Effect of Dietary Vitamin E on the Vitamin E Status in the BB Rat during Development and after the Onset of Diabetes

1986 ◽  
Vol 30 (3) ◽  
pp. 157-165 ◽  
Author(s):  
Willy A. Behrens ◽  
Fraser W. Scott ◽  
René Madère ◽  
Keith Trick ◽  
Karen Hanna
Keyword(s):  
Vitamin E ◽  
Dietary Vitamin ◽  
Bb Rat ◽  
Onset Of Diabetes ◽  
Vitamin E Status

scholarly journals Research Note: Vitamin E Status of Turkey Poults as Influenced by Different Dietary Vitamin E Sources, a Bile Salt, and an Antioxidant

1993 ◽  
Vol 72 (6) ◽  
pp. 1184-1188 ◽  
Author(s):  
MARIA F. SOTO-SALANOVA ◽  
JERRY L. SELL ◽  
EMMA G. MALLARINO ◽  
F. JAVIER PIQUER ◽  
DARRYL L. BARKER ◽  
...  
Keyword(s):  
Vitamin E ◽  
Bile Salt ◽  
Research Note ◽  
Dietary Vitamin ◽  
Turkey Poults ◽  
Vitamin E Status

scholarly journals The effect of dietary vitamin E and fatty acid supplementation of pregnant and lactating ewes on placental and mammary transfer of vitamin E to the lamb

2005 ◽  
Vol 93 (4) ◽  
pp. 549-557 ◽  
Author(s):  
Judith L. Capper ◽  
Robert G. Wilkinson ◽  
Eleni Kasapidou ◽  
Sandra E. Pattinson ◽  
Alexander M. Mackenzie ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Vitamin E ◽  
Fish Oil ◽  
Plasma Concentrations ◽  
Dietary Vitamin ◽  
Blood Samples ◽  
Fatty Acid Supplementation ◽  
Fish Oil Supplementation ◽  
Vitamin E Status ◽  
Vitamin E Supplementation

The present study investigated the effect of maternal vitamin E and fatty acid supplementation on lamb antioxidant status. Forty-eight ewes were fed one of four concentrate diets supplemented with a basal (50 mg/kg) or supranutritional (500 mg/kg) level of vitamin E plus a source of either saturated fat (Megalac®; Volac Ltd, Royston, Hertfordshire, UK) or long-chain PUFA (fish oil) from 6 weeks prepartum until 4 weeks postpartum. Blood samples were taken from ewes and lambs at intervals throughout the experiment and, at parturition, muscle, brain and blood samples were obtained from twelve lambs (three per treatment). Colostrum and milk samples were obtained at 12 h and 21 d after parturition, respectively. Supranutritional vitamin E supplementation of the ewe significantly increased concentrations of vitamin E in neonatal lamb tissues although plasma concentrations were undetectable. A significant increase in lamb birth weight resulted from increasing the dietary vitamin E supply to the ewe. Furthermore, maternal plasma, colostrum and milk vitamin E concentrations were increased by vitamin E supplementation, as were lamb plasma concentrations at 14 d of age. Neonatal vitamin E status was not significantly affected by fat source although plasma vitamin E concentrations in both ewes and suckling lambs were reduced by fish oil supplementation of the ewe. Fish oil supplementation reduced vitamin E concentrations in colostrum and milk and the activity of glutathione peroxidase in suckling lambs. The data suggest that the vitamin E status of the neonatal and suckling lamb may be manipulated by vitamin E supplementation of the ewe during pregnancy and lactation.

The effect of excessive dietary vitamin A on performance and vitamin E status in swine fed diets varying in dietary vitamin E

1995 ◽  
Vol 73 (4) ◽  
pp. 1093-1098 ◽  
Author(s):  
L. E. Anderson ◽  
R. O. Myer ◽  
J. H. Brendemuhl ◽  
L. R. McDowell
Keyword(s):  
Vitamin E ◽  
Vitamin A ◽  
Dietary Vitamin ◽  
Vitamin E Status

The effect of vitamin E and long-chain polyunsaturated fatty acid supplementation of pregnant and lactating ewes on the transfer of vitamin E to the lamb

2003 ◽  
Vol 2003 ◽  
pp. 61-61
Author(s):  
J. L. Capper ◽  
R. G. Wilkinson ◽  
E. Kasapidou ◽  
S. E. Pattinson ◽  
A. M. Mackenzie ◽  
...  
Keyword(s):  
Vitamin E ◽  
Maternal Diet ◽  
Dietary Vitamin ◽  
Chain Polyunsaturated Fatty Acid ◽  
Biochemical Mechanism ◽  
Pufa Supplementation ◽  
Fatty Acid Supplementation ◽  
Chain Pufa ◽  
Vitamin E Status ◽  
Long Chain

It is reported that supplementing pregnant ewes with supra-optimal levels of vitamin E improves neonatal lamb vigour and growth rate (Merrell, 1998). The biochemical mechanism behind these observations has yet to be elucidated as several studies report negligible placental vitamin E transfer in ruminants (Van Saun et al., 1989); consequently, lambs may be clinically deficient in this nutrient at birth and achieve a satisfactory vitamin E status via colostrum ingestion. Lamb vitamin E status may be further diminished by the addition of polyunsaturated fatty acids (PUFAs) to the maternal diet. However, PUFA supplementation demonstrably enhances foetal and neonatal development in human studies (Morley, 1998) although these effects have not been investigated in ruminants to any depth. The objective of this experiment was to investigate the effects of dietary vitamin E in combination with long-chain PUFA supplementation of ewes on ewe and lamb performance.

scholarly journals Glutathione peroxidase activity and erythrocyte stability in calves differing in selenium and vitamin E status

1968 ◽  
Vol 46 (2) ◽  
pp. 345-355 ◽  
Author(s):  
R. C. Siddons ◽  
C. F. Mills
Keyword(s):  
Vitamin E ◽  
Glutathione Peroxidase ◽  
Peroxidase Activity ◽  
Dietary Vitamin ◽  
Plasma Vitamin ◽  
Glutathione Peroxidase Activity ◽  
Bull Calves ◽  
Plasma Vitamin E ◽  
Erythrocyte Stability ◽  
Vitamin E Status

1. Glutathione peroxidase activity (EC1.11.1.9) and erythrocyte stability were measured in Friesian bull calves which were given for 36 weeks semi-purified diets either adequate or low in selenium or vitamin E or both.2. Dietary Se or vitamin E content had no effect on growth rate and haematological vaiues. None of the calves exhibited clinical deficiency symptoms and serum aspartate amino transferase (EC 2.6.1.1) and creatine phosphokinase (EC 2.7.3.2) activities remained normal. Heart and skeletal muscles of all calves appeared macroscopically and microscopically normal at autopsy.3. Glutathione peroxidase activity in plasma, blood and other tissues, except the testis, was significantly lower in calves receiving low dietary Se but was independent of dietary vitamin E content.4. Plasma vitamin E levels decreased rapidly and to very low levels in calves given low vitamin E diets irrespective of the Se content of the diet.5. A low dietary vitamin E intake increased the susceptibility of erythrocytes to auto- and peroxidative haemolysis whereas a low Se intake in the presence of adequate vitamin E did not. However, erythrocytes from calves receiving low Se and low vitamin E were more susceptible to peroxidative haemolysis than erythrocytes from calves receiving low vitamin E and adequate Se. The effect of dietary vitamin E content on osmotic haemolysis induced by hypotonic saline was variable.6. The results suggest that measurement of blood glutathione peroxidase activity and the susceptibility of erythrocytes to auto- or peroxidative haemolysis could be used for the differential diagnosis of subclinical Se and vitamin E deficiency in ruminants.

Dietary Vitamin E Status Dictates Oxidative Stress Outcomes by Modulating Effects of Fish Oil Supplementation in Alzheimer Disease Model APPswe/PS1dE9 Mice

2018 ◽  
Vol 55 (12) ◽  
pp. 9204-9219 ◽  
Author(s):  
Shengqi Dong ◽  
Xiaochen Huang ◽  
Jie Zhen ◽  
Nicholas Van Halm-Lutterodt ◽  
JiaJia Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Alzheimer Disease ◽  
Fish Oil ◽  
Disease Model ◽  
Dietary Vitamin ◽  
Fish Oil Supplementation ◽  
Vitamin E Status

scholarly journals Breeder Diet Strategies for Generating Ttpa-Null and Wild-Type Mice with Low Vitamin E Status to Assess Neurological Outcomes

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Katherine M Ranard ◽  
Matthew J Kuchan ◽  
John W Erdman
Keyword(s):  
Animal Model ◽  
Vitamin E ◽  
Mouse Model ◽  
Wild Type ◽  
Future Studies ◽  
Neurological Outcomes ◽  
Transfer Protein ◽  
And Function ◽  
The Brain ◽  
Vitamin E Status

ABSTRACT Studying vitamin E [α-tocopherol (α-T)] metabolism and function in the brain and other tissues requires an animal model with low α-T status, such as the transgenic α-T transfer protein (Ttpa)–null (Ttpa−/−) mouse model. Ttpa+/− dams can be used to produce Ttpa−/− and Ttpa+/+mice for these studies. However, the α-T content in Ttpa+/− dams’ diet requires optimization; diets must provide sufficient α-T for reproduction, while minimizing the transfer of α-T to the offspring destined for future studies that require low baseline α-T status. The goal of this work was to assess the effectiveness and feasibility of 2 breeding diet strategies on reproduction outcomes and offspring brain α-T concentrations. These findings will help standardize the breeding methodology used to generate the Ttpa−/− mice for neurological studies.

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