Correlation between Laser Doppler Perfusion Monitoring and Hematocrit in Hamster Cheek Pouch Microcirculation

1997 ◽  
Vol 17 (1) ◽  
pp. 33-40 ◽  
Author(s):  
A. Colantuoni ◽  
Silvia Bertuglia
Keyword(s):  
Laser Doppler ◽  
Cheek Pouch ◽  
Hamster Cheek Pouch ◽  
Laser Doppler Perfusion Monitoring

scholarly journals Perchloric acid-soluble proteins from goat liver inhibit chemical carcinogenesis of Syrian hamster cheek-pouch carcinoma

1998 ◽  
Vol 79 (1) ◽  
pp. 54-58 ◽  
Author(s):  
F Ghezzo ◽  
G N Berta ◽  
B Bussolati ◽  
A Bosio ◽  
G Corvetti ◽  
...  
Keyword(s):  
Perchloric Acid ◽  
Syrian Hamster ◽  
Chemical Carcinogenesis ◽  
Soluble Proteins ◽  
Cheek Pouch ◽  
Hamster Cheek Pouch

scholarly journals Signaling via β2 Integrins Triggers Neutrophil-Dependent Alteration in Endothelial Barrier Function

2000 ◽  
Vol 191 (11) ◽  
pp. 1829-1840 ◽  
Author(s):  
Narinder Gautam ◽  
Heiko Herwald ◽  
Per Hedqvist ◽  
Lennart Lindbom
Keyword(s):  
Protein S ◽  
Endothelial Barrier ◽  
Cheek Pouch ◽  
Cross Linking ◽  
Endothelial Lining ◽  
Hamster Cheek Pouch ◽  
Cationic Protein ◽  
Edema Formation ◽  
Β2 Integrins

Activation of polymorphonuclear leukocytes (PMNs) and adhesion to the endothelial lining is a major cause of edema formation. Although known to be dependent on the function of β2 integrins (CD11/CD18), the precise mechanisms by which adherent PMNs may impair endothelial barrier capacity remain unclear. Here, the role of transmembrane signaling by β2 integrins in PMN-induced alterations in tight junctional permeability of cultured endothelial cell (EC) monolayers was investigated. PMN activation, in the absence of proinflammatory stimuli, was accomplished through antibody cross-linking of CD11b/CD18, mimicking adhesion-dependent receptor engagement. CD18 cross-linking in PMNs added to the EC monolayer provoked a prompt increase in EC permeability that coincided with a rise in EC cytosolic free Ca2+ and rearrangement of actin filaments, events similar to those evoked by chemoattractant PMN activation. Cell-free supernatant obtained after CD18 cross-linking in suspended PMNs triggered an EC response indistinguishable from that induced by direct PMN activation, and caused clear-cut venular plasma leakage when added to the hamster cheek pouch in vivo preparation. The PMN-evoked EC response was specific to β2 integrin engagement inasmuch as antibody cross-linking of l-selectin or CD44 was without effect on EC function. Our data demonstrate a causal link between outside-in signaling by β2 integrins and the capacity of PMNs to induce alterations in vascular permeability, and suggest a paracrine mechanism that involves PMN-derived cationic protein(s) in the cellular crosstalk between PMNs and ECs.

The Influence of Probe Fiber Distance on Laser Doppler Perfusion Monitoring Measurements

2003 ◽  
Vol 10 (5) ◽  
pp. 433-441 ◽  
Author(s):  
FERNANDO MORALES ◽  
REINDERT GRAAFF ◽  
ANDRIES J. SMIT ◽  
RODNEY GUSH ◽  
GERHARD RAKHORST
Keyword(s):  
Laser Doppler ◽  
Laser Doppler Perfusion Monitoring

Pyran copolymer and 7,12-dimethylbenzanthraceneinduced carcinogenesis in the hamster cheek pouch

1981 ◽  
Vol 26 (10) ◽  
pp. 761-767 ◽  
Author(s):  
A.R. Gould ◽  
C.H. Miller ◽  
A.H. Kafrawy
Keyword(s):  
Cheek Pouch ◽  
Hamster Cheek Pouch
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