L-2-Oxothiazolidine-4-Carboxylate and N-Acetylcysteine as Precursors of Intracellular Glutathione in Human Peritoneal Mesothelial Cells

1996 ◽  
Vol 14 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Andrzej Breborowicz ◽  
Athina Patrikarea ◽  
Leo Martis ◽  
D.G. Oreopoulos
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Intracellular Glutathione ◽  
Human Peritoneal Mesothelial Cells

Intracellular Glutathione in Human Peritoneal Mesothelial Cells Exposed in vitro to Dialysis Fluid

1996 ◽  
Vol 19 (5) ◽  
pp. 268-275 ◽  
Author(s):  
A. Breborowicz ◽  
H. Rodela ◽  
L. Martis ◽  
D.G. Oreopoulos
Keyword(s):  
Mesothelial Cells ◽  
Dialysis Fluid ◽  
Time Intervals ◽  
Peritoneal Mesothelial Cells ◽  
Dialysis Solution ◽  
Intracellular Glutathione ◽  
Human Peritoneal Mesothelial Cells ◽  
Dialysis Fluids

Effect of peritoneal dialysis fluids on glutathione (GSH/GSSG) level in human peritoneal mesothelial cells was tested in in vitro experiments. To mimic in vivo conditions, cells were initially exposed to dialysis fluids (Dianeal 1.36%, Dianeal 2.27%, Dianeal 3.86%) that subsequently were diluted with dialysate effluent at time intervals. GSH/GSSG concentration in cells initially decreased but returned to normal values thereafter. This decrease in the intracellular concentration of glutathione was less when pH of the tested dialysis fluid was adjusted to 7.3. In further experiments with mesothelial cells exposed to Earle's salts solution supplemented with glucose and/or lactate, we have shown that in the presence of low pH, lactate is the main factor causing depletion of intracellular glutathione. When added to the dialysis solution at a concentration of 0.1 mM, L-2-oxothiazolidine-4-carboxylate, a precursor of glutathione, not only prevents the initial decrease in glutathione concentration but also augments the final intracellular level of this thiol.

scholarly journals Effect of nonreducing saccharides to human peritoneal mesothelial cells(HPMC)

2005 ◽  
Vol 17 (Supplement) ◽  
pp. 83-83
Author(s):  
Yusuke Nakano ◽  
Keiichi Miyamoto ◽  
Takashi Horiuchi ◽  
Hirokatsu Miwa ◽  
Hitoshi Mitsudumi
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Human Peritoneal Mesothelial Cells

scholarly journals Expression of glucose transporters in human peritoneal mesothelial cells

1998 ◽  
Vol 53 (5) ◽  
pp. 1278-1287 ◽  
Author(s):  
Bernd Schröppel ◽  
Michael Fischereder ◽  
Patrick Wiese ◽  
Stephan Segerer ◽  
Stephan Huber ◽  
...  
Keyword(s):  
Glucose Transporters ◽  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Human Peritoneal Mesothelial Cells

scholarly journals Hyperosmolality suppresses but TGF β 1 increases MMP9 in human peritoneal mesothelial cells

1997 ◽  
Vol 51 (1) ◽  
pp. 337-347 ◽  
Author(s):  
Jean-Philippe Rougier ◽  
Philippe Moullier ◽  
Rémi Piedagnel ◽  
Pierre M. Ronco ◽  
with the technical assistance of Sophie Guia
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Human Peritoneal Mesothelial Cells

Glucose but not N-Acetylglucosamine Accelerates in vitro Senescence of Human Peritoneal Mesothelial Cells

2011 ◽  
Vol 34 (6) ◽  
pp. 489-494 ◽  
Author(s):  
Marta Ciszewicz ◽  
George Wu ◽  
Paul Tam ◽  
Alicja Połubinska ◽  
Andrzej Bręborowicz
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Human Peritoneal Mesothelial Cells

scholarly journals miRNA-199a/214 Cluster Enhances Fibrosis of Human Peritoneal Mesothelial Cells Regulated by SRF

2015 ◽  
Vol 17 (2) ◽  
pp. S119
Author(s):  
Lijie He ◽  
Shiren Sun ◽  
Hanmin Wang ◽  
Jinping Hu ◽  
Tiantian Shi
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Human Peritoneal Mesothelial Cells

Buffer-dependent regulation of aquaporin-1 expression and function in human peritoneal mesothelial cells

2012 ◽  
Vol 27 (7) ◽  
pp. 1165-1177 ◽  
Author(s):  
Yihui Zhai ◽  
Jacek Bloch ◽  
Meike Hömme ◽  
Julia Schaefer ◽  
Thilo Hackert ◽  
...  
Keyword(s):  
Mesothelial Cells ◽  
Peritoneal Mesothelial Cells ◽  
Aquaporin 1 ◽  
Human Peritoneal Mesothelial Cells ◽  
And Function
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