Modification of Cisplatin-Induced Renal p-Aminohippurate Uptake Alteration and Lipid Peroxidation by Thiols, Ginkgo biloba Extract, Deferoxamine and Torbafylline

Nephron ◽  
1995 ◽  
Vol 70 (4) ◽  
pp. 425-429 ◽  
Author(s):  
G. Inselmann ◽  
A. Blöhmer ◽  
W. Kottny ◽  
U. Nellessen ◽  
H. Hänel ◽  
...  
1997 ◽  
Vol 20 (3) ◽  
pp. 141-144 ◽  
Author(s):  
M. Deveci ◽  
I. Dibirdik ◽  
B. Çeliköz ◽  
N. Selmanpakoĝlu ◽  
U. Kisa

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Claudio Bucolo ◽  
Giuseppina Marrazzo ◽  
Chiara Bianca Maria Platania ◽  
Filippo Drago ◽  
Gian Marco Leggio ◽  
...  

Diabetic retinopathy is a complex condition where inflammation and oxidative stress represent crucial pathways in the pathogenesis of the disease. Aim of the study was to investigate the effects of a fortified extract of red berries,Ginkgo bilobaand white willow bark containing carnosine andα-lipoic acid in early retinal and plasma changes of streptozotocin-induced diabetic rats. Diabetes was induced by a single streptozotocin injection in Sprague Dawley rats. Diabetics and nondiabetic (control) rats were treated daily with the fortified extract for the ten days. Retina samples were collected and analyzed for their TNF-αand VEGF content. Moreover, plasma oxidative stress was evaluated by thiobarbituric acid reacting substances (TBARS). Increased TNF-αand VEGF levels were observed in the retina of diabetic rats. Treatment with the fortified extract significantly lowered retinal cytokine levels and suppressed diabetes-related lipid peroxidation. These data demonstrate that the fortified extract attenuates the degree of retinal inflammation and plasma lipid peroxidation preserving the retina in early diabetic rats.


2007 ◽  
Vol 21 (8) ◽  
pp. 735-740 ◽  
Author(s):  
Alejandro D. Boveris ◽  
Monica Galleano ◽  
Susana Puntarulo

1998 ◽  
Vol 28 (1) ◽  
pp. 69-71 ◽  
Author(s):  
Ö. Çolak ◽  
A. Şahin ◽  
Ö. Alatas ◽  
M. Inal ◽  
B. Yaşar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document