Physiopathology and Clinical Aspects of Diabetic Nephropathy

Nephron ◽  
1988 ◽  
Vol 50 (2) ◽  
pp. 151-163 ◽  
Author(s):  
Alessandro Castiglioni ◽  
Giorgio M. Savazzi
Keyword(s):  
Diabetic Nephropathy ◽  
Clinical Aspects

scholarly journals Diabetic nephropathy: Clinical aspects and risk factors

2019 ◽  
Vol 11 (3) ◽  
pp. e369
Author(s):  
Ramla Mizouri ◽  
Hajer Zahra ◽  
Imen Sebai ◽  
Marwa Khiari ◽  
Fatma Boukhayatia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diabetic Nephropathy ◽  
Clinical Aspects

Novel insights into the pathophysiology and clinical aspects of diabetic nephropathy

2017 ◽  
Vol 18 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Zubair Ilyas ◽  
Joumana T. Chaiban ◽  
Armand Krikorian
Keyword(s):  
Diabetic Nephropathy ◽  
Clinical Aspects

scholarly journals 3. Clinical Aspects of Diabetic Nephropathy

2016 ◽  
Vol 105 (3) ◽  
pp. 482-487
Author(s):  
Takashi Wada
Keyword(s):  
Diabetic Nephropathy ◽  
Clinical Aspects

Clinical aspects of reactive oxygen and nitrogen species

2004 ◽  
Vol 71 ◽  
pp. 121-133 ◽  
Author(s):  
Ascan Warnholtz ◽  
Maria Wendt ◽  
Michael August ◽  
Thomas Münzel
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Risk Factor ◽  
Endothelial Dysfunction ◽  
Vascular Tissue ◽  
Rapid Development ◽  
Reactive Oxygen ◽  
Clinical Aspects ◽  
No Production ◽  
Oxygen Species

Endothelial dysfunction in the setting of cardiovascular risk factors, such as hypercholesterolaemia, hypertension, diabetes mellitus and chronic smoking, as well as in the setting of heart failure, has been shown to be at least partly dependent on the production of reactive oxygen species in endothelial and/or smooth muscle cells and the adventitia, and the subsequent decrease in vascular bioavailability of NO. Superoxide-producing enzymes involved in increased oxidative stress within vascular tissue include NAD(P)H-oxidase, xanthine oxidase and endothelial nitric oxide synthase in an uncoupled state. Recent studies indicate that endothelial dysfunction of peripheral and coronary resistance and conductance vessels represents a strong and independent risk factor for future cardiovascular events. Ways to reduce endothelial dysfunction include risk-factor modification and treatment with substances that have been shown to reduce oxidative stress and, simultaneously, to stimulate endothelial NO production, such as inhibitors of angiotensin-converting enzyme or the statins. In contrast, in conditions where increased production of reactive oxygen species, such as superoxide, in vascular tissue is established, treatment with NO, e.g. via administration of nitroglycerin, results in a rapid development of endothelial dysfunction, which may worsen the prognosis in patients with established coronary artery disease.

Clinical Aspects of the Hepatic Circulation

1965 ◽  
Vol 48 (6) ◽  
pp. 790-804 ◽  
Author(s):  
Carroll M. Leevy
Keyword(s):  
Clinical Aspects ◽  
Hepatic Circulation

Abstract # P-17: Association of NQO1 (Rs1800566) Polymorphism with NQO1 Levels and Risk of Diabetic Nephropathy in Indian Population

2016 ◽  
Vol 22 ◽  
pp. 21
Author(s):  
Mohini Sharma ◽  
S. Gupta ◽  
M. Mehndiratta ◽  
O.P. Kalra ◽  
R. Shukla ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Indian Population
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