Vasopressin Stimulates Urinary Kallikrein Excretion in the Isolated Erythrocyte-Perfused Rat Kidney

1988 ◽  
Vol 11 (1-2) ◽  
pp. 50-59
Author(s):  
Gregory W. Stephens ◽  
Wilfred Lieberthal ◽  
Narendra B. Oza ◽  
Robert Valeri ◽  
Norman G. Levinsky
Keyword(s):  
Rat Kidney ◽  
Urinary Kallikrein ◽  
Urinary Kallikrein Excretion ◽  
Perfused Rat Kidney

Inhibition of Urinary Kallikrein Excretion by Semi-Purified Renin in the Rat

1979 ◽  
Vol 57 (s5) ◽  
pp. 243s-245s ◽  
Author(s):  
H. R. Croxatto ◽  
G. Silva ◽  
M. Boric
Keyword(s):  
Urinary Excretion ◽  
Considerable Increase ◽  
Rat Kidney ◽  
Renin Activity ◽  
Purification Procedure ◽  
Urinary Kallikrein ◽  
Sodium Potassium ◽  
Water Excretion ◽  
Urinary Kallikrein Excretion ◽  
Natriuretic Effect

1. Rat kidney extracts obtained at successive stages of a purification procedure, which allows the separation of renin and kallikrein, were used in order to investigate their effect upon urinary excretion of kallikrein, sodium, potassium and water in hyperhydrated rats. 2. Only the purified fraction containing renin reduced kallikrein excretion. The decrease of kallikrein coincided with a considerable increase in sodium, potassium and water excretion. 3. The natriuretic effect of renin extract did not depend on the presence of kallikrein. The injection of a mixture of renin and kallikrein attenuated the effect of renin alone, indicating that both enzymes exert antagonistic actions on the excretion of electrolytes and water by the kidneys. 4. A purified fraction of kidney extract containing no kallikrein and only traces of renin activity, had a stimulatory effect on kallikrein, water and elctrolyte excretion.

Validation of a toxicity testing model by evaluating oxygen supply and energy state in the isolated perfused rat kidney

1991 ◽  
Vol 25 (3) ◽  
pp. 195-204 ◽  
Author(s):  
Takano Takehito ◽  
Nakata Kazuyo ◽  
Kawakami Tsuyoshi ◽  
Miyazaki Yoshifumi ◽  
Murakami Masataka ◽  
...  
Keyword(s):  
Oxygen Supply ◽  
Energy State ◽  
Rat Kidney ◽  
Toxicity Testing ◽  
Testing Model ◽  
Isolated Perfused Rat Kidney ◽  
Perfused Rat Kidney

Aldosterone Effects on Renal Function in the Isolated Perfused Rat Kidney

1979 ◽  
Vol 2 (1) ◽  
pp. 1-11
Author(s):  
Richard Solomon ◽  
Patricio Silva ◽  
Franklin H. Epstein
Keyword(s):  
Renal Function ◽  
Rat Kidney ◽  
Isolated Perfused Rat Kidney ◽  
Perfused Rat Kidney

Thromboxane and Prostacyclin Production by Irradiated and Perfused Rat Kidney

1987 ◽  
pp. 219-224 ◽  
Author(s):  
Z. Weshler ◽  
A. Raz ◽  
E. Rosenmann ◽  
S. Biran ◽  
Z. Fuks ◽  
...  
Keyword(s):  
Rat Kidney ◽  
Perfused Rat Kidney ◽  
Prostacyclin Production
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