◽  
Rare Disease ◽  
Turner Syndrome ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Rare Form ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Extranodal Lymphomas ◽  
Personalized Approach

Primary renal lymphoma (PRL) is a rare form of non-Hodgkin’s lymphoma (NHL) restricted to and primarily involving one or both kidneys, with no lymph node extension. It accounts for <1% of extranodal lymphomas, and descriptions in the literature are limited. Here, we describe an unprecedented case of bilateral PRL in a 44-year-old woman with Turner syndrome and discuss both diagnostic and therapeutic issues in the light of the available literature in the field. A personalized approach to this rare disease is necessary.

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