Characteristics of the Peritoneal Mass Transfer of Parathormone in Patients under Continuous Ambulatory Peritoneal Dialysis Therapy

Nephron ◽  
1984 ◽  
Vol 37 (1) ◽  
pp. 21-24 ◽  
Author(s):  
A. Rodríguez-Carmona ◽  
R. Selgas ◽  
M.E. Martínez ◽  
F. Ortí ◽  
J.L. Miguel ◽  
...  
2000 ◽  
Vol 35 (4) ◽  
pp. 761-766 ◽  
Author(s):  
Yoshifumi Ubara ◽  
Hideyuki Katori ◽  
Tetsuo Tagami ◽  
Masafumi Yokota ◽  
Akiko Kitamura ◽  
...  

1995 ◽  
Vol 15 (1) ◽  
pp. 65-70 ◽  
Author(s):  
María E. Martinez ◽  
Maria T. Del Campo ◽  
Maria J. Sánchez-Cabezudo ◽  
Gloria Balaguer ◽  
Ana Rodriguez-Carmona ◽  
...  

Objectives To evaluate calcidiol serum levels in a group of continuous ambulatory peritoneal dialysis (CAPO) patients and the effect of oral calcidiol treatment on serum levels and peritoneal losses. Study design Twenty patients (13 female, 7 male) were studied for 12 –60 months. Their ages ranged 22 72 years (mean 46±15). Serum calcidiol, total protein and urea were determined at baseline and after the administration per os of 0.133 mcg/day of calcidiol for 10 days. At the same time, calcidiol and total protein were measured in peritoneal effluent at baseline and at 5,10, and 40 days after starting this treatment. Results A significant and direct correlation between the calcidiol dialysis/plasma ratio and the peritoneal protein losses was found, both before and 40 days after calcidiol administration when calcidiol serum levels were the lowest. As calcidiol serum levels rose to the normal range in the course of the study, peritoneal losses of this metabolite increased slightly and correlated with calcidiol serum levels and urea mass transfer coefficient (MTC); the significant correlation between calcidiol serum levels and peritoneal protein losses disappeared. Conclusions When serum calcidiol levels are low, calcidiol peritoneal losses in patients on CAPO correlate with protein peritoneal losses. However, when serum calcidiollevels rise, the calcidiol peritoneal losses correlate with calcidiol serum levels and urea MTC, and not with protein peritoneal losses.


2003 ◽  
Vol 23 (2_suppl) ◽  
pp. 132-133 ◽  
Author(s):  
Masaaki Nakayama ◽  
Masato Ikeda ◽  
Naohiko Katoh ◽  
Keitaro Yokoyama ◽  
Hiroyasu Yamamoto ◽  
...  

Encapsulating peritoneal sclerosis (EPS) is undoubtedly the most serious complication of continuous ambulatory peritoneal dialysis treatment in Japan, with a mortality rate ranging from about 39% to 49% in reported series. Cases of EPS have been linked to long-term peritoneal dialysis, and limitations on renal transplantation in Japan mean that most Japanese patients have to accept long-term dialysis therapy, which is a critical problem. Treatment alternatives for EPS include total parenteral nutrition, prednisolone administration, and surgical approaches, all of which have varying success rates. Additional therapeutic and new preventive measures have to be established for EPS.


1990 ◽  
Vol 10 (2) ◽  
pp. 141-145 ◽  
Author(s):  
Dirk G. Struijk ◽  
Raymond T. Krediet ◽  
Gerardus C. M. Koomen ◽  
Elisabeth W. Boeschoten ◽  
Hendrik J. Vd Reijden ◽  
...  

To elucidate the importance of possible trapping of macromolecules in peritoneal tissue on the calculation of peritoneal lymphatic drainage, we compared the transport of inulin administered i.v. and i.p. in nine continuous ambulatory peritoneal dialysis (CAPD) patients on two separate days. In the intraperitoneal study inulin (5 g) was added to the dialysate and in the intravenous study inulin (5 g) was given i.v. 3 h before the test. No differences were found in the mass transfer area coefficients (MTC) of urea, creatinine, and glucose between the two tests. The MTC after inulin i.p. was 3.2 ± 0.7 mLlmin (mean ± SD) and after inulin i.v. 1.8 ± 0.5 (p < 10-5). As the difference in transport kinetics between i.v. and i.p. administration is likely to be caused by lymphatic absorption, a mean lymphatic flow of 1.4 mLlmin could be calculated. This value corresponds to the data obtained with macromolecules. Our results therefore favor the hypothesis that no local accumulation of macromolecules in the peritoneal tissues takes place and that their disappearance from the peritoneal cavity represents lymphatic absorption.


1984 ◽  
Vol 18 ◽  
pp. 361A-361A ◽  
Author(s):  
Michael Freundlich ◽  
Gaston Zilleruelo ◽  
Carolyn Abitbol ◽  
Kuo H Hwang ◽  
Jacques J Bourgoignie ◽  
...  

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