Time Course Study on the Action of 5-Hydroxytryptamine on Gastric Secretion and Mucosal Blood Flow and on Ethanol-lnduced Gastric Mucosal Damage in Rats

Digestion ◽  
1992 ◽  
Vol 53 (1-2) ◽  
pp. 79-87 ◽  
Author(s):  
C.H. Cho ◽  
B.S. Qiu ◽  
C.T. Luk ◽  
C.W. Ogle
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Time Course ◽  
Mucosal Blood Flow ◽  
Mucosal Damage ◽  
Gastric Mucosal Damage ◽  
Time Course Study

Effects of cimetidine upon gastric secretion and mucosal blood flow in the rat stressed by restraint

1980 ◽  
Vol 176 (3) ◽  
pp. 207-217 ◽  
Author(s):  
J. Hemmer ◽  
P. O. Schwille ◽  
W. Schellerer ◽  
W. Hofmann
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow

scholarly journals Role of capsaicin sensitive nerves in epidermal growth factor effects on gastric mucosal injury and blood flow

Gut ◽  
1998 ◽  
Vol 42 (3) ◽  
pp. 344-350 ◽  
Author(s):  
J Y Kang ◽  
C H Teng ◽  
F C Chen ◽  
A Wee
Keyword(s):  
Blood Flow ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Mucosal Injury ◽  
Gastric Mucosal Injury ◽  
Gastric Mucosal Damage ◽  
Arterial Infusion ◽  
Epidermal Growth

Background—Epidermal growth factor (EGF) and capsaicin protect against experimental gastric mucosal injury. Capsaicin exerts its gastroprotective effect by stimulating afferent neurones leading to release of calcitonin gene related peptide (CGRP) which causes gastric hyperaemia. EGF also causes gastric hyperaemia but whether it acts via capsaicin sensitive neurones is unknown.Aims—To assess the influence of: (1) capsaicin desensitisation on EGF effects on gastric mucosal injury and gastric mucosal blood flow; and (2) close arterial infusion of hCGRP8–37, a CGRP antagonist, on EGF effects on gastric mucosal blood flow.Methods—The absolute ethanol induced gastric mucosal injury model in the rat was used. Gastric mucosal damage was assessed by planimetry and light microscopy. Gastric mucosal blood flow was measured by laser Doppler flowmetry in a gastric chamber preparation.Results—Capsaicin desensitisation abolished the gastroprotective and gastric hyperaemic effects of EGF. Close arterial infusion of hCGRP8–37 antagonised the hyperaemic effect of both capsaicin and EGF.Conclusion—Results show that EGF may exert its gastroprotective and gastric hyperaemic effects via capsaicin sensitive afferent neurones.

Methionine-Enkephalin Stimulates Gastric Secretion and Gastric Mucosal Blood Flow

1978 ◽  
Vol 158 (2) ◽  
pp. 156-160 ◽  
Author(s):  
S. J. Konturek ◽  
W. Pawlik ◽  
K. M. Walus ◽  
D. H. Coy ◽  
A. V. Schally
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Methionine Enkephalin

Basal Gastric Secretion, Mucosal Blood Flow and Associated Fasting Blood Hormones in the Rat

1982 ◽  
Vol 14 (5) ◽  
pp. 358-367 ◽  
Author(s):  
E. Hanisch ◽  
P.O. Schwille ◽  
W. Engelhardt
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow ◽  
Blood Hormones
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