scholarly journals Diurnal Variation of Serum Alpha-1-Microglobulin in Normal Subjects

Nephron ◽  
1981 ◽  
Vol 29 (3-4) ◽  
pp. 204-204 ◽  
Author(s):  
Y. Itoh
1966 ◽  
Vol 112 (493) ◽  
pp. 1263-1267 ◽  
Author(s):  
R. J. Doig ◽  
R. V. Mummery ◽  
M. R. Wills ◽  
A. Elkes

Sleep disturbance is commonly found in depression. Plasma cortisol levels in non-hospitalized normal subjects show a rise prior to waking, with peak values at between 5 and 8 a.m. (9, 10). In a group of eight normal subjects, Perkoff (10) changed the sleep rhythm to sleeping during the day, using darkened rooms, and found that the plasma cortisol level followed suit, rising sharply in the two-hour period before waking. He stated: “A fundamental characteristic of the diurnal variation of plasma 17 OHCS concentration is the abrupt rise which occurs during the sleep period.”


1969 ◽  
Vol 62 (1_Suppl) ◽  
pp. S185-S206 ◽  
Author(s):  
Brij B. Saxena ◽  
Gerhard Leyendecker ◽  
Weiyu Chen ◽  
Hortense M. Gandy ◽  
Ralph E. Peterson

ABSTRACT Procedure for the radioimmunoassay of FSH and LH using chromatoelectrophoresis for the separation of antibody-bound and free labeled hormone is described. Diurnal variation in FSH and LH levels of normal men and women in follicular and luteal phases of the cycle is reported. The diurnal variation was not abolished in three women taking contraceptive medication and in two women in postmenopause. The diurnal variation of FSH and LH in plasma is compared with that of cortisol, dehydroepiandrosterone and testosterone. It is suggested that diurnal variation of FSH and LH may be independent of a normally functioning pituitary-gonadal axis; however, steroidal feed-back may have a regulatory effect on the magnitude of the diurnal variation. The plasma levels of FSH and LH in normal subjects during normal menstrual cycles as well as in patients with endocrinopathies obtained in our laboratory by radioimmunoassay are compared with those obtained by both radioimmunoassay and bioassay by other investigators.


1956 ◽  
Vol 16 (5) ◽  
pp. 622-633 ◽  
Author(s):  
CLAUDE J. MIGEON ◽  
FRANK H. TYLER ◽  
JOHN P. MAHONEY ◽  
ANGEL A. FLORENTIN ◽  
HILMON CASTLE ◽  
...  

1995 ◽  
Vol 96 (5) ◽  
pp. 643-651 ◽  
Author(s):  
Koichiro Asano ◽  
Craig M. Lilly ◽  
Walter J. O'Donnell ◽  
Elliot Israel ◽  
Andrew Fischer ◽  
...  

1978 ◽  
Vol 55 (6) ◽  
pp. 523-527 ◽  
Author(s):  
J. R. M. Bateman ◽  
D. Pavia ◽  
S. W. Clarke

1. Mucociliary clearance has been measured over a 6 h period by using the radioaerosol technique in seven normal male subjects lying supine, both during the day when awake, and during the night when asleep. 2. The percentage of radioaerosol cleared during the night, when asleep, was significantly less than during the day when awake (P < 0.02). 3. A comparison of radioaerosol clearance before and after the time of onset of sleep demonstrates that reduced clearance occurred during sleep, indicating that this is probably a sleep-related phenomenon and not merely a result of diurnal variation. 4. This finding has important implications for patients with chronic bronchitis or asthma, in whom early morning cough or wheeze may be a predominant feature.


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