scholarly journals Cell Growth Inhibition, G2/M Cell Cycle Arrest, and Apoptosis Induced by Chloroquine in Human Breast Cancer Cell Line Bcap-37

2008 ◽  
Vol 22 (5-6) ◽  
pp. 431-440 ◽  
Author(s):  
Pei-du Jiang ◽  
Ying-lan Zhao ◽  
Wei Shi ◽  
Xiao-qiang Deng ◽  
Gang Xie ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cell Growth ◽  
Human Breast Cancer ◽  
Cancer Cell Line ◽  
Human Breast Cancer Cell ◽  
Human Breast ◽  
Cell Growth Inhibition ◽  
M Cell ◽  
Cycle Arrest

scholarly journals Inhibitory effect of isoamericanol A from Jatropha curcas seeds on the growth of MCF-7 human breast cancer cell line by G2/M cell cycle arrest

Heliyon ◽  
2016 ◽  
Vol 2 (1) ◽  
pp. e00055 ◽  
Author(s):  
Ayako Katagi ◽  
Li Sui ◽  
Kazuyo Kamitori ◽  
Toshisada Suzuki ◽  
Takeshi Katayama ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Human Breast Cancer ◽  
Cancer Cell Line ◽  
Inhibitory Effect ◽  
Human Breast Cancer Cell ◽  
Human Breast ◽  
M Cell ◽  
Cycle Arrest ◽  
Mcf 7

Identification of a 51-kilodalton calmodulin binding protein that changes during estrogen-stimulated cell growth

1990 ◽  
Vol 68 (5) ◽  
pp. 863-869 ◽  
Author(s):  
S. Laquerre ◽  
R. Poulin ◽  
F. Labrie ◽  
J. G. Chafouleas
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Human Breast Cancer ◽  
Binding Protein ◽  
Cancer Cell Line ◽  
Human Breast Cancer Cell ◽  
Two Dimensional ◽  
Human Breast ◽  
Calmodulin Binding ◽  
Isoelectric Points

Calmodulin-binding proteins (CaMBPs) were analyzed during estrogen-stimulated growth in the human breast cancer cell line ZR-75-1. A variety of Ca2+-dependent and -independent CaMBPs were observed to be present in these cells. Calmodulin (CaM) binding to a 51-kilodalton protein was shown to be Ca2+-dependent. Moreover, binding to this protein was reduced in the estrogen-treated cells. This effect occurred early during estrogen-stimulated cell growth and was maintained during exponential growth in the presence of estrogen. 125I-labeled CaM overlay procedure of two-dimensional polyacrylamide gels reveals that this 51-kilodalton protein is composed of at least two distinct isoforms with different isoelectric points. Subcellular localization demonstrates that this protein resides exclusively in the microsomal fraction.Key words: calmodulin, calmodulin-binding protein, estrogen-stimulated cell growth.

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