Apex-Carotis Diagram as Related to Systolic and Diastolic Time Intervals in Myocardial Infarction

Cardiology ◽  
1978 ◽  
Vol 63 (3) ◽  
pp. 129-138
Author(s):  
Nikolai S. Kolev
Keyword(s):  
Myocardial Infarction ◽  
Time Intervals ◽  
Diastolic Time

Time-related changes in the diagnostic utility of total lactate dehydrogenase, lactate dehydrogenase isoenzyme-1, and two lactate dehydrogenase isoenzyme-1 ratios in serum after myocardial infarction

1990 ◽  
Vol 36 (7) ◽  
pp. 1317-1322 ◽  
Author(s):  
L V Galbraith ◽  
F Y Leung ◽  
G Jablonsky ◽  
A R Henderson
Keyword(s):  
Myocardial Infarction ◽  
Lactate Dehydrogenase ◽  
Likelihood Ratio ◽  
Roc Curve ◽  
Operating Characteristic ◽  
Negative Likelihood Ratio ◽  
Diagnostic Utility ◽  
Time Intervals ◽  
Dehydrogenase Isoenzyme ◽  
Cardiac Care Unit

Abstract Using receiver-operating characteristic (ROC) curve and likelihood ratio analysis, we examined the diagnostic utility of total lactate dehydrogenase (LD; EC 1.1.1.27) activity (I). LD isoenzyme-1 activity (II), and the LD-1 percentage of total LD activity (III), LD-1 LD-2 (IV), and LD-1/LD-4 (V) in 347 persons admitted to the Cardiac Care Unit (of whom 173 were subsequently proven to have had myocardial infarction). Blood was sampled from these subjects at about 6-h intervals for up to 96 h from the onset of chest pain. Defining an "effective" test as one having an area under the ROC curve of greater than or equal to 0.9, we determined the ranked utility (greatest to least) of these tests as V = IV greater than III greater than II greater than I. Tests III, IV, and V had by this criterion, diagnostic effectiveness equivalent to measurements of creatine kinase-2 in serum but in samples obtained at later time intervals. The decision thresholds for both high (constant) test sensitivity and specificity varied with time, to differing extents, over the entire 96-h period, a finding with important diagnostic implications. We document positive and negative likelihood ratio values for each of these tests throughout the entire period of study.

Systolic and diastolic time intervals in pulsus alternans

1974 ◽  
Vol 87 (1) ◽  
pp. 5-10 ◽  
Author(s):  
David H. Spodick ◽  
Abdul H. Khan ◽  
Veronica M. Quarry
Keyword(s):  
Time Intervals ◽  
Pulsus Alternans ◽  
Diastolic Time

Diastolic Time Intervals and Systolic Time Intervals in Hypertensive Patients

1984 ◽  
Vol 14 (1) ◽  
pp. 103
Author(s):  
Han Su Kim ◽  
Jong Eun Park ◽  
Hak Yang Kim ◽  
Kwon Sam Kim ◽  
Myung Shick Kim ◽  
...  
Keyword(s):  
Systolic Time Intervals ◽  
Time Intervals ◽  
Hypertensive Patients ◽  
Systolic Time ◽  
Diastolic Time

scholarly journals Evaluation of Cardiovascular Experiment Animal

2021 ◽  
Vol 9 (12) ◽  
pp. 2305-2310
Author(s):  
Kirtane Ramesh Kirtane
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery ◽  
Time Course ◽  
Muscle Fibers ◽  
Early Mortality ◽  
Ground Substance ◽  
Coronary Artery Ligation ◽  
Time Intervals ◽  
In Vivo Models ◽  
Immunohistochemical Studies

Abstract: In vivo models of myocardial infarction induced by coronary artery ligation in rats usually suffer from high early mortality and a low rate of induction. This study investigated the time course initiation of chronic myocardial infarction in albino rats and the possibility of reducing early mortality rate due to myocardial infarction by modification of the surgical technique. CAL was carried out by passing the suture through the pericardial layer around the midway of the left anterior descending coronary artery including a small area of the myocardium to avoid mechanical damage to the heart geometry. In addition, the role of endothelin-1 in rat heart with congestive heart failure was critically assessed. Time course initiation experiments were designed by sacrificing the animals at different time intervals and by carrying out physiological, biochemical, histopathological, electron microscopical and immunohistochemical studies. Specific markers of myocardial injury, viz. cardiac troponin-T, high sensitivity C-reactive protein, lactate dehydrogenase and fibrinogen were measured at different time points. Serum marker enzymes and activities of lysosomal hydrolases were found to be elevated on the eighth day post-ligation. Histopathological studies demonstrated focal areas showing fibrovascular tissue containing fibroblasts, collagenous ground substance and numerous small capillaries replacing cardiac muscle fibers. Transmission electron micrographs exhibited mitochondrial changes of well-developed irreversible cardiac injury, viz. swelling, disorganization of cristae, appearance of mitochondrial amorphous matrix densities, and significant distortion of muscle fibers and distinct disruption of the intercalated discs. Immune blotting studies confirmed the presence of alpha 2-macroglobulin which supported the inflammatory response. The severity of the CMI was inferred by the measurement of the level of ET-1 in plasma and left ventricle which was significantly higher in the CMI rats than in the sham-operated rats. Immunohistochemical studies at different time intervals showed that there was a significant immunoexpression of ET-1 on the eighth day post-ligation. This study conclusively showed that ligation of left anterior descending artery minimised mortality and ET-1 was expressed during CMI.

scholarly journals Impact of unstable angina on operative mortality with coronary revascularization at varying time intervals after myocardial infarction

1991 ◽  
Vol 102 (6) ◽  
pp. 867-873 ◽  
Author(s):  
Jack J. Curtis ◽  
Joseph T. Walls ◽  
Nazih H. Salam ◽  
Theresa M. Boley ◽  
Weerachai Nawarawong ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Unstable Angina ◽  
Operative Mortality ◽  
Coronary Revascularization ◽  
Time Intervals

Systolic time intervals after phenylephrine administration for early stratification of patients after acute myocardial infarction

1994 ◽  
Vol 73 (1) ◽  
pp. 6-10 ◽  
Author(s):  
Michael Kyriakidis ◽  
Athanassios Antonopoulos ◽  
Fotis Georgiakodis ◽  
Panaghiotis Petropoulakis ◽  
Evangelos Georgiou ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Systolic Time Intervals ◽  
Time Intervals ◽  
Systolic Time
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