Bioevaluation of Dietary Iron in Growing Rats. II. Relationship between the Iron Level in a Semolina Diet and the Response of Growing Rats

1968 ◽  
Vol 10 (4) ◽  
pp. 254-265
Author(s):  
A. Ahlström ◽  
P. Koivistoinen ◽  
Riitta Saloniemi ◽  
Paula Salo
Keyword(s):  
PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0120609 ◽  
Author(s):  
Murui Han ◽  
Jonghan Kim

2017 ◽  
Vol 57 (4) ◽  
pp. 778 ◽  
Author(s):  
K. Cui ◽  
Y. Tu ◽  
Y. C. Wang ◽  
N. F. Zhang ◽  
T. Ma ◽  
...  

The effects of restricting iron intake for the final 60 days of a 180-day growth trial on growth performance, nutrient digestibility, slaughter performance and meat quality of dairy bull calves used in veal production were evaluated in this study. Twenty-four newborn Holstein bull calves with an average weight of 41.0 ± 1.62 kg were randomly assigned to two groups of n = 12 calves/group. Calves in the Control group were fed a basal diet that included a milk replacer and pellet feed for 180 days. The iron level in the basal diet was 50 mg/kg. Calves in the Treatment group received the basal diet supplemented with 70 mg/kg iron for the first 120 days, then received the basal diet for the remaining 60 days. Five calves from each group were slaughtered at the end of the trial, and samples of the M. longissimus dorsi and rumen fluid were collected. No differences were found in dry matter intake, growth performance or digestibility and metabolism of nutrients between the two groups (P > 0.05). The dietary iron regimen did not affect the concentrations of blood urea nitrogen, total protein, albumin, or glucose (P > 0.05); however, the haemoglobin content increased with the supplementation of iron in the diet (P < 0.05). Compared with the Control group, increasing dietary iron increased the meat percentage (P < 0.05) rather than the meat nutritional composition or quality of veal.


1969 ◽  
Vol 11 (4) ◽  
pp. 251-258
Author(s):  
A. Ahlström ◽  
P. Koivistoinen ◽  
Riitta Tainio
Keyword(s):  

2010 ◽  
Vol 42 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Asuka Kamei ◽  
Yuki Watanabe ◽  
Tomoko Ishijima ◽  
Mariko Uehara ◽  
Soichi Arai ◽  
...  

Anemia can be induced by dietary iron deficiency, as well as by hemorrhagia. It may also be associated with changes in lipid metabolism. However, no global analysis detailing the consequences of iron deficiency in the liver has yet been conducted. Since the liver is a metabolically important organ and also a major iron-storing organ, we performed a comprehensive transcriptome analysis to determine the effects of iron deficiency on hepatic gene expression. Four-week-old rats were fed an iron-deficient diet, ∼3 ppm iron, ad libitum for 16 days. These rats were compared with similar rats pair-fed a control diet with a normal iron level, 48 ppm iron. The 16-day iron-deficient diet apparently induced anemia. On day 17, the rats were killed under anesthesia, and their livers were dissected for DNA microarray analysis. We identified 600 upregulated and 500 downregulated probe sets that characterized the iron-deficient diet group. In the upregulated probe sets, genes involved in cholesterol, amino acid, and glucose metabolism were significantly enriched, while genes related to lipid metabolism were significantly enriched in the downregulated probe sets. We also found that genes for caspases 3 and 12, which mediate endoplasmic reticulum (ER)-specific apoptosis, were upregulated in the iron-deficient group. Combined, these results suggest that iron deficiency exerts various influences, not only on nutrient metabolism but also on apoptosis, as a consequence of ER stress in the liver.


1967 ◽  
Vol 92 (1) ◽  
pp. 53-65 ◽  
Author(s):  
W. N. Pearson ◽  
Martha Reich ◽  
Helen Frank ◽  
Lourdes Salamat

1990 ◽  
Vol 38 (3) ◽  
pp. 601-604 ◽  
Author(s):  
Joseph Kanner ◽  
Ido Bartov ◽  
Menachem Ori Salan ◽  
Linda Doll

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