Effectiveness of Nedocromil Sodium versus Placebo as Additions to Routine Asthma Maintenance Therapy: a Multicentre, Double-Blind, Group Comparative Trial

Respiration ◽  
1989 ◽  
Vol 56 (3-4) ◽  
pp. 204-211 ◽  
Author(s):  
S. Bianco ◽  
N. Del Bono ◽  
V. Grassi ◽  
U. Orefice
Keyword(s):  
Maintenance Therapy ◽  
Comparative Trial ◽  
Nedocromil Sodium ◽  
Double Blind

Group Comparative Trial of 2% Nedocromil Sodium with Placebo in the Treatment of Seasonal Allergic Conjunctivitis

1994 ◽  
Vol 4 (1) ◽  
pp. 19-23 ◽  
Author(s):  
A. Stockwell ◽  
D.L. Easty
Keyword(s):  
Allergic Conjunctivitis ◽  
Comparative Trial ◽  
Nedocromil Sodium ◽  
Pollen Count ◽  
Double Blind ◽  
High Pollen ◽  
Seasonal Allergic Conjunctivitis ◽  
Significant Difference

A double blind group comparative trial comparing 2% nedocromil sodium with placebo in treating seasonal allergic conjunctivitis over a four week period is reported. Sixty-four patients were analysed. During the period of peak pollen challenge, statistically significant differences in favour of nedocromil sodium for itching and soreness were demonstrated. During a longer period of a less high pollen count, a significant difference in favour of nedocromil sodium was shown only for the symptom of soreness.

A Double-Blind Group Comparative Trial of Nedocromil Sodium and Placebo in the Management of Bronchial Asthma

1988 ◽  
Vol 16 (3) ◽  
pp. 216-224 ◽  
Author(s):  
A. J. Fairfax ◽  
M. Allbeson
Keyword(s):  
Concomitant Medication ◽  
Adverse Reactions ◽  
Comparative Trial ◽  
Forced Expiratory Volume ◽  
Nedocromil Sodium ◽  
Night Time ◽  
Double Blind ◽  
Asthmatic Patients ◽  
Asthma Symptoms ◽  
Adult Asthmatic

A 3-month double-blind group comparative trial of nedocromil sodium (4 mg twice daily) and placebo was carried out in 30 adult asthmatic patients maintained on bronchodilator therapy. Fifteen patients received each treatment. Subjective (asthma symptoms and severity) and objective (lung function and use of concomitant medication) variables were measured to monitor the response to trial treatments. Significant differences in favour of nedocromil sodium for night-time asthma, daytime asthma, cough, daytime bronchodiiator use and clinic assessment of forced expiratory volume during the first second of expiration were observed by week 4 of the trial. The diurnal variation in peak expiratory flow rate was reduced in the nedocromil sodium treated patients. There were no serious adverse reactions and no treatment related changes in haematological findings, blood biochemistry or urinalysis.

A Multicentric Clinical Trial Comparing Otocerol® with Cerumol® as Cerumenolytics

1978 ◽  
Vol 6 (3) ◽  
pp. 241-244 ◽  
Author(s):  
Gabriel Jaffé ◽  
Jack Grimshaw
Keyword(s):  
Clinical Trial ◽  
General Practitioners ◽  
Comparative Trial ◽  
Double Blind ◽  
Better Than

Fifteen general practitioners conducted a randomized, double-blind comparative trial of two cerumenolytics, namely, Otocerol® and Cerumol®. A total of 106 patients were entered into the study (fifty-three in each group). Otocerol was shown to be marginally better than Cerumol in all parameters evaluated.

Treatment of Reticular and Telangiectatic Leg Veins: Double-Blind, Prospective Comparative Trial of Polidocanol and Hypertonic Saline

2012 ◽  
Vol 38 (8) ◽  
pp. 1322-1330 ◽  
Author(s):  
Jennifer D. Peterson ◽  
Mitchel P. Goldman ◽  
Robert A. Weiss ◽  
David M. Duffy ◽  
Sabrina G. Fabi ◽  
...  
Keyword(s):  
Hypertonic Saline ◽  
Comparative Trial ◽  
Double Blind
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