Steroid-Responsive Idiopathic Cold Agglutinin Disease: A Case Report

1989 ◽  
Vol 81 (3) ◽  
pp. 166-168 ◽  
Author(s):  
M. Lahav ◽  
I. Rosenberg ◽  
A.J. Wysenbeek
Keyword(s):  
Case Report ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease

Perioperative considerations in the management of cold agglutinin disease in laparoscopic surgery

2021 ◽  
Vol 14 (5) ◽  
pp. e241294
Author(s):  
Yisi D Ji ◽  
Paul M Cavallaro ◽  
Britlyn D Orgill
Keyword(s):  
Case Report ◽  
Laparoscopic Surgery ◽  
Acute Cholecystitis ◽  
Operating Room ◽  
Patient Outcomes ◽  
Cold Agglutinin ◽  
Surgical Team ◽  
Cold Agglutinin Disease ◽  
Disease Exacerbation ◽  
Multidisciplinary Collaboration

An 80-year-old man with idiopathic cold agglutinin disease presented with acute cholecystitis. We describe operating room and anaesthetic considerations for patients with cold agglutinin disease and measures that can be taken to prevent disease exacerbation in this case report. Multidisciplinary collaboration and planning between the operative room staff, anaesthesia team and surgical team are needed to ensure safe surgery and optimal patient outcomes.

Successful treatment of relapsed and refractory cold agglutinin disease with bortezomib: case report

2019 ◽  
Vol 85 ◽  
pp. S68-S69
Author(s):  
S. Çelik ◽  
Z. Güven ◽  
B. Eser ◽  
L. Kaynar ◽  
M. Çetin ◽  
...  
Keyword(s):  
Case Report ◽  
Successful Treatment ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease

scholarly journals Intraoperative pulmonary thromboembolism in a patient with cold agglutinin disease: a case report

2020 ◽  
Vol 27 (5) ◽  
pp. 411-412
Author(s):  
Haruna Yamamoto ◽  
Satoru Kayama ◽  
Taichi Onimaru ◽  
Midori Imaizumi ◽  
Kinuko Kubota ◽  
...  
Keyword(s):  
Case Report ◽  
Pulmonary Thromboembolism ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease

Anesthetic Management for the Open Heart Surgery in a Patient with Cold Agglutinin Disease: Case report

2003 ◽  
Vol 45 (1) ◽  
pp. 157
Author(s):  
Francis Sahngun Nahm ◽  
Jong Sung Kim ◽  
Byung Moon Ham ◽  
Hyun Soo Moon ◽  
Sung Hee Han
Keyword(s):  
Case Report ◽  
Heart Surgery ◽  
Anesthetic Management ◽  
Open Heart Surgery ◽  
Cold Agglutinin ◽  
Open Heart ◽  
Cold Agglutinin Disease ◽  
Disease Case

Unusually Severe Course of Autoimmune Hemolytic Anemia / Cold Agglutinin Disease: A Case Report

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S165-S165
Author(s):  
M M Yilmaz ◽  
Y Tanhehco
Keyword(s):  
Case Report ◽  
Plasma Exchange ◽  
Hemolytic Anemia ◽  
Autoimmune Hemolytic Anemia ◽  
Middle Lobe ◽  
Cold Agglutinin ◽  
Upper Respiratory Tract ◽  
Cold Agglutinin Disease ◽  
Cell Surface Antigens ◽  
Short Period

Abstract Introduction/Objective Autoimmune hemolytic anemia (AIHA) is a group of disorders with limited epidemiological and clinical data, characterized by hemolysis due to autoantibodies against red blood cell surface antigens. Cold agglutinins account for about 25% of all AIHA, which can agglutinate erythrocytes at 0-4 °C. Cold agglutinin disease (CAD) is a self limited disease and usually does not cause significant hemolysis. Here, we report a case with an unusually severe course for secondary CAD and role of plasma exchange in the management. Methods A 53-year-old male patient with no known past medical history presented to the emergency department with shortness of breath and syncope after a week of upper respiratory tract infection symptoms. The patient became profoundly anemic (presented with 8.1 g/dL hemoglobin level and progressively decline to 4.2 g/dL) in a short period of time. Upon initial evaluation, his peripheral blood smear demonstrated clumps of RBCs. Direct anti-globulin testing was negative for IgG but positive for C3 which is consistent with CAD. A respiratory PCR panel detected Rhinovirus. Mycoplasma and EBV IgM were negative. Additionally, chest X-ray showed right middle lobe pneumonia that was treated with antibiotics. Patient received multiple transfusions of pre-warmed pRBCS and showed initial improvement but eventually went into respiratory failure and cardiac arrest with return of spontaneous circulation after 8 minutes of CPR. Subsequently, plasma exchange was started. Only after intiation of plasma exchange, the patient’s ongoing hemolysis was stabilized. Conclusion This case report presents a patient with unexpectedly rapid and severe hemolysis from secondary cold agglutinin disease. Interestingly, the case appeared not to be caused by EBV or Mycoplasma pneumonia infection but Rhinovirus. Further studies confirmed patient had no autoimmune disorder or lymphoid malignancy that may had initiated secondary CAD. On the management aspect, pre-warmed RBC transfusions were not sufficient to stabilize the patient’s condition. Plasma exchange was able to control ongoing hemolysis within 2 sessions successfully.

scholarly journals A novel method for demonstrating cold agglutinin disease: a case report

2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Thomas A. Vo ◽  
Zack Oakey ◽  
Yasir A. Khan ◽  
Donald S. Minckler
Keyword(s):  
Case Report ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease ◽  
Novel Method

PRO55 Impact of Cold Agglutinin Disease and Its Related Fatigue on Patients' Daily Life: An Online Survey Among 50 US Patients

2021 ◽  
Vol 24 ◽  
pp. S207
Author(s):  
F. Joly ◽  
L.A. Schmitt ◽  
P.A. McGee Watson ◽  
E. Pain ◽  
D. Testa
Keyword(s):  
Online Survey ◽  
Daily Life ◽  
Cold Agglutinin ◽  
Cold Agglutinin Disease
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