Behcet’s Syndrome Associated with Minimal Change Glomerulonephritis and Renal Vein Thrombosis

Nephron ◽  
1989 ◽  
Vol 52 (1) ◽  
pp. 87-89 ◽  
Author(s):  
G.H. Malik ◽  
L.A. Sirwal ◽  
K.A. Pandit
Keyword(s):  
Renal Vein ◽  
Renal Vein Thrombosis ◽  
Minimal Change ◽  
Behçet’S Syndrome ◽  
Behçet's Syndrome ◽  
Vein Thrombosis ◽  
Behcet’S Syndrome ◽  
Minimal Change Glomerulonephritis ◽  
Behcet's Syndrome

Comment on: Clinical course of acute deep vein thrombosis of the legs in Behçet’s syndrome: reply

Rheumatology ◽  
2020 ◽  
Vol 59 (4) ◽  
pp. 914-915 ◽  
Author(s):  
Yesim Ozguler ◽  
Gulen Hatemi ◽  
Firat Cetinkaya ◽  
Koray Tascilar ◽  
Vedat Hamuryudan ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Clinical Course ◽  
Behçet’S Syndrome ◽  
Behçet's Syndrome ◽  
Vein Thrombosis ◽  
Behcet’S Syndrome ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein ◽  
Behcet's Syndrome

Clinical course of acute deep vein thrombosis of the legs in Behçet’s syndrome

Rheumatology ◽  
2019 ◽  
Vol 59 (4) ◽  
pp. 799-806 ◽  
Author(s):  
Yesim Ozguler ◽  
Gulen Hatemi ◽  
Firat Cetinkaya ◽  
Koray Tascilar ◽  
Vedat Hamuryudan ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Relapse Rate ◽  
Doppler Ultrasonography ◽  
Behçet’S Syndrome ◽  
Behçet's Syndrome ◽  
Vein Thrombosis ◽  
Ifn Alpha ◽  
Behcet’S Syndrome ◽  
Deep Vein ◽  
Behcet's Syndrome

Abstract Objectives Lower extremity deep vein thrombosis (LEDVT) is a serious complication of Behçet’s syndrome. Management constitutes mainly of administration of immunosuppressives, but the predictors of relapse and the optimal choice of immunosuppressives remain unclear. In this prospective study, we aimed to detect the risk and predictors of relapse and treatment response to different modalities. Methods All Behçet’s syndrome patients who presented with a first episode of acute LEDVT between 2010 and 2014 were prospectively followed with a standard protocol. Acute LEDVT was confirmed by Doppler ultrasonography. Serial planned Doppler ultrasonography assessments were performed during follow-up and additionally repeated in case of clinical suspicion. Recanalization rate was assessed at each visit. Our first-line treatment strategy consisted of AZA and CSs. IFN-alpha was used in patients who were refractory to or could not tolerate AZA or had concomitant eye involvement requiring further treatment. Results Thirty-three patients with LEDVT (26 M/7 F) were prospectively followed for 40.7 ± 13.4 months. Among the 33 patients, 23 relapses were observed in 15 patients. Relapse rates were 29%, 37% and 45% at 6, 12 and 24 months, respectively. Among the possible predictors of relapse, poor recanalization was the only significant factor [hazard ratio 4.34 (95% CI 1.96, 10.0)]. Overall 29 patients were treated with AZA and 17 with IFN-alpha. The relapse rate was lower and recanalization rate was higher with IFN-alpha compared with AZA (12% vs 45% and 86% vs 45%). Conclusion The relapse rate for LEDVT in Behçet’s syndrome is high despite AZA treatment. IFN-alpha seems to be a promising agent for preventing LEDVT relapses and achieving good recanalization.

Behcet's syndrome

1970 ◽  
Vol 102 (1) ◽  
pp. 116-117 ◽  
Author(s):  
J. L. Fromer
Keyword(s):  
Behçet’S Syndrome ◽  
Behçet's Syndrome ◽  
Behcet’S Syndrome ◽  
Behcet's Syndrome
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