Modulation of Proteinuria and Renal Xanthine Oxidase Activity by Dietary Proteins in Acute Adriamycin Nephrosis in Rats: Lack of Correlation with Intra- and Extracellular Amino Acids

Nephron ◽  
1992 ◽  
Vol 60 (3) ◽  
pp. 342-348 ◽  
Author(s):  
Alberto Canepa ◽  
Gian Marco Ghiggeri ◽  
Alba Carrea ◽  
Fabrizio Ginevri ◽  
Antonella Trivelli ◽  
...  
Keyword(s):  
Amino Acids ◽  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Dietary Proteins ◽  
Xanthine Oxidase Activity

Assay of Biologic Value of Milk Proteins by Liver Xanthine Oxidase Determination

PEDIATRICS ◽  
1958 ◽  
Vol 21 (4) ◽  
pp. 554-554
Keyword(s):  
Xanthine Oxidase ◽  
Infant Feeding ◽  
Oxidase Activity ◽  
Nutritional Value ◽  
Human Subjects ◽  
Milk Proteins ◽  
Dietary Proteins ◽  
Human Infants ◽  
Xanthine Oxidase Activity ◽  
Wide Range

The evaluation of the biologic value of proteins in products designed for infant feeding by the use of human subjects presents almost insuperable difficulties, such as the obtainment of sufficient numbers of suitable subjects, expense, provision of suitable controls in the experiments, and the technical difficulties in the few indices which can be applied for evaluation. In spite of the uncertainty concerning the validity of extrapolation of results obtained in animals to human nutrition, it has been the objective of many investigators to find a convenient and suitable means of estimating the biologic value of proteins in foods prepared for infant consumption. This is particularly desirable because of the possibility of changes in nutritional value resulting from methods of processing of foods for infants. The authors report their results with an indirect approach to studying the biologic value of proteins through the activity of xanthine oxidase in the liver of young adult and growing rats. Previous studies had indicated a good correlation between the activity of this liver enzyme and the biologic value of proteins. While controlling other factors which influence the activity of xanthine oxidase in the liver, rats were fed test feedings of prepared milk products and a soya bean product designed for infant feeding. The protein in these products was compared with protein from other sources having a wide range of biologic value. The xanthine oxidase activity in the livers of the experimental animal was found to correlate closely with the biologic values obtained by other methods for the protein in the test diets. It was concluded that liver xanthine oxidase activity reflects the biologic value of dietary proteins and that the method employed for its measurement permits the study of the biologic value of protein in diets which normally produce diarrhea in the rats. Such information should be useful in the case of new products before subjecting human infants to clinical trial.

Stabilization of Xanthine Oxidase Activity by Salicylate

Nature ◽  
1956 ◽  
Vol 178 (4524) ◽  
pp. 88-89 ◽  
Author(s):  
F. BERGEL ◽  
R. C. BRAY
Keyword(s):  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Xanthine Oxidase Activity

Effect of acetyl-l-carnitine on lipid peroxidation and xanthine oxidase activity in rat skeletal muscle

1993 ◽  
Vol 18 (11) ◽  
pp. 1157-1162 ◽  
Author(s):  
C. Di Giacomo ◽  
F. Latteri ◽  
C. Fichera ◽  
V. Sorrenti ◽  
A. Campisi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lipid Peroxidation ◽  
Xanthine Oxidase ◽  
Oxidase Activity ◽  
Rat Skeletal Muscle ◽  
Xanthine Oxidase Activity
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