Ventricular Fibrillation in a Patient with ‘Silent’ Mitral Valve Prolapse

Cardiology ◽  
1988 ◽  
Vol 75 (2) ◽  
pp. 149-153 ◽  
Author(s):  
Boris Strasberg ◽  
Abraham Caspi ◽  
Jairo Kusniec ◽  
Ruben F. Lewin ◽  
Samuel Sclarovsky ◽  
...  
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Mitral Valve Prolapse

scholarly journals Sites of Successful Ventricular Fibrillation Ablation in Bileaflet Mitral Valve Prolapse Syndrome

2016 ◽  
Vol 9 (5) ◽  
Author(s):  
Faisal F. Syed ◽  
Michael J. Ackerman ◽  
Christopher J. McLeod ◽  
Suraj Kapa ◽  
Siva K. Mulpuru ◽  
...  
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Mitral Valve Prolapse

Abstract 20364: Successful Ablation of Ventricular Fibrillation in Malignant Bileaflet Mitral Valve Prolapse Syndrome

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Faisal F Syed ◽  
Peter Noseworthy ◽  
Christopher McLeod ◽  
Suraj Kapa ◽  
Siva Mulpuru ◽  
...  
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Papillary Muscle ◽  
Mitral Valve Prolapse ◽  
Left Ventricular ◽  
Beta Blockade ◽  
Successful Ablation ◽  
Procedural Success ◽  
Variable Coupling

Introduction: Although the vast majority of mitral valve prolapse (MVP) is benign, women with bileaflet MVP (biMVP), complex ventricular ectopy (VE), and abnormal T waves may comprise the recently described malignant biMVP syndrome. The mechanism of ventricular arrhythmia is unknown. To further characterize the arrhythmic substrate, we reviewed our center’s ablation experience in 6 biMVP patients with prior cardiac arrest and recurrent ICD shocks for drug refractory ventricular fibrillation (VF). Methods and Results: Six women with biMVP (median age 31.5 [range 24.2 - 58.7] years, EF 65 [45 - 67]%, all ≤moderate mitral regurgitation) experienced 6 (3 - 25) appropriate ICD shocks over 4.8 (2.8 - 10.7) years and underwent index ablation between 2/2007 - 10/2013. All had multiple VE morphologies (median 7 [3 - 24]) with variable coupling intervals but with a predominant VE trigger for the VF. A median 2 (1 - 4) VE foci were ablated. Sites of successful ablation of VF-triggering and other dominant VE were left ventricular papillary muscles [PM] (1 anterior, 1 posterior, 1 both), fascicles (1 anterior, 1 posterior), or both (1 both PM and posterior fascicle). Outflow tract VE was also present and targeted (1 left, 1 right)i. Two underwent repeat ablation (288 and 312 days) for recurrent complex VE without shocks, with different foci to the index ablation (1 posterior fascicle, 1 both fascicles). The VF-triggering VE in all patients was confirmed as originating from within the left fascicular system, which in 3/6 was at a papillary muscle. Acute procedural success was seen in all with no complications to date. A VF storm occurred within 24 hours of ablation in a single patient. At follow-up of a mean 662 (47 - 2099) days, 1 patient received a single shock (p=0.03 vs. preablation). Symptomatic VE was reduced in all; while 3/6 continue Class 1c antiarrhythmics and 5/6 have beta blockade. Conclusion: Malignant biMVP syndrome is characterized by fascicular and papillary muscle PVCs that trigger ventricular fibrillation, yet in all patients, the VE is multifocal. Ablation of at least one focus appears to improve symptoms and reduce shocks.

scholarly journals Ventricular fibrillation during general anaesthesia in a seven-year-old patient with mitral valve prolapse

1986 ◽  
Vol 33 (6) ◽  
pp. 795-798 ◽  
Author(s):  
Pierre A. Casthely ◽  
John Dluzneski ◽  
Marilyn A. Resurreccion ◽  
Nikitas Nikitas Kleopoulos ◽  
Vladimir Redko
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
General Anaesthesia ◽  
Mitral Valve Prolapse

scholarly journals Ventricular fibrillation and prolonged asystole in asymptomatic mitral annular disjunction

2021 ◽  
Author(s):  
Chiara Valeriano ◽  
Stefano Figliozzi ◽  
Lorenzo Monti
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Sinus Arrest ◽  
Prolonged Asystole

Abstract A previously asymptomatic 20-year-old woman with mitral valve prolapse presented with ventricular fibrillation. After subcutaneous cardiac defibrillator implantation, she experienced sinus arrest without ventricular escape.

Ventricular fibrillation due to severe mitral valve prolapse

2007 ◽  
Vol 116 (3) ◽  
pp. e101-e102 ◽  
Author(s):  
Christian Knackstedt ◽  
Karl Mischke ◽  
Thomas Schimpf ◽  
Philip Neef ◽  
Patrick Schauerte
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Mitral Valve Prolapse

scholarly journals Prevalence of mitral annulus disjunction and mitral valve prolapse in a multicenter cohort of idiopathic ventricular fibrillation patients

2021 ◽  
Vol 22 (Supplement_2) ◽  
Author(s):  
S Groeneveld ◽  
FP Kirkels ◽  
MJ Cramer ◽  
R Evertz ◽  
KH Haugaa ◽  
...  
Keyword(s):  
Ventricular Fibrillation ◽  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Mitral Annulus ◽  
Sudden Onset ◽  
Magnetic Resonance Images ◽  
Healthy Controls ◽  
Multicenter Cohort Study ◽  
Idiopathic Ventricular Fibrillation ◽  
Multicenter Cohort

Abstract Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Dutch Heart Foundation Background Idiopathic ventricular fibrillation (IVF) is diagnosed in patients with sudden onset of ventricular fibrillation of which the origin is not identified after extensive evaluations. Recent studies suggest an association between mitral annulus disjunction (MAD), mitral valve prolapse (MVP) and ventricular arrhythmias[1,2]. The prevalence of MAD and MVP in IVF patients in this regard, is not well established. Purpose To explore prevalence of MAD and MVP in IVF patients. Methods In this retrospective multicenter cohort study, Cardiac Magnetic Resonance images from IVF patients (i.e., negative for ischemia, cardiomyopathy and channelopathies) and matched control subjects were analyzed for MAD (≥2mm) and MVP (>2mm). Results In total, 71 IVF patients (mean age 39, 59% male) and 71 controls (mean age 41, 58% male) were included. MAD in the inferolateral wall was more prevalent in IVF patients versus healthy controls (6 [10%] vs. 1 [1%], p = 0.035). MVP was only seen in IVF patients and not in controls (4 [7%] vs. 0 [0%], p = 0.037). MVP was observed both in IVF patients with (n = 3) and without (n = 1) MAD. Patients with MAD did not show papillary muscle fibrosis. Four (67%) patients with MAD showed frequent ventricular ectopy from the basal myocardial region. Conclusion Inferolateral MAD and MVP were significantly more prevalent in IVF patients compared to healthy controls (figure). This is in line with previous studies suggesting a correlation between mitral valve disease and IVF. Our findings support further exploration of the pathophysiological mechanisms underlying a subset of IVF that associates with MAD and MVP.

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