Acute Effects of Ethanol and Its Metabolites on Plasma Lipids and Lipoprotein Lipase Activity

1983 ◽  
Vol 27 (4) ◽  
pp. 328-337 ◽  
Author(s):  
Per Hansson ◽  
Peter Nilsson-Ehle
Keyword(s):  
Lipoprotein Lipase ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Lipoprotein Lipase Activity ◽  
Acute Effects

Regulation of lipoprotein lipase activity in cardiac myocytes from control and diabetic rat hearts by plasma lipids

1992 ◽  
Vol 70 (9) ◽  
pp. 1271-1279 ◽  
Author(s):  
Brian Rodrigues ◽  
Janice E. A. Braun ◽  
Michael Spooner ◽  
David L. Severson
Keyword(s):  
Lipoprotein Lipase ◽  
Cardiac Myocytes ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Inhibitory Effect ◽  
Diabetic Rats ◽  
Diabetic Rat ◽  
Lipoprotein Lipase Activity ◽  
Triton Wr 1339 ◽  
Plasma Triacylglycerol

The objective of this investigation was to test the hypothesis that the diabetes-induced reduction in lipoprotein lipase activity in cardiac myocytes may be due to hypertriglyceridemia. Administration of 4-aminopyrazolopyrimidine (50 mg/kg) to control rats for 24 h reduced plasma triacylglycerol levels and increased the heparin-induced release of lipoprotein lipase into the incubation medium of cardiac myocytes. The acute (3–5 days) induction of diabetes by streptozotocin (100 mg/kg) produced hypertriglyceridemia and reduced heparin-releasable lipoprotein lipase activity in cardiac myocytes. Treatment of diabetic rats with 4-aminopyrazolopyrimidine resulted in a fall in plasma triacylglycerol content and increased heparin-releasable lipoprotein lipase activity. Administration of Triton WR-1339 also resulted in hypertriglyceridemia, but the heparin-induced release of lipoprotein lipase from control cardiac myocytes was not reduced in the absence of lipolysis of triacylglycerol-rich lipoproteins. Treatment with Triton WR-1339 did, however, increase the heparin-induced release of lipoprotein lipase from diabetic cardiac myocytes. Preparation of cardiac myocytes with 0.9 mM oleic acid resulted in a decrease in both total cellular and heparin-releasable lipoprotein lipase activities. These results suggest that the diabetes-induced reduction in heart lipoprotein lipase activity may, at least in part, be due to an inhibitory effect of free fatty acids, derived either from lipoprotein degradation or from adipose tissue lipolysis, on lipoprotein lipase activity in (and (or) release from) cardiac myocytes.Key words: diabetes, plasma triacylglycerols, cardiac myocytes, lipoprotein lipase.

scholarly journals Effect of Oolong Tea on Plasma Lipids and Lipoprotein Lipase Activity in Young Women.

1991 ◽  
Vol 44 (4) ◽  
pp. 251-259 ◽  
Author(s):  
Kazuko IWATA ◽  
Takayo INAYAMA ◽  
Satomi MIWA ◽  
Kazuo KAWAGUCHI ◽  
Goro KOIKE
Keyword(s):  
Lipoprotein Lipase ◽  
Young Women ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Lipoprotein Lipase Activity ◽  
Oolong Tea

Plasma lipids and lipoprotein lipase activity in Kawasaki syndrome (KS)

1992 ◽  
Vol 1 (1) ◽  
pp. 76 ◽  
Author(s):  
Marian E. Melish ◽  
Sharon D. Uyeno ◽  
Donna S.Y. Ching ◽  
John Brunzell
Keyword(s):  
Lipoprotein Lipase ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Kawasaki Syndrome ◽  
Lipoprotein Lipase Activity

Effects of a High Caloric Diet with Heavy Exercise on Plasma Lipids and Lipoprotein Lipase Activity

1990 ◽  
Vol 18 (9-10) ◽  
pp. 897-901
Author(s):  
Masahiko NAMIKI ◽  
Masato NISHIWAKI ◽  
Mitsuo SUZUKAWA ◽  
Katsunori IKEWAKI ◽  
Humihiko HIRATA ◽  
...  
Keyword(s):  
Lipoprotein Lipase ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Lipoprotein Lipase Activity ◽  
Heavy Exercise ◽  
High Caloric Diet

scholarly journals Race, Visceral Adipose Tissue, Plasma Lipids, and Lipoprotein Lipase Activity in Men and Women

2000 ◽  
Vol 20 (8) ◽  
pp. 1932-1938 ◽  
Author(s):  
Jean-Pierre Després ◽  
Charles Couillard ◽  
Jacques Gagnon ◽  
Jean Bergeron ◽  
Arthur S. Leon ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Lipoprotein Lipase ◽  
Visceral Adipose Tissue ◽  
Lipase Activity ◽  
Plasma Lipids ◽  
Lipoprotein Lipase Activity ◽  
Men And Women ◽  
Visceral Adipose

scholarly journals Influence of cholesterol status on blood lipid and lipoprotein enzyme responses to aerobic exercise

2000 ◽  
Vol 89 (2) ◽  
pp. 472-480 ◽  
Author(s):  
Peter W. Grandjean ◽  
Stephen F. Crouse ◽  
J. James Rohack
Keyword(s):  
Lipoprotein Lipase ◽  
Lipase Activity ◽  
Cholesterol Ester ◽  
Plasma Lipids ◽  
Density Lipoprotein ◽  
Cholesterol Ester Transfer Protein ◽  
Lipoprotein Cholesterol ◽  
Lipoprotein Lipase Activity ◽  
Protein Activity ◽  
Transfer Protein

To compare postexercise changes in plasma lipids and lipoprotein enzymes in 13 hypercholesterolemic (HC) and 12 normocholesterolemic men [total cholesterol (TC) 252 ± 5 vs. 179 ± 5 mg/dl], fasting blood samples were obtained 24 h before, immediately, 24, and 48 h after a single bout of treadmill walking (70% peak O2consumption, 500 kcal expenditure). Significant findings ( P < 0.05 for all) for plasma volume-adjusted lipid and enzyme variables were that TC, low-density-lipoprotein cholesterol, and cholesterol ester transfer protein activity were higher in the HC group but did not influence the lipid responses to exercise. Across groups, TC was transiently reduced immediately after exercise but returned to baseline levels by 24 h postexercise. Decreases in triglyceride and increases in high-density-lipoprotein cholesterol (HDL-C) and HDL3-C were observed 24 h after exercise and lasted through 48 h. Lipoprotein lipase activity was elevated by 24 h and remained elevated 48 h after exercise. HDL2-C, cholesterol ester transfer protein activity, hepatic triglyceride lipase, and lecithin: cholesterol acyltransferase activities did not change after exercise. These data indicate that the exercise-induced changes in HDL-C and triglyceride are similar in HC and normocholesterolemic men and may be mediated, at least in part, by an increase in lipoprotein lipase activity.

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