Increased Release of Atrial Natriuretic Peptide by the Atria of Rats with Experimental Renal Failure

Nephron ◽  
1991 ◽  
Vol 57 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Norman L.M. Wong ◽  
Eric F.C. Wong
Keyword(s):  
Renal Failure ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Experimental Renal Failure ◽  
Atrial Natriuretic

scholarly journals Role of atrial natriuretic peptide in experimental renal failure.

1988 ◽  
Vol 52 (12) ◽  
pp. 1441-1445 ◽  
Author(s):  
TSUTOMU SANAKA ◽  
KEN TSUCHIYA ◽  
KOSAKU NITTA ◽  
MASAYOSHI SONE ◽  
NOBUHIRO SUGINO
Keyword(s):  
Renal Failure ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Experimental Renal Failure ◽  
Atrial Natriuretic

Atrial natriuretic peptide and adaptation of sodium urinary excretion in patients with chronic renal failure

1988 ◽  
Vol 75 (3) ◽  
pp. 243-249 ◽  
Author(s):  
Stanislas Czekalski ◽  
Catherine Michel ◽  
Jean-Claude Dussaule ◽  
Philippe Touraine ◽  
Francoise Mignon ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Sodium Excretion ◽  
Mean Blood Pressure ◽  
Group Iii ◽  
Sodium Load ◽  
Atrial Natriuretic

1. In order to examine the potential role of endogenous atrial natriuretic peptide (ANP) in modulating the increased sodium excretion per nephron in chronic renal failure, we studied healthy subjects with normal renal function (group I) and patients with moderate (group II) or severe chronic renal failure (group III) before, during and after administration of an intravenous sodium load. All subjects had been on a controlled diet containing 120 mmol of sodium per day for 5 days before the study. 2. Under basal conditions, plasma ANP and fractional excretion of sodium (FENa) were highest in group III. Both parameters increased in response to the sodium load in the three groups studied (P < 0.001). Changes with time differed from group to group (P < 0.05), the more marked response for both parameters being observed in group III. After adjustment with respect to plasma ANP (analysis of covariance), FENa was no longer modified in response to the sodium load, whereas adjustment of FENa with respect to mean blood pressure was without consequence on the significance of its change with time. This demonstrates that plasma ANP, but not mean blood pressure, represents the main factor producing variation in FENa during and after the sodium load. 3. These results suggest an important role for plasma ANP in promoting adaptation of short-term sodium excretion in response to an acute sodium load in patients with chronic renal failure who ingest a normal sodium intake.

scholarly journals Effects of atrial natriuretic peptide in clinical acute renal failure

1994 ◽  
Vol 45 (6) ◽  
pp. 1731-1738 ◽  
Author(s):  
S. Noor Rahman ◽  
Grace E. Kim ◽  
Alan S. Mathew ◽  
Carol A. Goldberg ◽  
Robin Allgren ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Atrial Natriuretic
Sign in / Sign up

Export Citation Format

Share Document