scholarly journals Evidence of an Increased Susceptibility to Lipid Peroxidation in Red Blood Cells of Chronic Renal Failure Patients

Nephron ◽  
1988 ◽  
Vol 50 (1) ◽  
pp. 64-65 ◽  
Author(s):  
Amparo Miguel ◽  
Alicia Miguel ◽  
Mariano Linares ◽  
Alfonso Perez ◽  
Rosa Moll ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Increased Susceptibility

Metabolism of Red Blood Cells in Chronic Renal Failure

Nephron ◽  
1979 ◽  
Vol 24 (1) ◽  
pp. 21-24 ◽  
Author(s):  
J.L. Rodríguez-Commes ◽  
J.M. Tabernero ◽  
P. Martin-Vasallo ◽  
S. DeCastro ◽  
E. Battaner
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells

scholarly journals HAEMATOLOGICAL PARAMETERS AMONG SUDANESE PATIENTS WITH CHRONIC RENAL FAILURE

2016 ◽  
Vol 4 (1) ◽  
pp. 50-54
Author(s):  
RaianBakhet Yassein ◽  
Nada Omer Alseedig ◽  
SihamKhalifaAbd Allah ◽  
AreegAlsail Mohmmed ◽  
NosibaAbdelmajid Alballah ◽  
...  
Keyword(s):  
Renal Failure ◽  
Platelet Count ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
White Blood Cells ◽  
Haemoglobin Concentration ◽  
Haematological Parameters ◽  
Common Causes ◽  
Hb Concentration

Chronic renal failure is one of the more common causes of morbidity and mortality among Sudanese. This study describes altered haemoglobin concentration (Hb), haematochrit percent (Hct), red blood cells count (RBCs), platelet count (Plts) and white blood cells count (WBCs) in patients with chronic renal failure and describes the effect of disease duration on haemoglobin concentration and red blood cells count. Methods: Haematological parameters in (50) patients with Chronic renal failure and (50) age and sex matched controls were evaluated, living in Shendi locality in northern Sudan. The results of this study showed that mean of Hb concentration, RBCs count, Hct percent and platelet count were exhibited significant decreased, but mean of WBCs count was insignificantly increased. Increased duration of the disease lead to significantly decreased on mean of Hb concentration and RBCs count. Chronic renal failure is associated with different degrees of reduced haematological parameters. Also increase duration of the disease lead to significantly decrease in mean of Hb concentration and RBCs count.

The effect of erythropoietin on the cellular defence mechanism of red blood cells in children with chronic renal failure

1992 ◽  
Vol 6 (6) ◽  
pp. 536-541 ◽  
Author(s):  
S�ndor T�ri ◽  
Ilona N�meth ◽  
Ilona Varga ◽  
Tibor Bodrogi ◽  
B�la Matkovics
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Defence Mechanism ◽  
Cellular Defence

scholarly journals Potassium concentration of red blood cells in patients with acute or chronic renal failure.

1990 ◽  
Vol 23 (12) ◽  
pp. 1349-1355
Author(s):  
Shigehiro Miki ◽  
Shigekazu Yuasa ◽  
Takafumi Yura ◽  
Tooru Sumikura ◽  
Norihiro Takahashi ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Potassium Concentration

Physical Properties of the Red Blood Cells in Chronic Renal Failure

Nephron ◽  
1991 ◽  
Vol 59 (2) ◽  
pp. 271-278 ◽  
Author(s):  
M. Viljoen ◽  
A.A. de Oliveira ◽  
F.J. Milne
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Physical Properties ◽  
Red Blood Cells ◽  
Blood Cells

The protective effect of olive cake treatment on oxidant/antioxidant biomarkers, on serum, red blood cells and liver, in streptozotocin-induced diabetic rats fed cholesterol-enriched diet

2019 ◽  
Vol 50 (4) ◽  
pp. 785-798
Author(s):  
Yahiaoui Zidan ◽  
Sherazede Bouderbala ◽  
Cherrad Hayet ◽  
Bouchenak Malika
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Enzymes ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Diabetic Rats ◽  
Male Rats ◽  
Olive Cake ◽  
Content Type ◽  
Enzymes Activities ◽  
Antioxidant Enzymes Activities

Purpose The purpose of this study is to determine the effect of olive cake (OC) on lipid peroxidation as well as antioxidant enzymes activities of serum, red blood cells (RBCs) and liver, in streptozotocin (STZ)-induced-diabetic rat fed cholesterol-enriched diet. Design/methodology/approach Hypercholesterolemic male rats were rendered diabetic (HC-D) by a single intraperitoneal injection dose of STZ (35 mg/kg BW). HC-D rats were divided into two groups fed for 28d a diet supplemented with OC at 7.5 percent (HC-D-OC) or not (HC-D). A control group (C) was submitted to standard diet containing 20 per cent casein for the same experimental period. Findings RBCs, serum and liver thiobarbituric acid reactive substances (TBARS) contents were significantly increased in HC-D, compared to C group (p = 0.04, p = 0.02 and 0.03). These values were significantly decreased (48 per cent and 64 per cent; p = 0.02 and p = 0.0007) in serum and liver of HC-D-OC vs HC-D group. In RBCs, superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferase (GST) activities were, respectively, 1.5, 2- and 1.7-fold higher (p = 0.03, p = 0.008 and p = 0.03) in HC-D group compared to HC group. In serum and liver, SOD, CAT and GST activities were, respectively, 1.3-, 2.6- and 1.6-fold increased (p = 0.03, p = 0.007 and p = 0.02). In HC-D-OC compared to HC-D group, RBCs glutathione peroxidase (GSH-Px), CAT and GST activities were, respectively, 2.1-, 3.3- and 2.1-fold higher (p = 0.04, p = 0.0009 and p = 0.03). In serum, SOD and CAT activities were, respectively, 1.5- and 1.9-fold increased (p = 0.02, p = 0.02). In liver, SOD, GSH-PX, CAT and GST activities were significantly increased (p = 0.005, p = 0.03, p = 0.02 and p = 0.04). Originality/value In diabetic rats-fed cholesterol-enriched diet, OC was able to reduce oxidative stress by decreasing lipid peroxidation and increasing antioxidant enzymes activities in serum, RBCs and liver.

In vitro aging of red blood cells and lipid peroxidation

1987 ◽  
Vol 60 (1-3) ◽  
pp. 163-166 ◽  
Author(s):  
Hermann Einsele ◽  
Michael R. Clemens ◽  
Herbert Remmer
Keyword(s):  
Lipid Peroxidation ◽  
Red Blood Cells ◽  
Blood Cells ◽  
In Vitro Aging

scholarly journals Detection of short-chain carbonyl products of lipid peroxidation from malaria-parasite (Plasmodium vinckei)-infected red blood cells exposed to oxidative stress

1988 ◽  
Vol 249 (1) ◽  
pp. 63-68 ◽  
Author(s):  
G D Buffinton ◽  
N H Hunt ◽  
W B Cowden ◽  
I A Clark
Keyword(s):  
Lipid Peroxidation ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Malaria Parasite ◽  
Radical Scavenger ◽  
Parasite Plasmodium ◽  
Infected Rbcs ◽  
Carbonyl Products ◽  
Plasmodium Vinckei

Reversed-phase h.p.l.c. was used to detect 2,4-dinitrophenylhydrazine-reactive carbonyl products, which excludes malonaldehyde, in malaria-parasite (Plasmodium vinckei)-infected murine red blood cells (RBCs). A number of alkanals, 4-hydroxyalk-2-enals and alka-2,4-dienals were tentatively identified by comparison with authentic standards. The formation of 4-hydroxynon-2-enal, deca-2,4-dienal and hexanal was greater in P. vinckei-infected RBCs than in their uninfected counterparts and was increased by the presence of t-butyl hydroperoxide. Several of these aldehydes have previously been shown to be toxic to various types of cells, including P. falciparum, in vitro. The iron chelator desferrioxamine and the free-radical scavenger butylated hydroxyanisole inhibited the formation of these aldehydes. These experiments demonstrate that products of lipid peroxidation other than malonaldehyde are formed during the exposure of malaria-infected RBCs in vitro to drugs that generate reactive oxygen species and have anti-parasitic activity. The formation of products of this type during the natural course of malaria infection may have implications for the mechanisms underlying intra-RBC parasite death and the tissue damage associated with the disease.

Sign in / Sign up

Export Citation Format

Share Document