Glucagon-Like Peptide-1 and the Glucose Competence Concept of Pancreatic Beta-Cell Function

1997 ◽  
pp. 171-193 ◽  
Author(s):  
George G. Holz ◽  
Colin A. Leech
Keyword(s):  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1 ◽  
Pancreatic Beta Cell Function

Compensation in pancreatic beta-cell function in subjects with glucokinase mutations

Diabetes ◽  
1994 ◽  
Vol 43 (5) ◽  
pp. 718-723 ◽  
Author(s):  
J. Sturis ◽  
I. J. Kurland ◽  
M. M. Byrne ◽  
E. Mosekilde ◽  
P. Froguel ◽  
...  
Keyword(s):  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function ◽  
Glucokinase Mutations

Effect of troglitazone on insulin sensitivity and pancreatic beta-cell function in women at high risk for NIDDM

Diabetes ◽  
1996 ◽  
Vol 45 (11) ◽  
pp. 1572-1579 ◽  
Author(s):  
K. Berkowitz ◽  
R. Peters ◽  
S. L. Kjos ◽  
J. Goico ◽  
A. Marroquin ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
High Risk ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

scholarly journals Serum CA19-9 Level Associated with Metabolic Control and Pancreatic Beta Cell Function in Diabetic Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Haoyong Yu ◽  
Ruixia Li ◽  
Lei Zhang ◽  
Haibing Chen ◽  
Yuqian Bao ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Beta Cell ◽  
Total Cholesterol ◽  
Beta Cell Function ◽  
Cell Function ◽  
Total Cholesterol Level ◽  
Pancreatic Beta Cell ◽  
Elevated Serum ◽  
Diabetic Patients ◽  
Pancreatic Beta Cell Function

CA19-9 is a tumor-associated antigen. It is also a marker of pancreatic tissue damage that might be caused by diabetes. Long-term poor glycemic control may lead to pancreatic beta cell dysfunction which is reflected by elevated serum CA19-9 level. Intracellular cholesterol accumulation leads to islet dysfunction and impaired insulin secretion which provide a new lipotoxic model. This study firstly found total cholesterol was one of the independent contributors to CA19-9. Elevated serum CA19-9 level in diabetic patients may indicate further investigations of glycemic control, pancreatic beta cell function, and total cholesterol level.

scholarly journals Age-Related Mitochondrial DNA Depletion and the Impact on Pancreatic Beta Cell Function

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e115433 ◽  
Author(s):  
Donna L. Nile ◽  
Audrey E. Brown ◽  
Meutia A. Kumaheri ◽  
Helen R. Blair ◽  
Alison Heggie ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Beta Cell ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Age Related ◽  
Mitochondrial Dna Depletion ◽  
Pancreatic Beta Cell Function ◽  
The Impact

scholarly journals OR31-6 Insulin Sensitivity and Pancreatic Beta-Cell Function in Patients with Primary Aldosteronism

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Shivraj Grewal ◽  
Andin Fosam ◽  
Liam Chalk ◽  
Arjun Deven ◽  
Mari Suzuki ◽  
...  
Keyword(s):  
Insulin Sensitivity ◽  
Beta Cell ◽  
Primary Aldosteronism ◽  
Beta Cell Function ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Pancreatic Beta Cell Function

scholarly journals Circulating C-Peptide: Measurement and Clinical Application

1981 ◽  
Vol 18 (3) ◽  
pp. 125-130 ◽  
Author(s):  
J Peter Ashby ◽  
Brian M Frier
Keyword(s):  
Beta Cell ◽  
Beta Cell Function ◽  
Plasma Insulin ◽  
Cell Function ◽  
Pancreatic Beta Cell ◽  
Plasma Insulin Concentration ◽  
C Peptide ◽  
Clinical Disorders ◽  
Pancreatic Beta Cell Function ◽  
Secretory Capacity

Pancreatic beta-cell function is usually assessed by the measurement of plasma insulin concentration in various clinical situations. However, the advent of an assay for the measurement of connecting-peptide (C-peptide) concentration in plasma has provided a further method for the assessment of the secretory capacity of the pancreatic beta cell in clinical disorders, particularly in the investigation of hypoglycaemia. The metabolism and immunoassay methodology of C-peptide are reviewed, and its application in clinical practice is outlined.

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